Sickle Cell Anemia News and Research

Latest Sickle Cell Anemia News and Research

New gene therapy cures babies with fatal 'Bubble Boy' disease

A new gene therapy created by US researchers appears to have cured eight infant boys born with a rare genetic disorder referred to as “Bubble Boy” disease.

18 Apr 2019

Cancer patients and those with anemia should not be denied opioids, says CDC

The U.S. CDC has issued a letter clarifying that people suffering from severe pain caused by cancer or sickle-cell anemia should not be denied prescriptions for opioid pain-killers.

11 Apr 2019

Deadly inherited blood disorders cured with bone marrow transplant

Doubling the low amount of total body radiation delivered to patients undergoing bone marrow transplants with donor cells that are only "half-matched" increased the rate of engraftment from only about 50 percent to nearly 100 percent, according to a new study by Johns Hopkins researchers.

15 Mar 2019

Research shows how common fungus gets the flexibility to live in different host environments

The fungus Candida albicans is found in the gastrointestinal tract of about half of healthy adults with little if any effect, yet it also causes an oft-fatal blood infection among patients with compromised immune systems, including those with HIV/AIDS.

1 Mar 2019

Antibody-based treatment could improve cure rate for blood and immune disorders

An antibody-based treatment can gently and effectively eliminate diseased blood-forming stem cells in the bone marrow to prepare for the transplantation of healthy stem cells, according to a study in mice by researchers at the Stanford University School of Medicine.

12 Feb 2019

Advances in gene therapy for inherited blood disorders

Gene therapy holds a lot of promise in medicine. If we could safely alter our own DNA, we might eliminate diseases our ancestors passed down to us.

4 Dec 2018

New gene therapy treatment for Sickle Cell Anemia reverses symptoms in adults

After over a decade of preclinical research and development, a new gene therapy treatment for Sickle Cell Anemia is reversing disease symptoms in two adults and showing early potential for transportability to resource-challenged parts of the world where SCA is most common.

3 Dec 2018

Daily hydroxyurea treatment may bring some relief for African children with sickle cell anemia

A daily hydroxyurea pill may finally bring some relief for young children living with the painful and deadly blood disease sickle cell anemia in resource-challenged sub-Saharan Africa, where the disease is prevalent and health care availability is suboptimal.

3 Dec 2018

Johns Hopkins researchers report challenges in treating severe crisis pain of sickle cell disease

In a study tracking the severe crisis pain of sickle cell disease and its management in 73 adults over a period of a year, Johns Hopkins researchers found that even among those on high doses of daily at-home opioids, a persistent subset was more likely to seek emergency hospital care for crisis pain and was less likely to have the pain controlled by intensive treatment.

27 Nov 2018

Scientists find people's assumptions about DNA repair after CRISPR editing to be wrong

Despite high hopes and high investment in CRISPR-Cas9 gene editing, scientists still have a lot to learn about how it works in humans.

31 Jul 2018

Therapy with L-Glutamine reduces pain in patients with sickle cell disease

UCSF Benioff Children's Hospital Oakland clinical researchers, in conjunction with other sickle cell centers and scientists at Emmaus Life Sciences, Inc., have demonstrated that therapy with L-Glutamine reduced the frequency of pain episodes in both pediatric and adult patients with sickle cell disease.

27 Jul 2018

CRISPR-Cas9 technique may raise cancer risk

Therapeutic use of gene editing with the so-called CRISPR-Cas9 technique may inadvertently increase the risk of cancer, according to a new study from Karolinska Institutet, Sweden, and the University of Helsinki, Finland, published in Nature Medicine.

11 Jun 2018

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

Scientists at Christiana Care Health System's Gene Editing Institute have developed a potentially breakthrough CRISPR gene-editing tool. It could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and quickly and precisely engineer multiple changes to the genetic code, according to a new study published today in the CRISPR Journal.

20 Apr 2018

New discovery may offer insight into treating sickle cell anemia and other blood disorders

Discovery by Scripps Research scientists may offer insight into treating blood disorders such as sickle cell anemia.

4 Apr 2018

Human genome is like a time machine, says researcher

The human genome is a bit like a time machine, says Ben Voight, an associate professor in Systems Pharmacology and Translational Therapeutics and of Genetics in Penn's Perelman School of Medicine.

3 Apr 2018

Study: Most children with sickle cell anemia not getting daily antibiotics to reduce the risk

One of the greatest health threats to children with sickle cell anemia is getting a dangerous bacterial infection - but most are not receiving a key medication to reduce the risk, a new study suggests.

13 Feb 2018

Company-sponsored CRISPR clinical studies to begin in 2018

This year could be a defining one for CRISPR, the gene editing technique, which has been hailed as an important breakthrough in laboratory research.

10 Jan 2018

Increasing hydroxyurea dose linked to reduction in hospitalization for young sickle cell anemia patients

St. Jude Children's Research Hospital investigators have shown that using the drug hydroxyurea to boost average fetal hemoglobin levels above 20 percent in children and teenagers with sickle cell anemia was associated with at least a two-fold reduction in hospitalization for any reason.

9 Nov 2017

Sickle cell patients suffer discrimination, poor care — and shorter lives

For more than a year, NeDina Brocks-Capla avoided one room in her large, brightly colored San Francisco house — the bathroom on the second floor.

6 Nov 2017

Conference to focus on preventing and reversing consequences of sickle cell disease

Leading experts in the field of sickle cell disease (SCD) research will convene in Washington, D.C., for the Physiological and Pathophysiological Consequences of Sickle Cell Disease conference (November 6–8). The conference, organized by the American Physiological Society, will explore SCD- the world's most prevalent single-gene mutation disease-; and new research on preventing and reversing its deadly consequences.

1 Nov 2017

Sickle Cell Anemia News and Research

Latest Sickle Cell Anemia News and Research

New gene therapy cures babies with fatal 'Bubble Boy' disease

Cancer patients and those with anemia should not be denied opioids, says CDC

Deadly inherited blood disorders cured with bone marrow transplant

Research shows how common fungus gets the flexibility to live in different host environments

Antibody-based treatment could improve cure rate for blood and immune disorders

Advances in gene therapy for inherited blood disorders

New gene therapy treatment for Sickle Cell Anemia reverses symptoms in adults

Daily hydroxyurea treatment may bring some relief for African children with sickle cell anemia

Johns Hopkins researchers report challenges in treating severe crisis pain of sickle cell disease

Scientists find people's assumptions about DNA repair after CRISPR editing to be wrong

Therapy with L-Glutamine reduces pain in patients with sickle cell disease

CRISPR-Cas9 technique may raise cancer risk

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

New discovery may offer insight into treating sickle cell anemia and other blood disorders

Human genome is like a time machine, says researcher

Study: Most children with sickle cell anemia not getting daily antibiotics to reduce the risk

Company-sponsored CRISPR clinical studies to begin in 2018

Increasing hydroxyurea dose linked to reduction in hospitalization for young sickle cell anemia patients

Sickle cell patients suffer discrimination, poor care — and shorter lives

Conference to focus on preventing and reversing consequences of sickle cell disease

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Sickle Cell Anemia News and Research

Latest Sickle Cell Anemia News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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