What if you could map the chemistry inside a human cell - without fluorescent labels or stains?

Cells are chemically crowded, spatially complex and notoriously difficult to interpret using conventional infrared microscopy alone. Professor Kamilla Malek and her colleagues are developing a clearer view by combining FTIR spectroscopy, submicron O-PTIR microscopy, Raman imaging and advanced chemometrics to transform overlapping vibrational spectra into meaningful maps of cellular composition.
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Drawing on the team’s recent Analytical Chemistry publication, “"IR Map of the Human Cell"”, and its broader research across 2D and 3D cellular models, Professor Malek will demonstrate how label-free vibrational imaging can distinguish nuclei, cytoplasm, lipid-rich and glycogen-rich regions - and reveal biochemical changes associated with differentiation, metabolism, disease and cell-cell interactions.
What you will learn
- How FTIR, submicron O-PTIR and Raman imaging provide complementary views of cellular chemistry
- How spectral “barcodes” differentiate nuclei, cytoplasm and lipid- or glycogen-rich cellular regions
- How chemometrics and biomolecular reference modelling help unravel heavily overlapping biological spectra
- How these approaches can phenotype bladder-cancer cells, monitor stem-cell differentiation and investigate neuronal spheroids and blood-brain-barrier models
- What changes when vibrational imaging moves from isolated cells to complex 2D and 3D biological systems
Who should attend?
This webinar will be particularly valuable for researchers working in:
- FTIR, O-PTIR and Raman microscopy
- Single-cell and subcellular chemical imaging
- Cell biology, cancer research and regenerative medicine
- Neuroscience and blood-brain-barrier research
- 2D and 3D in vitro models
- Chemometrics and label-free biological analysis
Register now to discover how label-free molecular imaging can turn complex spectra into biological insight–from chemical detail inside a single cell to phenotyping sophisticated 3D models.
Can’t attend live? Register anyway to receive access to the recording.
See you there on Thursday, September 17, 2026
Guest speaker
Professor Kamilla Malek, Jagiellonian University
Host
Dr. Mustafa Kansiz, Photothermal Spectroscopy Corp
Register now