Sepsis News and Research

Latest Sepsis News and Research

New study alters guidelines for management of sepsis

A new study that measured the reliability of administering antibiotics before obtaining blood cultures could end the debate among physicians regarding sepsis management.

18 Sep 2019

New strain of Streptococcus A rampant in England and Wales

According to a new study on cases of scarlet fever and other Streptococcus A infections in England and Wales, the recent rise in cases is due to a newly identified strain. This accounted for the great increase in the number of cases of scarlet fever that occurred in 2014. The last such outbreak was way back in the 1960s.

11 Sep 2019

New model for vaginal microbiome transplantation

Bacterial vaginosis is a condition affecting thousands of women worldwide, and is associated not only with vaginal symptoms but with pregnancy-related complications including preterm labor and stillbirth. Now researchers have come up with an effective way to replace the unhealthy vaginal microflora with a ready-to-use microbiome – called a vaginal microbiome transplantation (VMT).

11 Sep 2019

Identifying signs and symptoms of sepsis can reduce the number of fatal cases

Despite killing hundreds of thousands of Americans every year, sepsis is a condition few people know about.

11 Sep 2019

Scientists discover new strain of group A streptococcus bacteria in England and Wales

A team of scientists led by Imperial College London have discovered a new strain of group A streptococcus bacteria.

11 Sep 2019

EEG slowing may be a valuable biomarker for delirium severity

An EEG (electroencephalogram) can provide a valuable biomarker for detecting delirium, a serious mental disturbance that is often underrecognized, as well as predicting poor clinical outcomes, researchers from Massachusetts General Hospital have found.

11 Sep 2019

ICU bloodstream infections have reduced by 80%, research shows

Bloodstream infections acquired in UK Intensive Care Units reduced by 80% between 2007 and 2012, according to research funded by the NIHR Guy's and St Thomas' Biomedical Research Centre.

10 Sep 2019

Study: One-third of children admitted in ICUs for sepsis show PTSD symptoms

Doctors have found that children who have been in Intensive Care Units (ICUs) for sepsis have a significantly increased risk of Post-Traumatic Stress Disorder (PTSD), with around 1/3 showing PTSD symptoms.

8 Sep 2019

Sepsis care quality improvement program saves lives and reduces healthcare costs

A sepsis care quality improvement program saves lives, shortens hospital stays and reduces healthcare costs, according to a study by researchers at Loyola Medicine and Loyola University Chicago.

5 Sep 2019

Resuscitation from hemorrhagic shock via transfusion of anaerobically stored RBCs improves outcomes

Transfusion of red blood cells (RBCs) stored anaerobically – in the absence of oxygen – is a promising technique to improve resuscitation from hemorrhagic shock, according to animal studies reported in SHOCK: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Official Journal of the Shock Society.

4 Sep 2019

$15 million grant funds new effort to develop universal vaccine for strep throat infections

CARB-X, an international non-profit partnership of private, academic and government institutions, has awarded SutroVax, Inc., a Northern California-based biopharmaceutical company, with an award of up to $15 million to develop a universal vaccine for Group A Streptococcus, the bacteria that causes pharyngitis or strep throat.

4 Sep 2019

Novel approach could help prevent sepsis in burn patients

Immediately following severe burns, bacteria reach the wound from different sources, including the patient's skin, gastrointestinal tract, respiratory tracts and health care-related human contact.

4 Sep 2019

Bacterial endotoxin testing now offered by Perfectus Biomed

Endotoxins are toxins present within a bacterial cell wall that are released when a cell disintegrates. They are lipopolysaccharides (LPS) and are found within the outer membrane of the cell wall of Gram-negative bacteria. Endotoxins often consist of lipid A, a core oligosaccharide and the O-specific polysaccharide.

From Perfectus Biomed 3 Sep 2019

Pneumonia uses hydrogen peroxide to weaken the immune system

Pneumonia is a lung infection, filling up the alveoli with pus and fluid. At present, it’s the leading cause of death among children. The lung infection accounts for 15 percent of all deaths in children below five years old, killing more than 800,000 children in 2017 alone.

3 Sep 2019

Rapid antimicrobial susceptibility test could deliver results from lab to GPs in under two hours

The threat of antibiotic-resistant strains of infection is an escalating global health concern and improved targeting of antibiotics is crucial in reducing the spread of resistance.

30 Aug 2019

Researchers target cancer's protective barrier

Cancer cells are notorious for their camouflage work, which enables them to escape immune targeting. Now scientists are learning how to strip away the disguise and allow the immune system to do its work, by targeting cells called myeloid-derived suppressor cells (MDSCs) that shield the tumor. This would also enhance the effectiveness of newer cancer immunotherapies like Chimeric-Antigen Receptor T cell (CAR-T).

26 Aug 2019

Researchers discover new way to stop inflammation in the lungs due to sepsis, injury

University of Calgary researchers at the Cumming School of Medicine (CSM) led by Drs. Donna Senger, PhD, Paul Kubes, PhD, and Stephen Robbins, PhD have discovered a new way to stop harmful inflammation in the lungs due to sepsis and injury.

25 Aug 2019

Investigating organ crosstalk leads to a better understanding of sepsis

Sepsis, a complex systemic response to infection leading to organ failure, is generally studied at the level of individual organs; this research has hinted at altered metabolic changes.

20 Aug 2019

Sepsis digital alert system could save lives says NHS

According to the NHS, many lives across the country could be saved with the new and improved digital alert system for possible cases of sepsis at hospitals.

19 Aug 2019

Removal of a critical enzyme may help cases of sepsis finds research

Scientists at the University of California San Diego School of Medicine have shown that removal of an enzyme called the PH domain Leucine-rich repeat Protein Phosphatase 1 (PHLPP1) could help laboratory mice with sepsis in a model they had created for their experiment. The study titled, “PHLPP1 counter-regulates STAT1-mediated inflammatory signalling,” was published this week in the journal eLife.

15 Aug 2019