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Camelid Antibodies – Advantages and Limitations

Camelid antibodies (or VHHs) are small, stable nanobodies that permeate the blood-brain-barrier easily. However, they are rapidly cleared from the body.

25 Jan 2019

How are Host Cell Proteins Removed from Biopharmaceuticals?

Removing host cell proteins is crucial, as these proteins are immunogenic and can thus compromise the integrity of the final product.

25 Jan 2019

GC-MS Analysis of CBD and THC

Components of cannabis include tetrahydrocannabinol (THC), cannabidiol (CBD), and cannabinol (CBN). One method by which cannabis is analyzed is through GC-MS.

25 Jan 2019

What is Antibody Feeding?

Antibody feeding is a method used to visualize receptor endocytosis and trafficking of neurotransmitter receptors.

25 Jan 2019

Biofilm Analysis: Tools and Techniques

Biofilms are found in many different settings, providing advantages in industry and disadvantages in human health. As these structures are so complex and found in many different environments, there are lots of different tools and techniques used to monitor and analyze them.

23 Jan 2019

What are Camelid Antibodies?

Camelid single-domain antibodies (also known as nanobodies or VHHs) are derived from the Camelidae family of mammals such the llamas, camels, and alpacas. Unlike other antibodies, camelid antibodies lack a light chain and are composed of two identical heavy chains.

23 Jan 2019

How to Write a Scientific Abstract

The abstract of a scientific paper must concisely convey the background, purpose, methodology and conclusions of the published work. This section is visible to the readers even in cases where access to full articles is not available, and is usually published in conference proceedings to outline the content of a talk or seminar.

22 Jan 2019

Antigen Retrieval: Methods, Tips and Techniques

Antigen retrieval techniques are used to enhance signals in immunohistochemical testing.

22 Jan 2019

Potential Contaminants in CBD and THC Oils

Cannabidiol (CBD) was initially discovered as a medication to treat Dravet syndrome, but is now used extensively to treat several medical and lifestyle disorders in addition to being used as recreational drug.

22 Jan 2019

What is Small-Angle X-Ray Scattering (SAXS)?

Small-angle X-ray scattering (SAXS) is an analytical technique to determine differences in density within a sample with a nanoscale resolution by analyzing the elastic scattering angles of X-rays.

22 Jan 2019

What is Parallel Accumulation and Serial Fragmentation (PASEF)?

PASEF is a spectroscopic technique used during LC-MS based proteomics to improve sequencing speed and sensitivity.

24 Jan 2019

What is Nutritional Genomics (Nutrigenomics)?

This article describes the applications of nutritional genomics, which involves the study of nutrition and its relationship with the genome.

24 Jan 2019

Temperate Bacteriophages and the Lysogenic Cycle

Temperate bacteriophages display a lysogenic life cycle, which requires them to integrate their viral genome into the bacterial chromosome.

24 Jan 2019

Techniques Used in Targeted Metabolomic Profiling

Targeted metabolomics refers to the presence and concentration of specific metabolites associated with a particular disease.

24 Jan 2019

Pyroptosis Pathway and Triggers

Pyroptosis is an inflammatory form of programmed cell death that occurs during microbial infections.

24 Jan 2019

NMR-Based Metabolomics

Nuclear magnetic resonance (NMR) spectroscopy is commonly used to identify and quantify metabolites in a sample.

24 Jan 2019

Metabolomic Profiling for Disease Diagnosis

Understanding the metabolic changes that occur in various disease states allows a more accurate diagnosis to be made.

22 Jan 2019

Virulent Bacteriophages and the Lytic Cycle

Lytic bacteriophage hijack the molecular machinery of a bacterial cell to make lots of progeny, and then burst, or lyse, the host cell.

22 Jan 2019

Uses of Short Hairpin RNA (shRNA) Interference

RNA interference refers to effective silencing or knocking down of a target gene by degrading its corresponding mRNA using short hairpin RNA (shRNA).

22 Jan 2019

Sequencing Antibodies

The investigation into the genetic makeup of antibodies is essential for antibody engineering, database banking, and the discovery of novel antibody clones.

22 Jan 2019