Sickle Cell Anemia News and Research

Latest Sickle Cell Anemia News and Research

Study: TALEN is five times more efficient than CRISPR-Cas9 in tightly packed DNA

Researchers used single-molecule imaging to compare the genome-editing tools CRISPR-Cas9 and TALEN.

27 Jan 2021

New method could help determine the most appropriate treatment for HIV patients

A team co-led by a scientist at the University of California, Riverside, has developed a method to study how HIV mutates to escape the immune system in multiple individuals, which could inform HIV vaccine design.

30 Nov 2020

New procedure offers lasting pain relief for patients with osteoarthritis

A novel outpatient procedure offers lasting pain relief for patients suffering from moderate to severe arthritis in their hip and shoulder joints, according to a study presented at the annual meeting of the Radiological Society of North America (RSNA).

16 Nov 2020

Study finds more effective treatment for children with sickle cell anemia

A team of international researchers has learned that dose escalation of hydroxyurea treatment for children in Uganda with sickle cell anemia is more effective and has similar side effects than a lower fixed dose of the same drug.

25 Jun 2020

Researchers treat TMC1-related deafness with gene therapy

When Wei Hsi (Ariel) Yeh was a young undergraduate student, one of her close friends went from normal hearing to complete deafness in the span of one month.

4 Jun 2020

Study explores whether senicapoc drug can mitigate lung damage in COVID-19 patients

Scientists around the globe are working to identify approved and investigational drugs that can be repurposed to treat COVID-19.

13 May 2020

Gene-editing taken to advanced levels in human stem cells

A new study published in the journal Stem Cell Reports in January 2020 reports the use of an adaptation to a commonly used gene editing technology to achieve a more than 900% increase in efficiency.

30 Jan 2020

3D capillary system offers a new approach to investigate obstruction of microvessels

Engineered human capillaries are providing an astounding view of how red blood cells transit ultra-small blood vessels.

23 Jan 2020

Horizon Discovery to offer novel base editing technology for clinical research

Horizon Discovery today announced that it will provide access to a novel base editing technology licensed from Rutgers for exclusive use in therapeutic, diagnostic and services applications.

From Revvity 14 Jan 2020

Using CRISPR to switch off pain gene becomes a possibility with new study

A pathbreaking study reports success in disabling an important gene that is responsible for inducing the sensation of pain.

7 Jan 2020

Scientists develop 3D atlas of bone marrow to help study blood diseases

The bone marrow, which is the spongy and viscous tissue that fills the bone, is the site of blood cell formation or hematopoiesis. If the bone marrow doesn’t work properly, it can lead to many blood diseases, including leukemia, sickle cell anemia, and lymphoma, among others.

23 Dec 2019

Prenatal screening for hemoglobinopathies different in OBGYN practices and family medicine

Sickle cell disease is one of the most common inherited red blood cell disorders, yet many are not aware of their carrier status (Treadwell, J Nat Med Assoc, 2006), which can lead to confusion around pregnancy and newborn diagnosis.

5 Dec 2019

Adding plant-based compound to gene therapy could improve treatment outcomes

Gene therapy has broadened the treatment possibilities for those with immune system deficiencies and blood-based conditions, such as sickle cell anemia and leukemia.

17 Oct 2019

CDC to fund sickle cell disease surveillance

The Centers for Disease Control and Prevention (CDC) has announced a funding of $1.2 million to different states in order to collect data and information from people suffering from sickle cell disease. The program called the Sickle Cell Data Collection program or SCDC is at present functional in two states - California and Georgia. With the new funds coming in, nine states would be able to collect and send population based information on the health of persons living with sickle cell disease.

27 Sep 2019

Researcher aims to make CRISPR-Cas9 system safer and more precise

The mere mention of gene editing and DNA altering might conjure up images of designer babies, but that is not what researcher Jin Liu has in mind.

26 Sep 2019

Researchers develop new way to measure how mechanical fatigue affects biological cells

Human red blood cells are extremely resilient and have the capacity to undergo cellular deformation as they navigate across various micro-vessels and capillaries.

17 Sep 2019

First ever American gene-editing treatment using CRISPR for genetic disease

In a pathbreaking experiment, a 34-year-old mother of four from Mississippi is in the limelight for volunteering to be the subject of CRISPR-mediated gene editing in the hope of achieving a cure for the painful sickle cell anemia with which she has suffered all her life.

30 Jul 2019

Single-cell encapsulation technology can protect transplanted MSCs from immune attack

Bone marrow transplants of hematopoietic stem cells have become standard treatment for a host of conditions including cancers of the blood and lymphatic systems, sickle cell anemia, inherited metabolic disorders, and radiation damage.

16 Jul 2019

Three signs of real progress against sickle cell disease

A decade ago, the United Nations declared June 19 to be World Sickle Cell Awareness Day- and for good reason.

19 Jun 2019

More screening and new treatments needed for sickle cell disease

The promise of new treatments for sickle cell disease, a group of inherited red blood cell disorders, has never been so great, but it will only be realized if there is constant investment in health policies such as programs for screening newborns, especially in sub-Saharan Africa, where most cases occur.

13 Jun 2019