covid 19 News and Research

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First anti-SARS Cov2 monoclonal antibody candidate of SpikImm demonstrates excellent tolerance

SPK001, the first anti-SARS Cov2 monoclonal antibody candidate of SpikImm, a French biotechnology company founded by Truffle Capital, originally discovered by the Institut Pasteur's Human Immunology Laboratory, directed by Dr. Hugo Mouquet (Inserm Joint Research Unit), has been tested on three initial cohorts of healthy volunteers, and has demonstrated excellent tolerance, in the context of the Phase 1 clinical study, recently labeled as a "national priority" by CAPNET (National Steering Committee for Therapeutic Trials and other Research on Covid-19).

28 Oct 2022

The impact of seasonal coronavirus immunity on susceptibility to SARS-CoV-2 infection and COVID-19 vaccination

Researchers investigated whether immunity against seasonal human coronavirus spike proteins of HKU1, OC43, NL63, or 229E could protect against SARS-CoV-2 in vitro.

28 Oct 2022

Booster vaccination offered additional protection to residents and staff of California state prisons against SARS-CoV-2 Omicron

Researchers evaluated to what extent prior infection and vaccination protected the residents and staff of the United States California state prison system from breakthrough infection by SARS-CoV-2 Omicron sub-variant B.1.1.529.

28 Oct 2022

Study refutes the nicotinic hypothesis of SARS-CoV-2 infection mechanism

A new study confirmed that the SARS-CoV-2 spike protein does not bind to human AChR’s orthosteric sites, nor does it compete with ACh, choline, or nicotine.

28 Oct 2022

The epigenetic alterations of monocytes in severe COVID-19

Researchers performed DNA methylation analysis on monocytes in the peripheral blood samples obtained from severe COVID-19 patients.

28 Oct 2022

When monkeypox reaches rural communities, it collides with strained public health systems

When a case of monkeypox was reported in Nevada's Humboldt County in August, it was the state's first detected occurrence of the virus in a rural area. Soon, cases were found in other rural counties — Nye, Lyon, and Elko — posing another hurdle for public health systems that have been worn thin by the covid-19 pandemic.

28 Oct 2022

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

Researchers evaluated the concurrent colonization of fungi in the nasopharynx of severe COVID-19 patients.

28 Oct 2022

The dynamics of COVID-19 conspiracist ideation

Researchers studied the dynamics of COVID-19 conspiracist ideation—a general tendency to believe in conspiracy theories.

28 Oct 2022

Overall cancer death rates continue to decline in the United States, says Annual Report to the Nation

Overall cancer death rates continued to decline among men, women, children, and adolescents and young adults in every major racial and ethnic group in the United States from 2015 to 2019, according to the latest Annual Report to the Nation on the Status of Cancer. From 2014 to 2018, overall cancer incidence, or new cases of cancer, remained stable for men and children but increased for women and adolescents and young adults.

28 Oct 2022

Low-density granulocytes are phenotypically altered in people with long-COVID

In a recent study posted to the bioRxiv* preprint server, researchers characterized low-density granulocyte (LDG) neutrophil (NP) proportion among individuals up to 14 months post-SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection.

28 Oct 2022

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

A team of researchers from the United States computationally modified the COV2-2130 monoclonal antibody to restore its neutralizing ability against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants, while retaining efficacy against the Delta and wild-type strains.

27 Oct 2022

An unprecedented list of health-threatening fungi released by the WHO

The WHO fungal priority pathogens list ranks pathogens that pose a serious risk of morbidity and mortality in humans.

27 Oct 2022

New report highlights the health impacts of air pollution in Africa

Nearly all the African continent faces some of the most severe health impacts in the world caused by air pollution, with several countries experiencing some of the highest levels of air pollution in the world, according to a new report published by the U.S.-based research organization Health Effects Institute.

27 Oct 2022

Immune checkpoint therapy may be beneficial in certain cases of severe COVID-19

An article published in Science Advances suggests that a type of cancer treatment known as immune checkpoint blockade may be beneficial in certain cases of severe COVID-19.

27 Oct 2022

Long COVID, a new clinical entity constantly evolving

Researchers discuss the epidemiology, diagnosis, pathogenesis, and treatment of long COVID.

27 Oct 2022

Study sheds new light on the risk of rare blood-clotting condition after covid-19 vaccination

A study published by The BMJ today sheds further light on the risk of developing a very rare blood-clotting condition known as thrombosis with thrombocytopenia syndrome (TTS) after vaccination against the covid-19 virus.

27 Oct 2022

In mild cases of COVID, blood clot risk is higher

Researchers examine the association between COVID-19 and increased cardiovascular outcomes and mortality sequelae.

27 Oct 2022

Increased Gibbs energy of binding indicates greater infectivity of SARS-CoV-2 BA.2.75

Researchers explore the thermodynamic properties of the SARS-CoV-2 Omicron subvariant BA.2.75 to understand its increased transmissibility.

27 Oct 2022

Third dose of COVID-19 mRNA vaccine offers cirrhosis patients strong protection against the virus

Cirrhosis of the liver is associated with decreased responsiveness to many vaccines, including those that protect against COVID-19.

27 Oct 2022

Study examines the severity of the SARS-CoV-2 Omicron BA.2 subvariant

In a recent study that represents the largest to date to examine the severity of the SARS-CoV-2 Omicron BA.2 subvariant (the strain making a re-emergence this fall), a team led by investigators at Massachusetts General Hospital (MGH) determined that the BA.2 subvariant is less severe than the previous Delta variant and less severe to an even greater extent than the original Omicron variant.

27 Oct 2022

covid 19 News and Research

First anti-SARS Cov2 monoclonal antibody candidate of SpikImm demonstrates excellent tolerance

The impact of seasonal coronavirus immunity on susceptibility to SARS-CoV-2 infection and COVID-19 vaccination

Booster vaccination offered additional protection to residents and staff of California state prisons against SARS-CoV-2 Omicron

Study refutes the nicotinic hypothesis of SARS-CoV-2 infection mechanism

The epigenetic alterations of monocytes in severe COVID-19

When monkeypox reaches rural communities, it collides with strained public health systems

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

The dynamics of COVID-19 conspiracist ideation

Overall cancer death rates continue to decline in the United States, says Annual Report to the Nation

Low-density granulocytes are phenotypically altered in people with long-COVID

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

An unprecedented list of health-threatening fungi released by the WHO

New report highlights the health impacts of air pollution in Africa

Immune checkpoint therapy may be beneficial in certain cases of severe COVID-19

Long COVID, a new clinical entity constantly evolving

Study sheds new light on the risk of rare blood-clotting condition after covid-19 vaccination

In mild cases of COVID, blood clot risk is higher

Increased Gibbs energy of binding indicates greater infectivity of SARS-CoV-2 BA.2.75

Third dose of COVID-19 mRNA vaccine offers cirrhosis patients strong protection against the virus

Study examines the severity of the SARS-CoV-2 Omicron BA.2 subvariant

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