Sickle Cell Anemia News and Research

Latest Sickle Cell Anemia News and Research

New research changes the paradigm of how people think about graft-versus-host disease

New research challenges the prevailing hypothesis for how donor stem cell grafts cause graft-versus-host disease, or GVHD, and offers an alternative model that could guide development of novel therapies.

30 Jan 2023

AI tool promises to accelerate the development of gene therapies on a large scale

An artificial intelligence (AI) program may enable the first simple production of customizable proteins called zinc fingers to treat diseases by turning genes on and off.

26 Jan 2023

Newly discovered CRISPR immune system shuts down infected cells to thwart infection

In this interview, News Medical speaks to Assitant Professor Ryan Jackson about his latest work, published in tandem Nature papers, detailing the discovery of a new CRISPR immune system.

11 Jan 2023

Protection afforded by SARS-CoV-2 infection against reinfection when Omicron BA.5 was the dominating subvariant in Scania county, Sweden

Researchers from Sweden conducted a cohort study to evaluate the protection granted by previous SARS-CoV-2 Omicron subvariant infections against reinfections among individuals vaccinated between June and August 2022.

17 Nov 2022

First transfusions of lab-grown blood

Two patients in the United Kingdom received two small doses of lab-grown blood samples as part of the RESTORE trial.

9 Nov 2022

Report: Less than half of children with sickle cell anemia received recommended screening and treatment

In 2019, less than half of children aged 2–16 years with sickle cell anemia received the recommended screening for stroke, a common complication of the disease, according to a new CDC Vital Signs report.

27 Sep 2022

Supplementary folic acid associated with higher risk of COVID-19 diagnosis and mortality

In a recent study published in the journal BMJ Open, researchers investigated the impact of folic acid supplements and methotrexate, in combination or individually, on disease severity and mortality in coronavirus disease 2019 (COVID-19) cases.

8 Sep 2022

Carbon monoxide foam in the fight against inflammation

News-Medical speaks to Leo Otterbein about a novel way to deliver carbon monoxide to the body while bypassing its potentially hazardous effects.

2 Aug 2022

Efficacy of vaccination against SARS-CoV-2 Omicron BA.1 and BA.2 sublineages in Sweden

Researchers compared the vaccine effectiveness against infections by SARS-CoV-2 variant of concern Omicron BA.1 and BA.2 sublineages in Sweden.

22 Apr 2022

Researchers develop universal AI algorithm to "clean" noisy single-cell RNA sequencing data

Just as asking a single person about their health will provide tailored, personalized information impossible to glean from a large poll, an individual cell's genome or transcriptome can provide much more information about their place in living systems than sequencing a whole batch of cells.

7 Apr 2022

Researchers reveal unique signature of genes expressed by hematopoietic stem cells

Hematopoietic stem cells (HSCs) have the capacity to both self-renew and differentiate into all mature blood cell types, making them promising treatments for a variety of diseases.

2 Mar 2022

Drugs that increase fetal hemoglobin levels may help people with sickle cell disease

Sickle cell anemia is an inherited blood disorder where red blood cells become sickle/crescent shaped. It causes frequent infections, swelling in the hands and legs, pain, severe tiredness and delayed growth or puberty.

18 Feb 2022

New method of stem cell transplantation may eliminate the need for radiation or chemotherapy

Studying mice, researchers at Washington University School of Medicine in St. Louis have developed a method of stem cell transplantation that does not require radiation or chemotherapy.

10 Nov 2021

Lehigh’s undergraduate students receive NIH Award for new sickle cell diagnostic device

Their tickets were booked. Their schedules were set. The students were finally going to test their product on real people. But in July, Sierra Leone's COVID-19 level spiked almost overnight, and Lehigh's Sickle Cell Anemia Diagnostic Device team lost yet another opportunity to conduct fieldwork.

1 Nov 2021

Hydroxyurea therapy can improve or reverse cardiac complications in sickle cell anemia patients

Heart abnormalities are common complications of sickle cell anemia (SCA) that can contribute to severe disease symptoms and even death.

16 Sep 2021

UB scientists publish a detailed guide for producing mature human cells in a mouse embryo

A year after University at Buffalo scientists demonstrated that it was possible to produce millions of mature human cells in a mouse embryo, they have published a detailed description of the method so that other laboratories can do it, too.

2 Jul 2021

Researchers develop proof-of-concept treatment for blood disorders

Researchers at Children's Hospital of Philadelphia (CHOP) have developed a proof-of-concept treatment for blood disorders like sickle cell disease and beta-thalassemia that could raise hemoglobin levels by activating production of both fetal and adult hemoglobin.

1 Jun 2021

Novel approach to gene editing bypasses disease-causing mutations in a gene

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

21 Apr 2021

Research may lead to a significant breakthrough in the battle against deadly brain tumors

Groundbreaking research from Tel Aviv University may lead to a significant breakthrough in the battle against deadly brain cancer.

12 Apr 2021

'Miracle poison' can target a variety of different proteins

Researchers prove they can engineer proteins called proteases to find new targets with high selectivity, a critical advance toward potential new treatments for everything from neuro-regeneration to cytokine storm.

25 Feb 2021

Sickle Cell Anemia News and Research

Latest Sickle Cell Anemia News and Research

New research changes the paradigm of how people think about graft-versus-host disease

AI tool promises to accelerate the development of gene therapies on a large scale

Newly discovered CRISPR immune system shuts down infected cells to thwart infection

Protection afforded by SARS-CoV-2 infection against reinfection when Omicron BA.5 was the dominating subvariant in Scania county, Sweden

First transfusions of lab-grown blood

Report: Less than half of children with sickle cell anemia received recommended screening and treatment

Supplementary folic acid associated with higher risk of COVID-19 diagnosis and mortality

Carbon monoxide foam in the fight against inflammation

Efficacy of vaccination against SARS-CoV-2 Omicron BA.1 and BA.2 sublineages in Sweden

Researchers develop universal AI algorithm to "clean" noisy single-cell RNA sequencing data

Researchers reveal unique signature of genes expressed by hematopoietic stem cells

Drugs that increase fetal hemoglobin levels may help people with sickle cell disease

New method of stem cell transplantation may eliminate the need for radiation or chemotherapy

Lehigh’s undergraduate students receive NIH Award for new sickle cell diagnostic device

Hydroxyurea therapy can improve or reverse cardiac complications in sickle cell anemia patients

UB scientists publish a detailed guide for producing mature human cells in a mouse embryo

Researchers develop proof-of-concept treatment for blood disorders

Novel approach to gene editing bypasses disease-causing mutations in a gene

Research may lead to a significant breakthrough in the battle against deadly brain tumors

'Miracle poison' can target a variety of different proteins

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Sickle Cell Anemia News and Research

Latest Sickle Cell Anemia News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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