immunity News and Research

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Global efforts to track COVID-19 variants grossly underreported a probable variant of concern in Nigeria

If the United States ignores COVID-19 in Nigeria, we forgo global genomic surveillance at our own peril, reports a new Northwestern Medicine study published in Nature Communications.

3 Feb 2022

CRISPRa method helps discover genes that play a role in immune cell biology

CRISPR genome editing has served as a powerful tool for deleting or altering DNA sequences and studying the resulting effect.

3 Feb 2022

Innate and adaptive immune responses to SARS-CoV-2 in convalescent children and adults

In a new study, researchers explored the systemic immune responses during the acute and convalescent phases of SARS-CoV-2 in children and adults with the same disease severity.

3 Feb 2022

Study describes the first three days of SARS-CoV-2 infection in an ALI model of proximal airway epithelium

Researchers evaluated the initial three days of SARS-CoV-2 infection via scRNAseq dataset in humanized in vitro model.

3 Feb 2022

A relative COVID-19 survival analysis

Researchers from the University of California Riverside, Texas A & M University, Washington University, and the Medical College of Georgia have been investigating the risks of death by age due to COVID-19 infection compared to deaths by other causes in Hubei province, China.

3 Feb 2022

Study results strongly support COVID mRNA vaccine boosters for nursing home residents

Researchers evaluate the vaccine effectiveness of mRNA booster dose in nursing home residents who completed the primary series of mRNA vaccination.

2 Feb 2022

Antigenic map of SARS-CoV-2 variants reveals amino acid substitutions that govern immune escape and immunodominance

Researchers use antigenic cartography to analyze cross-reactivity patterns of eight groups of human sera on a panel of SARS-CoV-2 variants.

2 Feb 2022

Omicron variant's 'milder' outcomes may be due to more population immunity

The SARS-CoV-2 Omicron variant's "milder" outcomes are likely due to more population immunity compared to earlier waves of the pandemic rather than the virus's properties, according to a paper by William Hanage, associate professor of epidemiology and co-director of the Center for Communicable Disease Dynamics at Harvard T.H. Chan School of Public Health, and Roby Bhattacharyya, assistant professor at Massachusetts General Hospital and Harvard Medical School and associate member at the Broad Institute of MIT and Harvard.

2 Feb 2022

Booster dose of Covaxin vaccine candidate neutralizes Omicron and Delta variants

Researchers evaluate the neutralization potential of sera samples from subjects boosted with the Covaxin against the SARS-CoV-2 Omicron variant.

2 Feb 2022

New evidence that positive framing could improve COVID vaccine uptake globally

Researchers applied message framing techniques to the side effects associated with the AstraZeneca, Pfizer, and Moderna COVID-19 vaccines.

2 Feb 2022

UK's world-leading human challenge study provides new insights into mild SARS-CoV-2 infections

Findings from the UK's world-leading human challenge study provide new insights into mild infections with SARS-CoV-2 in healthy young adults.

2 Feb 2022

Study discovers how long-term memory T cells are formed after SARS-CoV-2 exposure

Exposure to SARS-CoV-2 by infection or vaccination generates immune cells that provide long-term immunity. These long-lived memory T cells play a key role in preventing severe cases of Covid-19. Researchers at the University of Zurich have now discovered how these memory T cells form.

2 Feb 2022

The ability of individuals to cross-recognize the Omicron spike protein following vaccination or prior infection

Scientists studied the ability of T cells to react with the Omicron spike.

2 Feb 2022

Quantitative framework to investigate the dynamic mechanism of host immune response confronting SARS-CoV-2 infection

The authors highlight that they have created a quantitative framework that allows the dynamic mechanism of the immune response to SARS-CoV-2 to be properly investigated.

2 Feb 2022

Assessing an intranasal lentiviral booster against COVID-19 variants

A new study explores the possibility of vaccination via nasal route utilizing a lentiviral vaccination vector (LV) to be administered as a booster dose against COVID-19.

2 Feb 2022

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Researchers from China summarized the representative structures of SARS-CoV-2 proteins and discussed the development of novel therapeutic agents for targeting these proteins to treat and prevent COVID-19.

2 Feb 2022

Research supports the need for a 3rd mRNA COVID vaccine in patients taking immunosuppressants

New research posted to the medRxiv* preprint server finds patients with immune-mediated inflammatory diseases undergoing anti-TNF therapy had the greatest reduction of antibody levels three months after vaccination. In addition, they had weaker neutralization responses towards severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern.

1 Feb 2022

Scientists develop platform to track SARS-CoV-2 lineages

A team of researchers led by Laura D. Hughes from The Scripps Research Institute in California created an online platform called Outbreak.info to track over 40 million lineages and SARS-CoV-2 mutation across 7,000 locations.

1 Feb 2022

COVID-19 vaccines induce robust cellular immune response against SARS-CoV-2 Omicron

A team of scientists from the United States has recently demonstrated that current coronavirus disease 2019 (COVID-19) vaccines induce robust spike-specific T cell responses against the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

1 Feb 2022

Developing post-vaccination SARS-CoV-2 standard reference sera

A new study reports the generation of reference sera reagents that were obtained from subjects vaccinated with one of four COVID-19 vaccines.

1 Feb 2022

immunity News and Research

Global efforts to track COVID-19 variants grossly underreported a probable variant of concern in Nigeria

CRISPRa method helps discover genes that play a role in immune cell biology

Innate and adaptive immune responses to SARS-CoV-2 in convalescent children and adults

Study describes the first three days of SARS-CoV-2 infection in an ALI model of proximal airway epithelium

A relative COVID-19 survival analysis

Study results strongly support COVID mRNA vaccine boosters for nursing home residents

Antigenic map of SARS-CoV-2 variants reveals amino acid substitutions that govern immune escape and immunodominance

Omicron variant's 'milder' outcomes may be due to more population immunity

Booster dose of Covaxin vaccine candidate neutralizes Omicron and Delta variants

New evidence that positive framing could improve COVID vaccine uptake globally

UK's world-leading human challenge study provides new insights into mild SARS-CoV-2 infections

Study discovers how long-term memory T cells are formed after SARS-CoV-2 exposure

The ability of individuals to cross-recognize the Omicron spike protein following vaccination or prior infection

Quantitative framework to investigate the dynamic mechanism of host immune response confronting SARS-CoV-2 infection

Assessing an intranasal lentiviral booster against COVID-19 variants

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Research supports the need for a 3rd mRNA COVID vaccine in patients taking immunosuppressants

Scientists develop platform to track SARS-CoV-2 lineages

COVID-19 vaccines induce robust cellular immune response against SARS-CoV-2 Omicron

Developing post-vaccination SARS-CoV-2 standard reference sera

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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