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First patient enrolled in phase III study of Bevacizumab and Trastuzumab in early breast cancer

A new international study for women with HER2-positive breast cancer is open for enrollment. The pivotal BETH (BEvacizumab and Trastuzumab Adjuvant Therapy in HER2-positive Breast Cancer) study is a Phase III clinical research trial that is investigating the benefits of combining two monoclonal antibodies, the anti-angiogenic, bevacizumab (Avastin) and the targeted therapy trastuzumab (Herceptin), together with chemotherapy for the treatment of patients with early stage HER2-positive breast cancer.

27 May 2008

Barr confirms Entocort patent challenge

Barr Pharmaceuticals, Inc. today confirmed that its subsidiary, Barr Laboratories, Inc., has initiated a challenge of the patents listed by AstraZeneca LP in connection with its Entocort(R) Enteric Coated Capsules (budesonide), 3mg.

27 May 2008

Patients to benefit from multi-million pound research funding

NHS patients in North West London will benefit from a multi-million pound research project leading to the rapid introduction of new, effective treatments for a wide range of medical conditions.

27 May 2008

Digital Healthcare appointed to major NHS Framework contract

NHS Connecting for Health, on behalf of the NHS, has appointed Digital Healthcare to the NHS Additional Supply Capability & Capacity (ASCC) Framework following open competition bids to provide additional capacity and capability in the supply of IT products and services to the NHS.

27 May 2008

Nurse-midwives present blankets for babies to Boston area women's organizations

Women, newborns, and families in the Boston area will benefit from the contributions of new and handmade blankets during the American College of Nurse-Midwives (ACNM) annual Blankets for Babies public service campaign during the ACNM 53rd Annual Meeting & Exhibit in Boston. Three area women's organizations will receive baby blankets, which are donated by certified nurse-midwives, certified midwives, student nurse-midwives, exhibitors and other meeting guests.

27 May 2008

Avoiding spleen removal for Cooley's anemia sufferers

Researchers from Weill Cornell Medical College may have discovered the precise role of a gene in one of the world's most common blood disorders, beta-thalassemia, commonly known as Cooley's anemia. Along with sickle-cell anemia, Cooley's anemia is the most commonly inherited disease in the world, affecting many people of Mediterranean descent, and 20 out of every 100,000 African-Americans. The World Health Organization estimates that between 50,000-100,000 children are born with the disease each year.

27 May 2008

Exercise cuts cancer deaths in men

Men who exercise often are less likely to die from cancer than those who don't, new research published in the British Journal of Cancer reveals today.

27 May 2008

Molecular fingerprint of cocaine addiction revealed

The first large-scale analysis of proteins in the brains of monkeys addicted to cocaine reveals new information on how long-term cocaine use changes the amount and activity of various proteins affecting brain function.

27 May 2008

RNA toxicity contributes to neurodegenerative disease

Expanding on prior research performed at the University of Pennsylvania, Penn biologists have determined that faulty RNA, the blueprint that creates mutated, toxic proteins, contributes to a family of neurodegenerative disorders in humans.

27 May 2008

Increased screening may better predict those at higher risk for heart disease

Adding noninvasive imaging to current risk-assessment protocols may identify more people who are at risk of developing heart disease, UT Southwestern Medical Center researchers have found.

27 May 2008

Gum disease an indicator of increased cancer risk

British scientists say gum disease, both in smokers and non-smokers, may be a warning sign of an increased risk of cancer.

27 May 2008

Antipsychotic drugs dangerous for the elderly

A Canadian study has found that prescribing antipsychotic drugs for elderly people may be dangerous.

27 May 2008

New generation of insect repellents in the pipeline

The next generation of insect repellents could be in the pipeline with research from the U.S. suggesting seven possibilities.

27 May 2008

Warning about the danger of yet another bird flu virus

Scientists in the United States have identified a second H strain of bird flu that could cause a pandemic, they say the H5N1 strain of bird flu currently circulating the globe is not the only cause for concern.

27 May 2008

Thousands with type 2 diabetes at risk bacause they do not take their drugs

According to Diabetes UK, in excess of 650,000 people with obesity-related diabetes do not take their drugs and the charity says they are putting themselves at risk of developing serious health problems such as stroke and blindness.

27 May 2008

Methadone to be dumped in Scotland as treatment for heroin addiction

A new approach to tackling heroin addiction is about to be tried out in the United Kingdom.

27 May 2008

Breakthrough by WHO will give poor countries better access to drugs

An agreement has been reached by world health leaders regarding approaches to drug research and development and improving access to medicines.

27 May 2008

Blood cholesterol levels predict risk of heart disease due to hormone therapy

A new analysis of a subgroup of participants in the Women's Health Initiative (WHI) hormone therapy clinical trials suggests that healthy, postmenopausal women whose blood cholesterol levels are normal or lower are not at increased, short-term risk for heart attack when taking hormone therapy.

26 May 2008

New cheaper method for mapping disease genes

Scientists at the Swedish medical university Karolinska Institutet have developed a new DNA-sequencing method that is much cheaper than those currently in use in laboratories. They hope that this new method will make it possible to map disease genes in large patient groups, which in turn can mean quicker breakthroughs for new treatments for a wide variety of diseases.

26 May 2008

New treatments for viral and other diseases by blocking genes

The elusive goal of developing effective treatments for viral diseases such as AIDS and influenza has been brought closer by dramatic progress in the ability to interfere with viral genetic machinery. The stage was set for a coordinated European effort to accelerate research and stimulate development of new treatments against viral diseases at a recent research conference organised by the European Science Foundation (ESF).

26 May 2008