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Clinical patient safety interventions reduce errors in obstetrical care

Researchers at Yale School of Medicine have implemented patient safety enhancements to dramatically reduce errors and improve the staff's own perception of the safety climate in obstetrical care.

5 Feb 2008

iPods shown not to interfere with pacemakers

A report in the open access journal BioMedical Engineering OnLine refutes claims that portable music players, such as Apple's iPod, interfere with cardiac pacemakers.

5 Feb 2008

Experimental biomarker test beats PSA in detecting prostate cancer

An experimental biomarker test developed by researchers at the University of Michigan more accurately detects prostate cancer than any other screening method currently in use, according to a study published in the February 1 issue of Cancer Research, a journal of the American Association for Cancer Research.

5 Feb 2008

Enbrel shown to significantly reduced levels of C-reactive protein

Amgen and Wyeth Pharmaceuticals, a division of Wyeth have announced findings from a retrospective analysis, which demonstrated that ENBREL reduced C-reactive protein (CRP), a marker of inflammation, in patients with moderate to severe plaque psoriasis following 12 weeks of treatment. Median reduction in CRP levels was 10 times greater in the ENBREL treated group compared to the placebo treated group.

5 Feb 2008

New vaccine for malaria under trial

Trials are underway, funded by the Wellcome Trust, for a new vaccine to combat the most deadly form of malaria.

5 Feb 2008

Larynx preservation preferred over total laryngectomy

Patients with locally advanced laryngopharyngeal cancers who receive radical chemoradiation have significantly better voice outcomes during the 12 months following treatment when compared with patients who have undergone a total laryngectomy and surgical voice restoration, according to a study in the February 1 issue of the International Journal for Radiation Oncology-Biology-Physics, the official journal of the American Society for Therapeutic Radiology and Oncology.

5 Feb 2008

Precise geometry and energy of protein structures holds key to cures

Your mother always told you to do your geometry homework, and for scientists seeking new treatments for diseases like Parkinson's and Alzheimer's, this advice turns out to be right on the mark.

5 Feb 2008

The obesity epidemic - does the evidence stack up?

Last week, the UK health secretary declared that we are in a grip of an obesity epidemic, but does the evidence stack up? Researchers in this week's BMJ debate the issue.

5 Feb 2008

Chemists track how amantadine drug changes, blocks flu virus

An anti-virus drug attacks influenza A by changing the motion and structure of a proton channel necessary for the virus to infect healthy cells, according to a recently published research paper by two Iowa State University chemists.

5 Feb 2008

Genetic mutations in the Toll-like receptor 4 gene increase risk of preterm birth

Genetic mutations in the Toll-like receptor 4 (TLR4) gene appear to have significant association with inflammatory injury to the placenta and developing baby, researchers from the University of Pittsburgh's department of obstetrics, gynecology and reproductive sciences report at the 28th annual meeting of the Society for Maternal-Fetal Medicine.

5 Feb 2008

Gene ENPP1 is linked to preterm birth and low birth weight among Hispanic women

Researchers at Yale School of Medicine have found that the gene ENPP1 is linked to preterm birth and low birth weight among Hispanic women.

5 Feb 2008

Gene in grain-producing plants guards against infection in animals and humans

Purdue University and USDA-Agricultural Research Service scientists have discovered that a type of gene in grain-producing plants halts infection by a disease-causing fungus that can destroy crops vital for human food supplies.

5 Feb 2008

New FDA advisory on Chantix (varenicline)

The U.S. Food and Drug Administration (FDA) has issued a Public Health Advisory to alert health care providers, patients, and caregivers to new safety warnings concerning Chantix (varenicline), a prescription medication used to help patients stop smoking.

5 Feb 2008

FDA approves Endeavor Zotarolimus-eluting coronary stent

The U.S. Food and Drug Administration has approved the Endeavor Zotarolimus-Eluting Coronary Stent for use in treating patients with narrowed coronary arteries, the blood vessels supplying the heart.

5 Feb 2008

Antiepileptic drug warning from FDA

The U.S. Food and Drug Administration today issued new information to health care professionals to alert them about an increased risk of suicidal thoughts and behaviors (suicidality) in patients who take drugs called antiepileptics to treat epilepsy, bipolar disorder, migraine headaches, and other conditions.

5 Feb 2008

Eye blinks may help to identify children prenatally exposed to alcohol

While children with fetal alcohol syndrome (FAS) have identifiable craniofacial abnormalities, children with alcohol-related neurodevelopmental disorder (ARND) can have significant cognitive impairments without facial anomalies. An important new study has found that a deficit in eyeblink conditioning (EBC) can identify children with probable FAS, and may also serve to identify alcohol-exposed children who lack distinctive FAS features.

5 Feb 2008

European regulatory agencies should employ full-time statisticians

European regulatory agencies should employ full time statisticians to enable competent licensing and labelling decisions to be made, argue leading statisticians in an open letter to this week's BMJ.

5 Feb 2008

U.S. efforts to eliminate tuberculosis fall short

The U.S. is likely to fall far short of its benchmark goals toward eliminating tuberculosis as a public health problem, according to data from a nationwide survey.

5 Feb 2008

Early detection of pediatric thyroid cancer critical

Efforts to treat pediatric papillary thyroid cancer are greatly improved by detecting the disease as early as possible, making the patient's age the most important factor in determining a prognosis, according to new research published in the February 2008 issue of the journal Otolaryngology Head and Neck Surgery.

5 Feb 2008

Novel drug romiplostim significantly improves treatment of dangerous blood disorder

Two clinical trials of the novel drug romiplostim (Nplate) show that it significantly improved platelet levels in patients with chronic immune thrombocytopenic purpura (ITP), a hematologic disorder that can cause uncontrolled bleeding.

5 Feb 2008