T Cell News and Research

Latest T Cell News and Research

Antibody and T cell response to SARS-CoV-2 persist up to 8 months: Study of Ski Resort Ischgl

The first instance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in Austria was observed in the Ski resort Ischgl in early March 2020. Later, the virus spread across Austria and other countries in Northern Europe.

25 Feb 2021

Pre-existing cross-reactive HCoV antibodies could protect against SARS-CoV-2

A team of researchers from Spain and Canada recently characterized the antibody kinetics and neutralization capacity at 4 cross-sectional surveys between March and October 2020 and determined the seroprevalence in the same cohort of healthcare workers.

25 Feb 2021

Microbes could predict fatal outcomes in ventilated COVID-19 patients

The study "Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome" is available as a preprint on the medRxiv* server, while the article undergoes peer review.

25 Feb 2021

Scientists receive grant to investigate tumor development within a natural environment

Unlike many of us during the COVID-19 pandemic, biological cells are not isolated from the outside world. Chemical variations, intercellular activity, and other microenvironmental factors impact cell survival.

25 Feb 2021

CRISPR screen identifies clinically approved immunosuppressants that could treat coronavirus infections

Researchers in Switzerland and Germany have identified host cell factors required for coronavirus replication that could serve as targets for treatment with clinically-approved drugs.

25 Feb 2021

Study pinpoints potential transmission advantage of SARS-CoV-2 variant B.1.1.7

Researchers in the UK have shown that the increased transmissibility of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineage B.1.1.7 that emerged in the UK during the coronavirus disease 2019 (COVID-19) pandemic does not appear to be the result of increased viral replication or immune escape.

25 Feb 2021

Repetitive compression of limbs may improve recovery from the most deadly stroke

Scientists want to know more about how an inexpensive, low-risk treatment may improve recovery from the most deadly type of stroke.

25 Feb 2021

SARS-CoV-2 ORF7a mutation limits host immune suppression, finds study

Researchers have identified a high variability in the C-terminal end of ORF7a in SARS-CoV-2 sequences collected from around the globe. They noted that mutations result in a defective suppression of interferon and lowered replication rate.

25 Feb 2021

SNX-5422 could make an effective COVID-19 prophylactic, says study

SNX-5422 is a heat shock protein 90 (Hsp90) inhibitor currently undergoing clinical trials as a cancer therapeutic. A recent study examines the applicability of repurposing the drug towards severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication inhibition.

25 Feb 2021

Research shows effective strategy to target the SARS-CoV-2 spike protein

The virus that causes COVID-19 belongs to the family of coronaviruses, "corona" referring to the spikes on the viral surface. These spikes are not static-;to infect cells, they change shapes.

25 Feb 2021

Study reveals molecular details of SARS-CoV-2 interactions with human cells

In order to infect cells, SARS-CoV-2, the virus that causes COVID-19, needs to insert itself into the membrane of human cells. New molecular models show what parts of SARS-CoV-2 are critical for that interaction, revealing new potential drug targets.

25 Feb 2021

Study reports lasting immune response in convalescent COVID-19 patients

Researchers report the cellular immune response of convalescent patients in Germany, who recovered from mild or moderate infection compared to that of healthy people with no history of COVID-19.

25 Feb 2021

Neuroinvasiveness of SARS-CoV-2 shown by viral RNA and inflammation in the brain

A new study describes the results of a macaque study that showed the development of neurological features of inflammation, following infection by SARS-CoV-2.

25 Feb 2021

Study explores individual differences of SARS-CoV-2 infection in ACE2-expressing stem cells

The clinical phenotype of COVID-19, caused by SARS-CoV-2, is remarkable for its wide range of severity among individual patients. Genetic variations are known to mediate part of these differences. To examine these differences, researchers in a new study used human induced pluripotent stem cells (iPSCs) from different genetically diverse individuals. These cells are used to model genetic disease since they contain the donor’s genetic information. Researchers use a panel of iPSCs from over 500 individuals. The researchers preferred undifferentiated iPSCs to reduce the time required to differentiate them, especially since infection is not always reliable.

25 Feb 2021

New hydrogel-based materials show promise for tissue engineering

New hydrogel-based materials that can change shape in response to psychological stimuli, such as water, could be the next generation of materials used to bioengineer tissues and organs, according to a team of researchers at the University of Illinois Chicago.

25 Feb 2021

Insilico Medicine discovers novel preclinical candidate to address idiopathic pulmonary fibrosis

Insilico Medicine has demonstrated a breakthrough in Artificial Intelligence ("AI") and drug discovery -- linking together generative chemistry and biology for the first time -- to discover a novel preclinical candidate addressing idiopathic pulmonary fibrosis ("IPF") and be validated with multiple human cell and animal model experiments.

25 Feb 2021

Researchers discover specific blood biomarker that predicts kidney transplant rejection

Researchers at the University of Pittsburgh School of Medicine have discovered a blood biomarker that predicts kidney transplant rejection with a lead time of about eight months, which could give doctors an opportunity to intervene and prevent permanent damage.

25 Feb 2021

Study reveals key mechanism by which exercise promotes immunity, strengthens bones

Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) have identified the specialized environment, known as a niche, in the bone marrow where new bone and immune cells are produced.

25 Feb 2021

New study sheds light on specialized compartments exhibited by Earth's single-celled ancestors

Scientists have long speculated about the features that our long-ago single-celled ancestors might have had, and the order in which those features came about. Bubble-like compartments are a hallmark of the superkingdom to which we, and many other species including yeast, belong.

25 Feb 2021

Process of molecular sorting emerges from combination of two spontaneous mechanisms, indicates study

The eukaryotic cell is the basic unit of animals and plants. At the microscope, it looks highly structured and subdivided in many membrane-bound compartments.

25 Feb 2021

T Cell News and Research

Latest T Cell News and Research

Antibody and T cell response to SARS-CoV-2 persist up to 8 months: Study of Ski Resort Ischgl

Pre-existing cross-reactive HCoV antibodies could protect against SARS-CoV-2

Microbes could predict fatal outcomes in ventilated COVID-19 patients

Scientists receive grant to investigate tumor development within a natural environment

CRISPR screen identifies clinically approved immunosuppressants that could treat coronavirus infections

Study pinpoints potential transmission advantage of SARS-CoV-2 variant B.1.1.7

Repetitive compression of limbs may improve recovery from the most deadly stroke

SARS-CoV-2 ORF7a mutation limits host immune suppression, finds study

SNX-5422 could make an effective COVID-19 prophylactic, says study

Research shows effective strategy to target the SARS-CoV-2 spike protein

Study reveals molecular details of SARS-CoV-2 interactions with human cells

Study reports lasting immune response in convalescent COVID-19 patients

Neuroinvasiveness of SARS-CoV-2 shown by viral RNA and inflammation in the brain

Study explores individual differences of SARS-CoV-2 infection in ACE2-expressing stem cells

New hydrogel-based materials show promise for tissue engineering

Insilico Medicine discovers novel preclinical candidate to address idiopathic pulmonary fibrosis

Researchers discover specific blood biomarker that predicts kidney transplant rejection

Study reveals key mechanism by which exercise promotes immunity, strengthens bones

New study sheds light on specialized compartments exhibited by Earth's single-celled ancestors

Process of molecular sorting emerges from combination of two spontaneous mechanisms, indicates study

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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