Life Science Articles

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What are Telomeres?

Telomeres are crucial parts of the chromosome that act to protect them and ensure DNA replication is performed effectively.

21 May 2019

Hair Analysis in Forensic Science

Hair samples are one of the most important resources in the forensic analysis of crime scenes, often providing valuable information that can help to lead to the identification of a suspect or victim.

21 May 2019

Protein Crystallization Screening

High throughput crystallization techniques are frequently employed to generate the large numbers of high purity protein crystals needed for protein crystallography.

2 May 2019

What is Comparative Genomics?

This article aims to describe the techniques used in comparative genomics and their advantages/disadvantages.

22 May 2019

Transmission Raman Spectroscopy Advantages and Limitations

Transmission Raman Spectroscopy (TRS) is a useful technique for the bulk analysis of materials that are opaque or turbid, such as pharmaceutical tablets.

13 May 2019

Forensic Confirmation Bias (Cognitive Bias in Forensics)

Forensic confirmation bias describes how an individual’s personal motives can affect the way in which criminal evidence is collected and evaluated.

13 May 2019

cGAS–STING Pathway Steps, Regulation, and Oncogenesis

The cGAS–STING pathway is a part of the innate immune system and is involved in the detection of cytosolic deoxyribonucleic acid (DNA).

13 May 2019

T-Cell Metabolism, Immunodeficiency and Human Disease

T cells are a critical component of the human adaptive immune system and are indispensable in protecting host organism from pathogens.

13 May 2019

Raman Imaging Techniques

Raman imaging techniques are used to obtain information about the molecular vibrations and crystal structure of a sample.

9 May 2019

Mitochondrial DNA Organization and Replication Steps

This article describes the organization of mitochondrial DNA into nucleoids and the replication process, including initiation, elongation, termination and the involvement of polymerase enzymes.

9 May 2019

Raman Spectroscopy: Factors that Affect Spectral Resolution

There are several factors that can affect the spectral resolution of a Raman confocal microscope. This article describes each of these factors and how they can be overcome.

8 May 2019

CRISPR-Cas14: Discovery, Function, Advantages

CRISPR-Cas14 is a variation of the CRISPR-Cas gene editing system which benefits from being simpler and smaller than the other versions.

8 May 2019

Carbon Nanotubes (CNTs) for Targeted Antimicrobial Drug Delivery

Carbon nanotubes show a very good level of cell penetration compared to other drug delivery systems and are less toxic.

8 May 2019

Single-particle Cryo-EM Principles & Uses

Single-particle cryo-EM is an analytical technique used to deduce the 3D structure of macromolecules (particularly proteins) as an alternative to X-Ray crystallography.

2 May 2019

LC-MS for HCP Detection and Analysis

Liquid-chromatography mass spectrometry (LC-MS) is a potential method for detecting HCPs in biopharmaceutical products.

2 May 2019

Human Cell Line Authentication by STR Profiling

Short Tandem Repeat (STR) DNA profiling is one solution that has been proposed for the detection of cross-contamination and therefore authentication of human cell lines.

2 May 2019

Cell‐Cycle‐Dependent Regulation of Cell Adhesions

This article will describe recent studies which have expanded our knowledge of the role of focal adhesions in the cell cycle.

2 May 2019

Eukaryotic DNA Polymerase Enzymes

For all species, the process of DNA replication requires the use of multiple different DNA polymerase enzymes.

1 May 2019

History of DNA Research: Scientific Pioneers & Their Discoveries

This article aims to provide a brief overview of the history of DNA research, leading up to Watson and Crick's discovery of the structure of DNA, and what came next.

1 May 2019