Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Association between SARS-CoV-2 infections and areal level deprivation and ethnicity in England

A new study from the UK shows that the presence of inequality favors a heavier impact and that this showed dynamic changes as policies changed and newer virus variants emerged.

11 Nov 2021

COVID-19 trends identified from multiple linked EHR

In this study, the sociodemographic factors, occurrence of health conditions, the effect of the first and second waves in England, and vaccination effects, were considered separately.

11 Nov 2021

Corrected method for more accurate estimation of SARS-CoV-2 reproduction number

Scientists have recently proposed and applied a correction to EpiEstim, a statistical method to estimate the time-dependent transmission of infectious disease during an epidemic.

11 Nov 2021

Phage-like particle system provides a platform for quick and easy vaccine generation

In this study, researchers report on the development of a monovalent lambda PLP-based vaccine against SARS-CoV-2 or MERS-Cov through decoration with the spike RBD proteins from either virus.

11 Nov 2021

Effectiveness of sotrovimab demonstrated in patients with mild to moderate COVID-19

In an attempt to study the safety and effectiveness of sotrovimab in more vulnerable patients suffering from mild to moderate symptoms of COVID-19, a multinational team of researchers conducted the COVID-19 Monoclonal antibody Efficacy Trial-Intent to Care Early (COMET-ICE) trial.

11 Nov 2021

Surveillance approaches to monitor the presence of SARS-CoV-2 in a fully vaccinated population

Researchers at the University of Calgary Health Technology Assessment Unit investigated scientific evidence on various surveillance and testing methods to monitor the presence of the virus in a vaccinated population.

10 Nov 2021

Evidence that mild and even asymptomatic SARS-CoV-2 infection can lead to sustained immune activation

A paper published in the open-access journal Viruses, reports on a study investigating long-term changes to soluble inflammatory factors and cellular immune phenotype and function in 22 survivors of mild SARS-CoV-2 infection. The observations were then compared to 11 individuals who had recovered from other mild respiratory infections.

10 Nov 2021

First detection of SARS-CoV-2 remdesivir resistance in an immunocompromised patient

A research group from the US (led by experts from Yale University School of Medicine) recently presented a case of an immunocompromised female patient with acquired deficiency of B lymphocytes who subsequently developed a protracted course of the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

10 Nov 2021

Emergence of SARS-CoV-2 immune escape variants in an immunocompromised patient

A German case study recently published in the journal Nature Communications has characterized a long-term severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection dynamics in an immunosuppressed kidney transplant recipient and provided evidence for the evolution of SARS-CoV-2 into potentially harmful immune escape mutants during persistent infections.

10 Nov 2021

Risk of severe COVID-19 is rare among fully vaccinated individuals in England

A team of UK-based scientists has recently estimated the prevalence of vaccine breakthrough infections and severe disease in a large number of individuals fully vaccinated against coronavirus disease 2019 (COVID-19) in England.

10 Nov 2021

Coronaviruses synthesize RNA in membrane-bound compartments

A team of researchers show that IBV viral RNA synthesis occurs within the membrane-bound compartment

10 Nov 2021

The immune response elicited by an inactivated SAR-CoV-2 vaccine

A team of researchers assessed antibody responses to the inactivated SARS-CoV-2 vaccine among vaccine recipients in Shenzhen, China.

10 Nov 2021

The SARS-CoV-2 Beta variant evades Fc effector function by ancestral strain, study says

A new study finds improved Fc cross-reactivity against certain SARS-CoV-2 variant of concern.

10 Nov 2021

Stenoparib effectively inhibits SARS-CoV-2 variants in vitro

A new study assesses the antiviral activity of stenoparib against four SARS-CoV-2 strains.

10 Nov 2021

The autoantibody profile in COVID-19 patients with MIS-C

A new study assessed the presence of autoantibodies against autoantigens associated with known autoimmune diseases in patients with COVID-19.

10 Nov 2021

Current understanding of the link between COVID-19 and cardiovascular disease

A review published in Chemo-Biological Interactions has focused on the prevalence of COVID-19 in CVD patients associated with ACE2 mechanisms.

10 Nov 2021

Chronological changes in SARS-CoV-2 immune responses after BNT162b2 vaccine

A new study focused on the chronological changes in humoral and cell-mediated immune responses, during and after the BNT162b2 vaccine administration, among hospital workers of a national medical institution in Japan.

10 Nov 2021

Cell-based viral replication system for screening of SARS-CoV-2 drugs

The current study reports a SARS-CoV-2 replicon system within stable cell lines that can be cultured with ease in a standard biosafety level 2 laboratory.

10 Nov 2021

How effective are mask-wearing and social distancing in UK universities?

A new paper describes the effects of various non-pharmaceutical interventions in dealing with the spread of this virus among students, faculty, and staff on university campuses following the reopening of these institutions.

10 Nov 2021