Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Study reveals variable sites in novel coronavirus SARS-CoV-2

Understanding the varying aggressiveness of SARS-CoV-2 may provide valuable data to trace its spread across populations. In the study, published on the preprint server BioRxiv, the researchers traced amino acid variants that possess high frequency in Europe, particularly in Italy, one of the hardest-hit countries.

4 May 2020

Scientists develop CRISPR-based test for SARS-CoV-2

Now, a team of scientists at the University of California Santa Barbara has developed a low-cost, rapid, and high-tech test that can detect SARS-CoV-2 effectively. They have developed a CRISPR-based test that is sensitive and effective as traditional tests.

4 May 2020

SARS-CoV-2 receptor ‘mimic' could prevent COVID-19

Researchers from Italy have developed an exciting new peptide drug that could potentially prevent the coronavirus from infecting people’s cells. The paper, published on the preprint server bioRxiv* in April 2020, describes a small molecule that can bind to and block the attachment site on the virus spike protein, preventing its entry into the host cell.

4 May 2020

Impact of COVID-19 on pregnancy and breastfed infants

Pregnant women are among those at high risk of developing COVID-19, as confirmed in Wuhan early in the pandemic. A new study from Portugal published on the preprint server medRxiv in May 2020 analyses the data on the impact of COVID-19 on pregnancy and disease outcomes, using published cases of pregnant women diagnosed with the illness.

4 May 2020

Research detects a more dangerous SARS-CoV-2 mutation

A new study published on the preprint server bioRxiv in May 2020 reports the setting up of a system to help track new mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is behind the current COVID-19 pandemic. This will help analyze mutations to find and track the spread of those that are most likely to increase the pathogenicity of the virus, either by making it easier to transmit or by enhancing its resistance to treatment.

4 May 2020

Rapid affordable viral testing kits for low-resource settings

A new paper published on the preprint server bioRxiv* in April 2020 reports a low-cost, sensitive and rapid RT-PCR testing kit for the detection of COVID-19. If validated, this could provide an enormous boost to diagnostic testing in low-resource regions of the world.

4 May 2020

Low molecular weight heparins inhibit SARS-CoV-2 cell invasion

A recent paper available on the preprint server bioRxiv* reports preliminary data on the ability of low molecular weight heparins to interact with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), elicit structural changes in its key proteins and subsequently halt cell invasion.

3 May 2020

COVID-19 transmission model shows social distancing was effective in China

Most countries are at a standstill, with social distancing and physical distancing measures in place to reduce the spread of the novel coronavirus. Now, a new transmission model of the coronavirus disease (COVID-19) confirms that social distancing measures were effective in Wuhan City, the epicenter of the coronavirus pandemic, and Shanghai in China.

1 May 2020

COVID-19 lockdown affecting UK adult mental health

As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) took a firmer hold on the UK, the government introduced a lockdown on March 24, 2020, in an all-out attempt to ‘flatten the curve’ of infections. While the number of deaths has fallen in response, a new study published in the journal medRxiv in April 2020 reports that the pandemic is also associated with increased anxiety and depression in UK adults experiencing isolation.

30 Apr 2020

Spike protein analysis from India's first SARS-CoV-2

A new study published on the preprint server bioRxiv analyzes viral spike protein sequences from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in West Bengal, India, comparing them with sequences from other Indian states and Wuhan, China.

30 Apr 2020

Scientists generate molecular models of compounds relevant for COVID-19

The discovery of suitable drugs that could help treat diseases is a long process. However, computer-aided drug design and simulation could speed up the process and also increase the possibilities say experts. This form of drug design and simulation could soon be the gold standard in drug development.

30 Apr 2020

New database catalogs peptides that may halt SARS-CoV-2 cell infection

In the quest for a highly specific and tailored treatment strategy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a recent publication available on the preprint server bioRxiv describes a repository of designed peptides that interfere with the early stages of viral invasion process.

30 Apr 2020

Testing sewage could be useful in monitoring COVID-19 circulation in the population

Researchers in Italy have demonstrated the potential value of sewage system monitoring for studying trends in the circulation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

30 Apr 2020

Temple University Hospital is offering COVID-19 clinical trials, investigational treatments options

Temple University Hospital is now participating in a variety of clinical trials that are testing investigational treatment options for patients diagnosed with the novel coronavirus, or COVID-19.

30 Apr 2020

Remdesivir shows powerful activity against SARS-CoV-2 in Vitro

Remdesivir is an antiviral first developed by Gilead in 2014 as a treatment for Ebola and Marburg viruses. However, scientists explored its possibilities as a broad-spectrum drug when it proved effective against SARS-CoV and MERS-CoV, coronaviruses which were responsible for earlier outbreaks.

30 Apr 2020

Online searches for unproven therapies for COVID-19

A new observational study by a group of scientists explores the rise in the public's fear-driven interest in unproven therapies for COVID-19, particularly chloroquine and hydroxychloroquine, by tracking the internet searches relating to the purchase of drugs in news reports or publicized by public figures. They conclude: "Stay grounded in evidence and fight misinformation." The research letter and accompanying editorial comment are published in the journal JAMA Internal Medicine.

29 Apr 2020

Further evidence 'pooling of samples' for SARS-CoV-2 helps boost testing capacity

One of the problems faced by health officials today is the vast number of asymptomatic carriers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as they can still transmit the virus. Therefore the testing of as many people as possible is crucial for immediate isolation of cases to prevent the virus from spreading further.

29 Apr 2020

Australian COVID-19 vaccine candidate shows protective response in pre-clinical trials

Amid the coronavirus pandemic, scientists race to develop a vaccine that can help contain the spread of the virus. The coronavirus disease (COVID-19) has so far infected more than 3.18 million people across the globe. Now, early tests of a potential coronavirus vaccine have shown promise in pre-clinical trials.

29 Apr 2020

Coronaviruses represent a source of pandemic viruses

In a new paper published on the preprint journal bioRxiv in April 2020, researcher T. Konishi argues that the coronavirus family is a constellation of pandemic pathogens, that includes the currently spreading severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

29 Apr 2020

Low levels of vitamin D may be linked to severe COVID-19

A new observational study from the United States indicates that vitamin D insufficiency may play a significant role in the progression of coronavirus disease (COVID-19). The research titled 'Vitamin D Insufficiency is Prevalent in Severe COVID-19' is available on the preprint server medRxiv.Study shows that low levels of vitamin D may be linked to severe COVID-19

29 Apr 2020