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Effectiveness of monoclonal antibodies and directly acting antivirals against SARS-CoV-2 Omicron BA.1 and BA.2 sublineages

Researchers assessed the in vivo effectiveness of monoclonal antibodies and directly acting antiviral agents against the SARS-CoV-2 Omicron BA.1 and BA.2 sublineages.

28 Jun 2022

The potential of DNA-based SARS-CoV-2 vaccine candidates

Researchers evaluated the immunogenicity of DNA-based candidate vaccines against SARS-CoV-2 in mice.

28 Jun 2022

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

A recent study by scientists at Celentyx Ltd, the University of Birmingham, and the University of Warwick and posted to the bioRxiv* preprint server illustrated a cell-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein attachment assay.

28 Jun 2022

A cancer patient who had SARS-CoV-2 for over eight months

In a recent study posted to the medRxiv* pre-print server, researchers in Israel described the case of a severely immunocompromised cancer patient who developed a chronic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

28 Jun 2022

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

In a recent article posted to the bioRxiv* preprint server, researchers at Texas Biomedical Research Institute, Georgia State University, and the University of Alabama at Birmingham developed a bireporter-expressing recombinant severe acute respiratory syndrome coronavirus 2 (rSARS-CoV-2) for tracking SARS-CoV-2 infection.

27 Jun 2022

Breakthrough infection with pre-Omicron variant induces cross-neutralizing activity against Omicron

Researchers evaluated the neutralizing ability of sera from COVID-19 patients.

27 Jun 2022

Review and case study illustrates the challenges of monkeypox

A new paper published in Travel Medicine and Infectious Disease reviews the history of this disease in and outside Africa, with special reference to its clinical difficulties.

27 Jun 2022

Investigating PREVENT-19 trial findings of serological correlates of immune protection and risk against COVID-19

Researchers presented the PREVENT-19 phase 3 trial findings on the effectiveness of the NVX-CoV2373 adjuvanted, recombinant S nanoparticle vaccine.

27 Jun 2022

A full model of the SARS-CoV-2 spike protein for studying its atomic-level dynamics by multiple microsecond simulations

Researchers constructed a full-length SARS-CoV-2 spike structure in its membrane-bound state to study functionally relevant aspects of its global conformational dynamics.

27 Jun 2022

Study investigates the virological attributes of Omicron in a Syrian hamster model

Researchers investigated the virological attributes of SARS‐CoV‐2 new variant of concern Omicron in a Syrian hamster model.

27 Jun 2022

Antibody profiles of internal viral proteins predict severe COVID-19 outcomes

Most research on immunity to the SARS-CoV-2 virus and COVID-19 vaccine development has focused on antibody responses to the spike protein and other viral surface proteins.

24 Jun 2022

Serologic testing captures missed children at risk for long Covid

A new study provides evidence of the utility of serologic testing in helping to pick up children with long Covid following missed diagnoses of COVID-19.

24 Jun 2022

Natural and hybrid immunity dynamics in South African mothers

Researchers evaluated natural and hybrid immunity after four COVID-19 waves in South Africa.

24 Jun 2022

Associations between maternal COVID-19 vaccination and hospitalization among infants

Researchers assessed the efficacy of maternal mRNA vaccinations during pregnancy against hospitalization for COVID-19 in infants aged <6 months.

24 Jun 2022

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

A recent article posted to the bioRxiv* preprint server identified numerous efficacious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies from convalescent SARS-CoV-2 patients.

23 Jun 2022

Researchers continue a national study to evaluate COVID-19 vaccination safety pre-and post-delivery

With the SARS-CoV-2 pandemic ongoing, researchers at University of California San Diego School of Medicine, in collaboration with the American Academy of Allergy Asthma and Immunology, will continue a national study to evaluate the safety of COVID-19 vaccinations during pregnancy, and monitor immune response for mother and baby following vaccinations.

23 Jun 2022

The effect of immunization with bivalent oral poliovirus vaccine on the incidence of COVID-19

Researchers evaluated the impact of the OPV on the incidence of COVID-19.

23 Jun 2022

Correlates of anamnestic humoral immunity throughout SARS-CoV-2 variants of concern

A recent work posted to the bioRxiv* preprint server assessed the indicators of anamnestic humoral immunity among the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs).

23 Jun 2022

Research assesses ability of SARS‐CoV‐2‐neutralising mAbs to prevent COVID‐19

In a recent study published in the Cochrane Library, researchers searched multiple databases to identify randomized controlled trials (RCTs) that evaluated severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐neutralizing monoclonal antibodies (mAbs).

23 Jun 2022

Analyzing biophysical restrictions of SARS-CoV-2 N-terminal domain

In a recent article posted to the bioRxiv* preprint server, researchers at the University of Illinois at Urbana-Champaign, Scripps Research Institute, and Case Western Reserve University evaluated the biophysical limitations of the spike (S) N-terminal domain (NTD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

23 Jun 2022

Antibodies News and Research

Effectiveness of monoclonal antibodies and directly acting antivirals against SARS-CoV-2 Omicron BA.1 and BA.2 sublineages

The potential of DNA-based SARS-CoV-2 vaccine candidates

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

A cancer patient who had SARS-CoV-2 for over eight months

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

Breakthrough infection with pre-Omicron variant induces cross-neutralizing activity against Omicron

Review and case study illustrates the challenges of monkeypox

Investigating PREVENT-19 trial findings of serological correlates of immune protection and risk against COVID-19

A full model of the SARS-CoV-2 spike protein for studying its atomic-level dynamics by multiple microsecond simulations

Study investigates the virological attributes of Omicron in a Syrian hamster model

Antibody profiles of internal viral proteins predict severe COVID-19 outcomes

Serologic testing captures missed children at risk for long Covid

Natural and hybrid immunity dynamics in South African mothers

Associations between maternal COVID-19 vaccination and hospitalization among infants

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

Researchers continue a national study to evaluate COVID-19 vaccination safety pre-and post-delivery

The effect of immunization with bivalent oral poliovirus vaccine on the incidence of COVID-19

Correlates of anamnestic humoral immunity throughout SARS-CoV-2 variants of concern

Research assesses ability of SARS‐CoV‐2‐neutralising mAbs to prevent COVID‐19

Analyzing biophysical restrictions of SARS-CoV-2 N-terminal domain

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