1. 5 fold risk increase mis-leading
    Andrew Andrew Japan says:
    December 15, 2009 at 1:27 PM

    "Low HDL-C and/or elevated triglycerides (TG) was seen in nearly two- thirds of MI patients,"

    The comparative figure for the control group should also be given.

    In addition I question the findings of the "5 fold increase risk" figure.

    Surely, in the control group it would be difficult to find many people with such an excellent LDL-C profile (less than or equal to 100mg/dL) and concurrent low HDL-C and high TG. There would be more men in the MI group who match this profile as they would likely have been treated with LDL lowering statins, thus confounding the figures.

    More detail as to how you reached the remarkably high "5 fold increase risk" would be appreciated.

    I don't doubt low HDL-C & high TG are independant risk factors for CHD, but the "5 fold" figure must apply only to a very small subset of patients, and certainly not to men in general.

    Reply
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