T Cell News and Research

Latest T Cell News and Research

Modified version of CAR T-cell therapy shows promise in targeting neuroblastoma

Chimeric Antigen Receptor T-cell therapy--CAR T--has revolutionized leukemia treatment. Unfortunately, the therapy has not been effective for treating solid tumors including childhood cancers such as neuroblastoma.

22 Jan 2021

Researchers develop comprehensive framework to classify small-cell lung cancer

Researchers from The University of Texas MD Anderson Cancer Center have developed the first comprehensive framework to classify small-cell lung cancer (SCLC) into four unique subtypes, based on gene expression, and have identified potential therapeutic targets for each type in a study published today in Cancer Cell.

22 Jan 2021

New study helps understand molecular profile of tumors in cancer patients

Researchers from the University Hospitals in Zurich and Basel, ETH Zurich, University of Zurich and the pharmaceutical company Roche have set out to improve cancer diagnostics by developing a platform of state-of-the-art molecular biology methods.

21 Jan 2021

Mitochondrial mutation linked to elevated diabetes risk in Japanese men

A new study of Type 2 diabetes in Japanese populations has uncovered a previously uncharacterized genetic variant that puts male carriers at greater risk for the disease, as well as the mechanism by which it does so.

21 Jan 2021

Pfizer-BioNTech vaccine shows reduced neutralization potential against SARS-CoV-2 B.1.1.7 spike variant

Researchers in the UK have conducted a study assessing the efficacy of the Pfizer-BioNTech COVID-19 vaccine BNT162b2 against the new variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

21 Jan 2021

New drug target valid for breast cancer as well as lymphoma

One more piece of the puzzle has fallen into place behind a new drug whose anti-cancer potential was developed at the University of Alberta and is set to begin human trials this year, thanks to newly published research.

21 Jan 2021

SARS-CoV-2 suppresses host innate immunity

SARS-CoV-2, the virus that causes COVID-19, blocks the processes of innate immune activation that normally direct the production and/or signaling of type I interferon (IFN-I) by the infected cell and tissues.

21 Jan 2021

Researchers identify genetic risk factors contributing to pneumonia susceptibility and severity

Researchers at Vanderbilt University Medical Center and colleagues have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences.

21 Jan 2021

Investigational combo therapy shows promise in treating TP53 mutant MDS and AML patients

Myelodysplastic Syndromes (MDS) and acute myeloid leukemia (AML) are rare hematologic malignancies of the bone marrow.

21 Jan 2021

FDA approves first injectable, complete regimen for HIV-1 infection in adults

The U.S. Food and Drug Administration today approved Cabenuva (cabotegravir and rilpivirine, injectable formulation) as a complete regimen for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults to replace a current antiretroviral regimen in those who are virologically suppressed on a stable antiretroviral regimen with no history of treatment failure and with no known or suspected resistance to either cabotegravir or rilpivirine.

21 Jan 2021

Scientists identify a molecular mechanism that protects the fetus from maternal infection

Researchers at Duke and Mt. Sinai have identified a molecular mechanism that prevents a viral infection during a mother's pregnancy from harming her unborn baby.

21 Jan 2021

AACR and MPM award three grants to support groundbreaking cancer research projects

Three grants for research that could transform cancer therapies have been awarded by the AACR-MPM Oncology Charitable Foundation Transformative Cancer Research Grants Program, an innovative partnership between the American Association for Cancer Research and the UBS Oncology Impact Fund managed by MPM Capital.

21 Jan 2021

SU2C announces $3.25 million in grants to find new treatments for head and neck cancers

Stand Up To Cancer today announced $3.25 million in grants from four national nonprofits to fund research to find new treatments for head and neck cancers, which are newly diagnosed in about 65,000 Americans every year.

21 Jan 2021

A single genetic test can identify the presence and cause of mismatch repair deficiency

Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in colon, endometrial, and other cancers.

21 Jan 2021

Researchers use SARS-CoV-2 to bioengineer universal vaccine platform

Using SARS-CoV-2, a team of scientists from the United States has recently developed a bioengineered bacteriophage T4 nanoparticle structure using CRISPR technology that can be used as a universal platform to produce vaccines.

21 Jan 2021

New sensory neuron model enables easy generation of cells to fast-track pain research

Scientists have for the first time established a sensory neuron model able to mass-reproduce two key sensory neuron types involved in pain sensation, enabling the easy generation of large numbers of the cells to fast-track chronic pain research.

21 Jan 2021

High factor V levels linked to lymphopenia and weakened immunity in severe COVID-19

A new study suggests that factor V, a coagulation factor, is upregulated in a range of white blood cells in severe COVID-19. This increase is linked to the observed coagulopathy, lymphopenia and suppression of adaptive immunity in such patients.

21 Jan 2021

Blood group associated with cardiovascular events in COVID-19 patients

An illuminating new study by scientists at Harvard Medical School, USA, describes the correlation of such conditions with the ABO blood group. The team's findings may help assess the risk of COVID-19 patients for such complications, promoting early diagnosis and underscoring potential needs for preventive and therapeutic care where possible.

21 Jan 2021

PromoCell's New GMP Certification - EXCiPACT

In this interview, News-Medical talks to Dr. Irma Börcsök (CEO of PromoCell) and Dörte Keimer (Head of Quality Assurance) about PromoCell, the work they do and the latest GMP certification the company has achieved - EXCiPACT.

From PromoCell 21 Jan 2021

Monocytes could be a key player in sarcoidosis pathogenesis, study shows

The cause of the inflammatory lung disease sarcoidosis is unknown.

21 Jan 2021

T Cell News and Research

Latest T Cell News and Research

Modified version of CAR T-cell therapy shows promise in targeting neuroblastoma

Researchers develop comprehensive framework to classify small-cell lung cancer

New study helps understand molecular profile of tumors in cancer patients

Mitochondrial mutation linked to elevated diabetes risk in Japanese men

Pfizer-BioNTech vaccine shows reduced neutralization potential against SARS-CoV-2 B.1.1.7 spike variant

New drug target valid for breast cancer as well as lymphoma

SARS-CoV-2 suppresses host innate immunity

Researchers identify genetic risk factors contributing to pneumonia susceptibility and severity

Investigational combo therapy shows promise in treating TP53 mutant MDS and AML patients

FDA approves first injectable, complete regimen for HIV-1 infection in adults

Scientists identify a molecular mechanism that protects the fetus from maternal infection

AACR and MPM award three grants to support groundbreaking cancer research projects

SU2C announces $3.25 million in grants to find new treatments for head and neck cancers

A single genetic test can identify the presence and cause of mismatch repair deficiency

Researchers use SARS-CoV-2 to bioengineer universal vaccine platform

New sensory neuron model enables easy generation of cells to fast-track pain research

High factor V levels linked to lymphopenia and weakened immunity in severe COVID-19

Blood group associated with cardiovascular events in COVID-19 patients

PromoCell's New GMP Certification - EXCiPACT

Monocytes could be a key player in sarcoidosis pathogenesis, study shows

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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