Pneumonia News and Research

Latest Pneumonia News and Research

Electronic doctors’ notes could help hospitals plan for surges in COVID-19 cases

A new study, published today in Nature Digital Medicine, found that 'natural language processing' (NLP) of information routinely recorded by doctors - as part of patients' electronic health records - reveal vital trends that could help clinical teams forecast and plan for surges in patients.

24 Feb 2021

Basigin does not facilitate SARS-CoV-2 entry, say researchers

Researchers investigated the significance of a transmembrane glycoprotein basigin, or CD147, as a host cell co-receptor required for the entry of SARS-CoV-2. The findings reveal that recombinant human basigin does not interact with full-length spike protein or spike RBD of SARS-CoV-2.

24 Feb 2021

Corticosteroid receptor inhibitor shows anti-SARS-CoV-2 activity in vivo

A team of researchers examined PT150, which is an allosteric modulator of androgen and glucocorticoid receptors, to assess whether it had any antiviral activity or immunomodulatory activity to decrease the hyperinflammatory response of SARS-CoV-2 infection.

24 Feb 2021

Hyperactive immune system contributes to COVID-19 severity, lung damage

Researchers have pinpointed a helper T cell population in the lungs of patients with severe COVID-19 that may be central to the development of hyperinflammation, lung injury, and subsequent acute respiratory distress syndrome (ARDS) during disease.

24 Feb 2021

COVID-19 may alter host proteins to cause autoimmunity

To better understand the transient and chronic autoimmune symptoms caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, researchers from Memorial Sloan Kettering Cancer Center, Guizhou Medical University, and biotech company Curandis embarked on an endeavor to establish a comprehensive autoantigenome for COVID19.

23 Feb 2021

‘Resuscitating’ old antibiotics to combat the growing threat of superbugs

Holding off the rise of superbugs could be achieved by 'resuscitating' old antibiotics, with The University of Queensland researchers leading an international project to help combat the growing threat.

23 Feb 2021

Glycan switch may explain why SARS-CoV-2 causes such variable symptoms

Researchers in Portugal have provided evidence that might explain why infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes mild or even asymptomatic illness in some individuals, but severe coronavirus disease 2019 (COVID-19) in others.

23 Feb 2021

Influenza A virus defective interfering particles against SARS-CoV-2

In the search for a broadly acting pan-specific antiviral, an interdisciplinary team from Germany tested the previously proposed (for antiviral treatment against Influenza A infections) - Influenza A virus (IAV) defective interfering particles (DIPs). The research is published online on the bioRxiv preprint server.

23 Feb 2021

Failed antiviral response in nasal mucosa may predict severe COVID-19

Researchers in the United States have conducted a study suggesting that the host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within nasal mucosa is a key determinant of clinical trajectory in coronavirus disease 2019 (COVID-19).

22 Feb 2021

Human monoclonal antibodies can act as a substitute for traditional antibiotics

In the course of a new and groundbreaking study, led by Dr, Natalia Freund and the doctoral candidate Avia Waston at the Sackler Medical Faculty, the research group succeeded in isolating monoclonal antibodies, which hindered the growth of tuberculosis germs in laboratory mice. The

22 Feb 2021

Long-term exposure to air pollution can increase cardiovascular and respiratory risks

Exposure to what is considered low levels of air pollution over a long period of time can increase the risk of heart attack, stroke, atrial fibrillation, and pneumonia among people ages 65 and older, according to new research published today in the American Heart Association's flagship journal Circulation.

22 Feb 2021

Chicken-derived antibody shows potent neutralizing capacity against SARS-CoV-2 in vitro

Researchers report on a Chicken-derived antibody against SARS-CoV-2, offering preliminary data on a potential therapeutic for COVID-19 warranting further research.

19 Feb 2021

COVID-19 and lung cancer have a common pathway, say researchers

A new preprint on the bioRxiv* server describes the common features COVID-19 shares with lung cancer.

19 Feb 2021

China's SARS and SARS-CoV-2 outbreak management in comparative perspective

A new study compares the current SARS-CoV-2 outbreak with the earlier SARS-CoV epidemic to understand the best way to respond to it sensitively and flexibly. This involves early detection, using multiple screening tests, followed by management of the clinical features as required, in order to prevent disease-related injury.

17 Feb 2021

A pangolin coronavirus spike glycoprotein sheds light on SARS-CoV-2’s evolution

As the exact zoonotic origin of SARS-CoV-2 remains unresolved, scientists at the Francis Crick Institute in London, UK, explored the structure and binding properties of a Pangolin coronavirus spike glycoprotein to see if it could shed light on the evolution of SARS-CoV-2.

16 Feb 2021

Researchers develop protocols for rapid serological surveys of SARS-CoV-2 infection

A new study by researchers from Emory and Yale Universities in the USA discusses a design for quickly launching serological surveys to assess the prevalence of this infection in a given population.

15 Feb 2021

Researchers study host and viral transcriptomes in tandem to shed light on SARS-CoV-2 infection

In a new study, researchers discuss the use of simultaneous sequencing of both human and viral genes to better understand SARS-CoV-2's infection pathway.

15 Feb 2021

FDA approves drug to reduce frequency of chemotherapy-induced bone marrow suppression

Today, the U.S. Food and Drug Administration approved Cosela (trilaciclib) as the first therapy in its class to reduce the frequency of chemotherapy-induced bone marrow suppression in adults receiving certain types of chemotherapy for extensive-stage (when the cancer has spread beyond the lungs) small cell lung cancer.

13 Feb 2021

Statins shown to reduce COVID-19 severity and lower mortality

Much attention has been focused on ways to reduce the deadly exaggeration of normal inflammatory reactions to this pathogen. A new research paper posted to the medRxiv* preprint server describes the alleviation of hyper-inflammatory phenomena following the administration of statins, drugs more widely known for their use in reducing blood cholesterol levels, to patients with COVID-19.

11 Feb 2021

SARS-CoV-2 evolves antibody resistance in immunocompromised patient

Researchers in the United States who tracked the evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an immunocompromised patient found that convalescent plasma therapy was associated with the emergence of viral variants that were less susceptible to neutralizing antibodies.

11 Feb 2021