Sepsis News and Research

Latest Sepsis News and Research

Sepsis care quality improvement program saves lives and reduces healthcare costs

A sepsis care quality improvement program saves lives, shortens hospital stays and reduces healthcare costs, according to a study by researchers at Loyola Medicine and Loyola University Chicago.

5 Sep 2019

Resuscitation from hemorrhagic shock via transfusion of anaerobically stored RBCs improves outcomes

Transfusion of red blood cells (RBCs) stored anaerobically – in the absence of oxygen – is a promising technique to improve resuscitation from hemorrhagic shock, according to animal studies reported in SHOCK: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Official Journal of the Shock Society.

4 Sep 2019

$15 million grant funds new effort to develop universal vaccine for strep throat infections

CARB-X, an international non-profit partnership of private, academic and government institutions, has awarded SutroVax, Inc., a Northern California-based biopharmaceutical company, with an award of up to $15 million to develop a universal vaccine for Group A Streptococcus, the bacteria that causes pharyngitis or strep throat.

4 Sep 2019

Novel approach could help prevent sepsis in burn patients

Immediately following severe burns, bacteria reach the wound from different sources, including the patient's skin, gastrointestinal tract, respiratory tracts and health care-related human contact.

4 Sep 2019

Bacterial endotoxin testing now offered by Perfectus Biomed

Endotoxins are toxins present within a bacterial cell wall that are released when a cell disintegrates. They are lipopolysaccharides (LPS) and are found within the outer membrane of the cell wall of Gram-negative bacteria. Endotoxins often consist of lipid A, a core oligosaccharide and the O-specific polysaccharide.

From Perfectus Biomed 3 Sep 2019

Pneumonia uses hydrogen peroxide to weaken the immune system

Pneumonia is a lung infection, filling up the alveoli with pus and fluid. At present, it’s the leading cause of death among children. The lung infection accounts for 15 percent of all deaths in children below five years old, killing more than 800,000 children in 2017 alone.

3 Sep 2019

Rapid antimicrobial susceptibility test could deliver results from lab to GPs in under two hours

The threat of antibiotic-resistant strains of infection is an escalating global health concern and improved targeting of antibiotics is crucial in reducing the spread of resistance.

30 Aug 2019

Researchers target cancer's protective barrier

Cancer cells are notorious for their camouflage work, which enables them to escape immune targeting. Now scientists are learning how to strip away the disguise and allow the immune system to do its work, by targeting cells called myeloid-derived suppressor cells (MDSCs) that shield the tumor. This would also enhance the effectiveness of newer cancer immunotherapies like Chimeric-Antigen Receptor T cell (CAR-T).

26 Aug 2019

Researchers discover new way to stop inflammation in the lungs due to sepsis, injury

University of Calgary researchers at the Cumming School of Medicine (CSM) led by Drs. Donna Senger, PhD, Paul Kubes, PhD, and Stephen Robbins, PhD have discovered a new way to stop harmful inflammation in the lungs due to sepsis and injury.

25 Aug 2019

Investigating organ crosstalk leads to a better understanding of sepsis

Sepsis, a complex systemic response to infection leading to organ failure, is generally studied at the level of individual organs; this research has hinted at altered metabolic changes.

20 Aug 2019

Sepsis digital alert system could save lives says NHS

According to the NHS, many lives across the country could be saved with the new and improved digital alert system for possible cases of sepsis at hospitals.

19 Aug 2019

Removal of a critical enzyme may help cases of sepsis finds research

Scientists at the University of California San Diego School of Medicine have shown that removal of an enzyme called the PH domain Leucine-rich repeat Protein Phosphatase 1 (PHLPP1) could help laboratory mice with sepsis in a model they had created for their experiment. The study titled, “PHLPP1 counter-regulates STAT1-mediated inflammatory signalling,” was published this week in the journal eLife.

15 Aug 2019

Removing single enzyme improves outcomes in mouse model of sepsis

Sepsis occurs when the body goes overboard in its attempt to fight off an infection. Immune cells rush in, overreact and wreak havoc on tissues and organs, often resulting in organ failure and death.

14 Aug 2019

Newborn mouse model yields clues to cause of devastating gut disease in anemic preemies

Physicians have long suspected that red blood cell transfusions given to premature infants with anemia may put them in danger of developing necrotizing enterocolitis, or NEC, a potentially lethal inflammatory disease of the intestines.

From Johns Hopkins Medicine 13 Aug 2019

Researchers emphasize need for better test to diagnose urinary tract infections

Doctors urgently need a fast and accurate test for diagnosing urinary tract infections to reduce overprescribing of antibiotics, according to health researchers.

13 Aug 2019

Antibody may help the immune system fight sepsis-related fungal infections

An antibody that blocks the "programmed cell death" pathway may help the immune system fight off sepsis-related fungal infections, according to animal studies reported in SHOCK: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Official Journal of the Shock Society.

12 Aug 2019