Life Science Articles

RSS

Exosome Analysis Using Flow Cytometry

Flow cytometry can be used to detect and characterize exosomes based on their cell surface markers.

12 Dec 2018

Stem Cell Niches: Lessons Learned from Drosophila

The Drosophila ovary is a model system used to investigate the functional interactions between stem cells and their niches (microenvironments that maintain stemness).

11 Dec 2018

What is Organ-on-a-Chip (OOC)?

Organ-on-a-chip technology combines engineered three-dimensional tissue within a microfluidic system to simulate the mechanics and physiology of entire organs.

11 Dec 2018

How are Antibodies Conjugated?

A wide variety of molecules can be conjugated to antibodies, and their selection is dependent on their intended use: clinical or non-clinical.

11 Dec 2018

History of Stem Cells

Stem cell discovery began in the 1950s with teratocarcinomas and tumor heterogeneity. The latest discovery was iPS cells in 2006.

11 Dec 2018

ELISA Applications

ELISA is a biomolecular technique that can be used to detect and quantify molecules such as hormones, peptides, antibodies, and proteins.

6 Dec 2018

De Novo Protein Structure Prediction

De novo protein structure prediction uses algorithms to determine the tertiary structure of a protein based on its primary sequence.

6 Dec 2018

Bioorthogonal Chemistry in Research

The phrase ‘bioorthogonal’ was coined in 2003, and bioorthogonal chemistry is now widely used in research to study biomolecules in living systems.

6 Dec 2018

Cancer Stem Cell (CSC) Hypothesis

This article describes the cancer stem cell (CSC) hypothesis; the theory that a tumor contains a small population of stem cells that drive metastasis.

6 Dec 2018

Gold Nanoparticles in Photoacoustic Tomography

This article describes photoacoustic tomography and the use of gold nanoparticles as a contrast agent.

3 Dec 2018

Clathrin-mediated Endocytosis

In clathrin-mediated endocytosis, the cell membrane invaginates to take up metabolites, hormones, and proteins from the cell surface into intracellular vesicles.

3 Dec 2018

Using Fluorescence Microscopy to Study Proteins

Fluorescence microscopy can be used visualize proteins inside live cells. This is particularly useful when studying signaling pathways and binding partners.

28 Nov 2018

What are Fluorescent Proteins?

After the discovery of green fluorescent protein (GFP) in 1961, fluorescent proteins have been fused to various proteins and enzymes in order to visualize them.

28 Nov 2018

mRNA Display: Applications in Research

mRNA display is a technique that can identify proteins which bind to specific regions in DNA. This method has several advantages over other methods, such as yeast-to-hybrid, immunoprecipitation, phage display and others.

27 Nov 2018