Antibodies News and Research

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Omicron subvariants BA.2.12.1, BA.4, and BA.5 show higher neutralization resistance to antibodies

In a recent study published in The Lancet Infectious Diseases, researchers investigated the neutralization sensitivity of the emerging Omicron sub-variants, BA.2.12.1, BA.4, and BA.5.

30 Jun 2022

Novel universal flu vaccine confers protection against different strains and subtypes of influenza A viruses

A new universal flu vaccine constructed with key parts of the influenza virus offers broad cross protection against different strains and subtypes of influenza A viruses in young and aged populations, according to a new study by researchers in the Institute for Biomedical Sciences at Georgia State University.

30 Jun 2022

Rapid test can identify which variant has infected a COVID-19 patient in just a few hours

In just a few hours, UT Southwestern scientists can tell which variant has infected a COVID-19 patient – a critical task that can potentially influence treatment decisions but takes days or weeks at most medical centers.

30 Jun 2022

South African study shows COVID severity of Omicron BA.1, BA.4, BA.5 all similar

A recent article posted to the medRxiv* preprint server analyzed the illness severity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.4/BA.5 and prior viral waves in the Western Cape, South Africa.

30 Jun 2022

How to develop an "all-variant" COVID vaccine

In a recent study published in Nature Immunology, researchers summarized their observations of humoral immune responses elicited in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infected people. Additionally, they discussed all the types of SARS-CoV-2 infection- and vaccine-induced neutralizing antibodies (nAbs).

30 Jun 2022

Casirivimab/imdevimab improve outcomes in early COVID-19

A new Viruses study determines the effect of casirivimab/imdevimab on IFN-1 and cytokines during SARS-CoV-2 infection.

29 Jun 2022

SARS-CoV-2 3CLpro also susceptible to mutations

Researchers assess the activity of all potential mutations in the SARS-CoV-2 3CLpro.

29 Jun 2022

Scientists report autoimmunity from molecular mimicry between SARS-CoV-2 spike and human proteins

A new study focused on studying molecular mimicry between the S protein of SARS-CoV-2 and known epitopes, using a computational method.

29 Jun 2022

COVID-19 pandemic linked to lower antibodies in breastmilk

New research describes the results of a study measuring such protection and exploring the effects of waning antibody levels on infant susceptibility to respiratory pathogens.

29 Jun 2022

Researchers explore disease severity post-infection with SARS-CoV-2 Omicron in hematologic patients

A new study has studied the clinical outcome and spectrum in 61 patients infected with the SARS-CoV-2 Omicron variant.

29 Jun 2022

Epigenome-wide DNA methylation patterns in convalescent COVID-19 subjects

Researchers investigated the epigenetic rewiring of odor perception in SARS-CoV-2-infected cells.

29 Jun 2022

Study finds Omicron variant could break through vaccine protection more effectively than the Delta variant

Researchers assessed the efficacy of vaccinations against SARS-CoV-2 Delta and Omicron variants of concern.

29 Jun 2022

Immune particles from llama blood could offer protection against several COVID-19 variants

Mount Sinai-led researchers have shown that tiny, robust immune particles derived from the blood of a llama could provide strong protection against every COVID-19 variant, including Omicron, and 18 similar viruses including SARS-CoV-2 and SARS-CoV-1, which was responsible for the 2003 SARS outbreak.

29 Jun 2022

Memory B cells can be localized in the lungs, research shows

How can we increase the efficacy of vaccines used to protect against viral respiratory diseases such as influenza and COVID-19? Scientists from Inserm, CNRS and Aix-Marseille Université at the Center of Immunology Marseille-Luminy are opening up new prospects in the field, with the triggering of memory B cells directly in the lungs looking to be a promising avenue.

28 Jun 2022

Study explores antibody responses following three COVID vaccine doses in kidney transplant recipients

In a recent study posted to the medRxiv* pre-print server, Canadian researchers evaluated antibody responses in kidney transplant recipients (KTRs) before and one and three months after receiving the third dose of a messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine.

28 Jun 2022

Study compares protection induced by Delta breakthrough infections vs. COVID boosters against Omicron

Researchers compare the neutralizing ability of antibodies induced by Delta breakthrough infections and a third COVID-19 vaccine against Omicron.

28 Jun 2022

BNT162b2 COVID vaccine stimulates significant antibody response in lung cancer patients

In a recent article posted to the medRxiv* preprint server, scientists from Japan assessed the safety and immunogenicity of coronavirus disease 2019 (COVID-19) BNT162b2 vaccine among lung cancer patients under treatment.

28 Jun 2022

Acute COVID-19 and vaccination induce cross-reactive antibody responses in breast milk

IgA and IgG in human breast milk and blood were assessed for their activity against SARS-CoV-2 and SARS-CoV-1, as well as four other prevalent HCoVs.

28 Jun 2022

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States described a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibody (mAb) SP1-77 that broadly neutralized its multiple variants of concern (VOCs).

28 Jun 2022

Low rates of severe COVID-19 found in patients treated with monoclonal antibodies during delta surge

A study of 10,775 high-risk adult patients during the COVID-19 delta variant surge in late 2021 finds that treatment with one of three anti-spike neutralizing monoclonal antibodies for mild to moderate symptoms led to low rates of severe disease, hospitalization, ICU admission and mortality, according to Mayo Clinic researchers.

28 Jun 2022

Antibodies News and Research

Omicron subvariants BA.2.12.1, BA.4, and BA.5 show higher neutralization resistance to antibodies

Novel universal flu vaccine confers protection against different strains and subtypes of influenza A viruses

Rapid test can identify which variant has infected a COVID-19 patient in just a few hours

South African study shows COVID severity of Omicron BA.1, BA.4, BA.5 all similar

How to develop an "all-variant" COVID vaccine

Casirivimab/imdevimab improve outcomes in early COVID-19

SARS-CoV-2 3CLpro also susceptible to mutations

Scientists report autoimmunity from molecular mimicry between SARS-CoV-2 spike and human proteins

COVID-19 pandemic linked to lower antibodies in breastmilk

Researchers explore disease severity post-infection with SARS-CoV-2 Omicron in hematologic patients

Epigenome-wide DNA methylation patterns in convalescent COVID-19 subjects

Study finds Omicron variant could break through vaccine protection more effectively than the Delta variant

Immune particles from llama blood could offer protection against several COVID-19 variants

Memory B cells can be localized in the lungs, research shows

Study explores antibody responses following three COVID vaccine doses in kidney transplant recipients

Study compares protection induced by Delta breakthrough infections vs. COVID boosters against Omicron

BNT162b2 COVID vaccine stimulates significant antibody response in lung cancer patients

Acute COVID-19 and vaccination induce cross-reactive antibody responses in breast milk

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

Low rates of severe COVID-19 found in patients treated with monoclonal antibodies during delta surge

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