Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Low CD8 and NK cell counts in the lung linked to high SARS-CoV-2 ACE2 receptor levels

A new study published on the preprint server bioRxiv in April 2020 reports that low levels of specific immune cells, namely, CD8 T cells and NK cells, are linked to higher expression of the ACE2 molecule, which acts as a receptor for the CoV.

6 May 2020

How do betacoronaviruses evolve?

Researchers have worked on the evolution of the pathogenic strains of the betacoronaviruses including the SARS CoV-2 that has caused the COVID-19 pandemic.

6 May 2020

Research looks at best ways to disinfect N95 masks for reuse

The world is gripped by the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The health care personnel and those caring for these patients are at considerable risk of contracting the infection. N95 masks have been mentioned as protective face gear to cover the face, nose, and mouth of the user to prevent the spread of the infection via aerosols generated while coughing, sneezing, or even breathing.

6 May 2020

Spillover of more bat coronaviruses likely due to destruction of wildlife habitats

A new study available on the preprint server bioRxiv used phylogenetic analysis to demonstrate how certain groups of bats harbor multiple coronavirus lineages that are not readily transmitted across different bat taxa. However, the researchers caution that another novel human coronavirus outbreak originating from bats is imminent due to the destruction of wildlife habitats.

6 May 2020

Study points towards the potential spread of COVID-19 via sewage

Environmental biologists at the University of Stirling have warned that the potential spread of COVID-19 via sewage "must not be neglected" in the battle to protect human health.

6 May 2020

PPE combined with proper training can reduce COVID-19 risk in health care workers

Health care workers carry a significant burden of coronavirus infections worldwide, but a new evidence review by researchers at Oregon Health & Science University shows the rate can be lowered with the use of personal protective equipment combined with proper training in infection control.

6 May 2020

Australia to ease restrictions with coronavirus app, return to work to kickstart the economy

Among the countries that have successfully “flattened the curve” and managed to contain the coronavirus, is Australia. The country has managed to keep the viral transmission at bay and has now lifted some restrictions to let its residents return to more normal lives. Along with easing restrictions, the Australian Government launched the COVIDsafe app to help speed up contacting people infected with the virus.

6 May 2020

Is ACEI, ARB use linked to testing positive for COVID-19?

A new study published in the prestigious journal JAMA Cardiology in May 2020 reports that there is no association between the use of ACEIs/ARBs and testing positive for COVID-19. This supports current medical advice to continue using these drugs as indicated irrespective of the ongoing pandemic but indicates the need for more research to rule out any additional risk of severe illness due to these agents.

6 May 2020

Study provides evidence for safety and efficacy of chloroquine in COVID-19

After a pilot study (Huang et al.Journal of Molecular Cell Biology, in press), having proved the safety and effectiveness of the drug to reduce the viral RNA to undetectable levels in 10 COVID-19 patients, the researchers began this current study, published on the preprint server medRxiv.

5 May 2020

Israeli scientists discover monoclonal antibody that neutralizes SARS-CoV-2

Now, in a significant medical breakthrough, Israel's Institute for Biological Research Institute (IIBRI) has wrapped up the development of a potential treatment for the coronavirus disease. The scientists say they have identified an antibody that neutralizes SARS-CoV-2.

5 May 2020

First French COVID-19 case was in December 19

The coronavirus disease (COVID-19), formerly known as the novel coronavirus infection, was first reported in late December 2019 in Wuhan City in China. Many health experts believe that the virus had spread way before it was identified as the culprit for many pneumonia-like diseases. Now, a French doctor says that the coronavirus reached France back in December when it admitted a pneumonia patient into hospital.

5 May 2020

SARS-CoV-2 genome shows mutation hotspots and type-specific distribution

Now, a new study published on the preprint server bioRxiv reports on a large scale analysis of SARS-CoV-2 genomes and reveals a clonal geo-distribution and rich genetic variations.

5 May 2020

COVID-19 and exposure to air pollution

A scientist from the Netherlands has worked on a study that looked at the association between COVID-19 infections and exposure to air pollution. Researcher Bo Pieter Johannes Andrée’s study titled “Incidence of COVID-19 and Connections with Air Pollution Exposure Evidence from the Netherlands” was released prior to the peer review process on the online server Medrxiv.

5 May 2020

Shortages of PPE for healthcare workers could be tackled using social media and 3D printing

Researchers have come up with the use of social media and 3D printing techniques to deal with the severe shortage of personal protective equipment (PPEs) for healthcare workers who are dealing with the highly infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The

5 May 2020

COVID-19 infection risk and outcomes explained by the cell receptor genetic variability

Genetic variants in the angiotensin‐converting enzyme 2 (ACE2) receptor, utilized by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) for cell entry, are predicted to either encourage or inhibit interaction with viral proteins and subsequently contribute to genetic risk in coronavirus disease (COVID-19). This is the key finding of a new study available on the preprint server bioRxiv*.

5 May 2020

Cat coronavirus drug shows promise for treatment of COVID-19

“They are strong drug candidates for the treatment of human coronavirus infections because they have already been successful in animals (cats),” writes the team. “The work here lays the framework for their use in human trials for the treatment of COVID-19.”

5 May 2020

Hydroxychloroquine shown to slow recovery for COVID-19 patients

As researchers try to piece together a therapeutic strategy against the ongoing COVID-19 pandemic, a recent retrospective study from Cleveland Clinic Abu Dhabi, assessed the Hydroxychloroquine's efficacy in increasing SARS-CoV-2 viral clearance, finding that it appeared to significantly slow viral clearance in mild to moderately ill COVID-19 patients.

5 May 2020

Loss of smell may be related to neuroinvasive propensity of SARS-CoV-2

The novel coronavirus has rapidly infected millions over the world in over 187 countries and territories, causing hundreds of thousands of deaths. One of the often-neglected and under-reported symptoms of the virus is the loss of the sense of smell or anosmia. Now, a new study out of Germany published on the preprint server medRxiv in April 2020 provides a quantified estimate of the magnitude of anosmia as a symptom of the coronavirus.

4 May 2020

Uncovering immune cell reactions in COVID-19

A new study published on the preprint server medRxiv in April 2020 suggests that an overactive immune response is responsible for the more severe manifestations of the illness.

4 May 2020

Asymptomatic carriers transmit SARS-CoV-2 with normal breathing

The coronavirus disease (COVID-19) first emerged in a seafood market in Wuhan City, Hubei Province, China, in December 2019. Since then, it has spread to 187 countries, infecting more than 3.58 million people. The novel coronavirus spreads rapidly partly due to asymptomatic carriers. Now a new study shows that asymptomatic carriers may transmit the virus by merely breathing.

4 May 2020