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ELISA versus Mass Spectrometry for the Detection of HCPs

Studies show that mass spectrometry is more sensitive to low abundance HCPs, which may be missed by ELISAs.

8 Apr 2019

EC-MS Applications in Neuroscience

Electrochemical mass spectrometry (EC-MS) is a technique that is used to characterize and analyze the effects of redox reactions on biomolecules, such as proteins peptides and nucleic acids.

8 Apr 2019

Controlling the Cellular Microenvironment in vitro

Using cell cultures, scientists are able to manipulate the cellular microenvironment in order to simulate physiological conditions in vivo.

8 Apr 2019

Biomedical Applications of Isotope-Dilution Liquid Chromatography

Isotope dilution chromatography can be used to analyze sugar levels in alcohol and human disease, as well as the nutritional value of supplements and activated carboxylates in cells and tissues.

8 Apr 2019

Best Chromatographic Techniques for Pesticide Analysis

As consumers become progressively more aware of what is in their food, pesticide analysis is becoming increasingly important.

5 Apr 2019

Benefits of Multiplex Immunoassays

There are two main ways of multiplexing an immunoassay; spatial separation or immobilizing antibodies onto different beads based on what they target.

5 Apr 2019

Background Noise in Western Blots

The key to a successful Western blot is achieving a signal to noise ratio allowing the detection of proteins while minimizing the background noise.

5 Apr 2019

Applications of CLARITY

One potent application of CLARITY lies in its ability to allow clear imaging of the human brain during pathogenesis or diseased state.

5 Apr 2019

Applications of Carbon Nanotubes (CNTs) in Regenerative Medicine

Regenerative medicine refers to the use of technology to directly or indirectly regenerate or grow and replace cells, tissues, or organs. Recently, CNTs have been used to support bone and tissue regeneration.

5 Apr 2019

Structural Motifs in Protein Biology

This article describes each type of structural motif in secondary protein structures, with examples.

5 Apr 2019

Single-Nucleus RNA Sequencing (sNuc-seq) Protocol

This article describes the laboratory protocol for Single Nucleus RNA Sequencing (sNuc-seq).

5 Apr 2019

Single-Nucleus RNA Sequencing (sNuc-seq) Applications

In earlier studies investigating RNA or DNA, all the cells of a population were pooled together to collect information.

3 Apr 2019

Secondary Transfer of DNA in Forensics

Secondary DNA transfer occurs when DNA is transferred to an object or person through an intermediate.

3 Apr 2019

What is Single-Particle Cryo-Electron Microscopy?

Single particle cryo-EM helps to determine the three-dimensional structure of molecules and assemblies without crystallizing the samples.

3 Apr 2019

What is the Cellular Microenvironment?

The cellular microenvironment is defined as the local environment surrounding a cell, which contains physical and chemical signals that can influence cellular behavior.

3 Apr 2019

What are Adipocytes?

With obesity rates rising worldwide, there is a growing interest in understanding the formation and regulation of fat cells, or adipocytes, and how an increase in their number leads to disease.

1 Apr 2019

Using Small-Angle X-Ray Scattering (SAXS) to Study Metabolism

Small-Angle X-Ray Scattering (SAXS) is gaining importance in the field of metabolomics, for the assessment of metabolic state and related disorders.

1 Apr 2019

Using EC-MS to Study Neurotransmission

Apart from being used to understand the mechanism of various redox reactions, EC-MS can also be used to study the electrochemical changes involved in neurotransmission.

1 Apr 2019

Reflection Contrast Microscopy for Immunocytochemistry

As reflection contrast microscopy can generate high definition images at high penetration depths, it is commonly used in immunocytochemistry.

1 Apr 2019

Ribosome Structure

Ribosomes are highly complex, macromolecular structures that fulfil the vital role of protein synthesis in all living cells across species, from bacteria to eukaryotes.

3 Apr 2019