Sickle Cell Anemia News and Research

Latest Sickle Cell Anemia News and Research

New enzyme may one day enable genome surgery that erases harmful mutations

DNA editing just got a sharp, new pencil. Researchers have built an enzyme that can perform a previously impossible DNA swap, directly changing the DNA base pair from an A•T to a G•C.

26 Oct 2017

Metabolism can impact host's susceptibility to develop malaria

Researchers from Instituto de Medicina Molecular Lisboa have found that the host's susceptibility to develop malaria depends on his or her metabolic state, which can be easily manipulated through external stimuli such as dietary patterns.

25 Sep 2017

Expert highlights CRISPR’s applications, limitations, and ethical concerns

"Good morning, doctor, I am here for my gene editing appointment." In the future, could this be a greeting heard in physician offices around the world? With the introduction of CRISPR technology, genetic material can now be more easily and precisely edited, even creating changes that can subsequently be inherited by offspring.

1 Aug 2017

New genomic research partnership promises to redefine and transform cancer treatment

Personalized cancer therapies are on the horizon thanks to a new genomic cancer research partnership between the Gene Editing Institute of Christiana Care Health System's Helen F. Graham Cancer Center & Research Institute and the biotechnology company NovellusDx.

21 Jul 2017

'Organic gene therapy' could be effective treatment approach for serious blood disorders

Genome therapy with beneficial natural mutation could lead to new treatment for life-threatening blood disorders.

17 Jul 2017

MSU researcher developing new miniature models to study heart disease and sickle cell anemia

A Mississippi State University researcher is developing new miniature models to better understand the factors that lead to heart disease and sickle cell anemia.

24 Jun 2017

Americord introduces Digital Birth Plan to help expectant parents make informed choices

Americord, the fastest growing cord blood bank in the country, and a leader in umbilical cord blood, cord tissue, and placental tissue banking announces the launch of its Digital Birth Plan.

2 Jun 2017

Researchers discover innovative way to produce hematopoietic stem cells

A study published on May 17 in Nature, discovers an innovative method to produce infinite supply of healthy blood cells from the readily available cells that line blood vessels. This achievement by the researchers at Weill Cornell Medicine marks the first time that any research group has generated such blood-forming stem cells.

18 May 2017

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

A team led by Pr. Marina Cavazzana conducted at Necker Children's Hospital, AP-HP and the Imagine Institute in October 2014 gene therapy in the context of a phase I clinical trial / II in a patient 13 years with severe sickle cell disease.

2 Mar 2017

Upstate opens new public cord blood bank in New York

Upstate Medical University opens the Upstate Cord Blood Bank, only the second public cord blood bank in New York and one of only 32 in the US.

20 Feb 2017

Yale researchers use new gene editing technique to correct mutations that cause thalassemia

A Yale-led research team used a new gene editing strategy to correct mutations that cause thalassemia, a form of anemia.

26 Oct 2016

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of affected patients.

12 Oct 2016

New study finds no evidence of benefit from genetic disposition of eczema

Some genetic diseases persist for generation after generation because the genes that cause them can benefit human health.

6 Oct 2016

New mobile health app may help manage hydroxyurea treatments in sickle cell patients

The National Heart, Lung, and Blood Institute, part of the National Institutes of Health, has awarded a 6-year, $4.4 million grant to St. Jude Children's Research Hospital and collaborators to improve the use of prescribed medication by sickle cell patients.

21 Sep 2016

Scientists link malfunctioning molecular pathways to specific heart abnormalities in SCA

Patients with sickle cell anemia (SCA) develop heart complications and nearly a quarter die a sudden death. Now, researchers have linked malfunctioning molecular pathways to specific heart anomalies in SCA that result from progressive fibrosis and result in sudden death.

9 Aug 2016

New computer model shows how spleen filters misshapen red blood cells

Researchers, led by Carnegie Mellon University President Subra Suresh and MIT Principal Research Scientist Ming Dao, have created a new computer model that shows how tiny slits in the spleen prevent old, diseased or misshapen red blood cells from re-entering the bloodstream.

28 Jun 2016

Scientists develop non-toxic transplantation procedure using antibodies to target blood stem cells in mice

Harvard Stem Cell Institute scientists have taken the first steps toward developing a treatment that would make bone marrow - blood stem cell - transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and AIDS.

7 Jun 2016

Minihepcidins may potentially treat serious genetic blood diseases in children, adults

New research suggests that synthetic peptides called minihepcidins may potentially treat two serious genetic blood diseases in children and adults. Although those diseases, beta-thalassemia and polycythemia vera, have opposite effects on red blood cell production, treating animals with minihepcidin helps to restore normal levels of red blood cells and reduces spleen enlargement. It also controls the accumulation of excess levels of iron in beta-thalassemia that often causes severe toxic effects.

9 May 2016

Inhalable form of Ambrisentan drug could offer faster-acting treatment option for pulmonary edema

In a new study, researchers show an aerosolized, inhalable form of the drug Ambrisentan could offer a faster-acting treatment option for pulmonary edema, a life-threatening condition in which fluid accumulates in the lungs. Pulmonary edema is a significant risk for anyone spending time at high altitudes, and also affects people with chronic conditions including congestive heart failure and sickle cell anemia.

5 Apr 2016

Three Case Western faculty members receive funding to develop new diagnostic technologies

Three Case Western Reserve University faculty members have received funding to further develop emerging technologies aimed at malaria, cystic fibrosis, and sickle cell anemia.

29 Jan 2016

Sickle Cell Anemia News and Research

Latest Sickle Cell Anemia News and Research

New enzyme may one day enable genome surgery that erases harmful mutations

Metabolism can impact host's susceptibility to develop malaria

Expert highlights CRISPR’s applications, limitations, and ethical concerns

New genomic research partnership promises to redefine and transform cancer treatment

'Organic gene therapy' could be effective treatment approach for serious blood disorders

MSU researcher developing new miniature models to study heart disease and sickle cell anemia

Americord introduces Digital Birth Plan to help expectant parents make informed choices

Researchers discover innovative way to produce hematopoietic stem cells

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

Upstate opens new public cord blood bank in New York

Yale researchers use new gene editing technique to correct mutations that cause thalassemia

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

New study finds no evidence of benefit from genetic disposition of eczema

New mobile health app may help manage hydroxyurea treatments in sickle cell patients

Scientists link malfunctioning molecular pathways to specific heart abnormalities in SCA

New computer model shows how spleen filters misshapen red blood cells

Scientists develop non-toxic transplantation procedure using antibodies to target blood stem cells in mice

Minihepcidins may potentially treat serious genetic blood diseases in children, adults

Inhalable form of Ambrisentan drug could offer faster-acting treatment option for pulmonary edema

Three Case Western faculty members receive funding to develop new diagnostic technologies

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Sickle Cell Anemia News and Research

Latest Sickle Cell Anemia News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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