Immune System News and Research

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How SARS-CoV-2 proteins affect vascular functionality

The study, published on the pre-print server medRxiv, can pinpoint and isolate how each of the SARS-CoV-2 proteins independently affects the endothelial response and directly gauge endothelial functionality.

3 Mar 2021

Children with MIS-C have highly activated immune systems, study finds

Taking the first deep dive into how the immune system is behaving in patients with multisystem inflammatory syndrome in children (MIS-C), researchers at Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania have found that children with this condition have highly activated immune systems that, in many ways, are more similar to those of adults with severe COVID-19.

2 Mar 2021

Yale researchers identify multiple genes involved in suppression of axon regeneration

When central nervous system cells in the brain and spine are damaged by disease or injury, they fail to regenerate, limiting the body's ability to recover.

2 Mar 2021

A simple blood draw may help discover tumor reactive immune cells to treat advanced melanoma

According to a new study led by Yale Cancer Center and Department of Neurology researchers, a simple blood draw may be the first step in helping to discover tumor reactive immune or T cells to treat advanced melanoma, a deadly form of skin cancer.

2 Mar 2021

Sequential administration of immunotherapy and targeted therapy prolongs anti-tumor responses

Advanced melanoma is one of the deadliest types of cancer, with a 5-year survival rate of only 27% for patients with distant metastases.

2 Mar 2021

Readers and tweeters dispense timely advice for difficult times

Your body’s immune system has produced antibodies that will kill a few thousand kinds of germs and virus. Since you are alive, the chances are quite high you will survive its producing another. Here is how the system works.

2 Mar 2021

Evonik partners with BioNTech to manufacture lipids for COVID-19 vaccine

Caused by SARS-CoV-2, the coronavirus disease 2019 (COVID-19) pandemic continues to spread across the globe.

From Evonik 2 Mar 2021

Experimental therapy delays viral rebound in SHIV-infected macaques

A recent preclinical study by U.S. Military HIV Research Program (MHRP) researchers showed that an experimental therapy combining a TLR7 agonist and two broadly neutralizing antibodies delayed viral rebound in SHIV-infected macaques after antiretroviral therapy (ART) interruption.

2 Mar 2021

Study shows how SARS-CoV-2 affects cytokines compared to other respiratory viruses

Respiratory viruses such as SARS-CoV-2 (causing COVID-19) can often catalyze an overactive immune response that leads to a life-threatening cycle, known as a cytokine storm.

2 Mar 2021

Emerging protein-based immunotherapies could lead to highly effective cancer treatments

In a new commentary for the journal Science, an associate vice president for research at The University of Texas at Arlington argues that emerging protein-based immunotherapies could lead to highly effective "off-the-shelf" cancer treatments for more patients.

1 Mar 2021

Scientists establish infection models for SARS-CoV-2 UK & South African variants

New research suggests Syrian golden hamsters could be a potentially useful preclinical model for testing vaccine immunity against the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.17 and B.1.351 variant.

1 Mar 2021

New vaccination strategy could eliminate the bacteria that cause UTIs

Anyone who has ever developed a urinary tract infection (UTI) knows that it can be painful, pesky and persistent. UTIs have a high recurrence rate and primarily afflict women -- as many as 50% of women will experience at least one UTI during their lifetime.

1 Mar 2021

Study: Highly efficient and balanced immune response key to avoiding COVID-19 symptoms

By analyzing blood samples from individuals infected with SARS-CoV-2, researchers in Singapore have begun to unpack the different responses by the body's T cells that determine whether or not an individual develops COVID-19.

1 Mar 2021

Study could offer a new way to treat Type 1 and Type 2 diabetes

Blocking cell receptors for glucagon, the counter-hormone to insulin, cured mouse models of diabetes by converting glucagon-producing cells into insulin producers instead, a team led by UT Southwestern reports in a new study.

1 Mar 2021

New technique uncovers the tricks used by cancer cells to evade immunotherapies

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients--across cancer types--do not respond, and in most cases, scientists are at a loss as to why.

1 Mar 2021

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers.

1 Mar 2021

A backbone free energy study of SARS-CoV-2 variants of concern

A recent study by scientist Robert Penner at the Institut des Hautes Études Scientifiques in France utilizes free energy calculations to predict effective antiviral targets that are highly conserved, surface-accessible for interaction, and resistant to mutation.

1 Mar 2021

Protein kinase inhibitors could help treat immunodeficiency in HIV patients

HIV infections are treated with antiviral drugs which effectively prevent the disease from developing. While pharmacological HIV therapy has advanced considerably, the virus cannot be entirely eliminated from the body with currently available drugs.

1 Mar 2021

ACGT awards $500,000 to advance immunotherapy approach for treating solid tumors

A scientific team led by Brian Brown, PhD, Professor of Genetics and Genomic Sciences and Associate Director of the Precision Immunology Institute at the Icahn School of Medicine at Mount Sinai (New York, New York), has been awarded $500,000 from Alliance for Cancer Gene Therapy to advance a promising immunotherapy approach to fight lung cancer and other solid tumor cancers.

1 Mar 2021

FDA issues EUA for third COVID-19 vaccine

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the third vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

1 Mar 2021

Immune System News and Research

How SARS-CoV-2 proteins affect vascular functionality

Children with MIS-C have highly activated immune systems, study finds

Yale researchers identify multiple genes involved in suppression of axon regeneration

A simple blood draw may help discover tumor reactive immune cells to treat advanced melanoma

Sequential administration of immunotherapy and targeted therapy prolongs anti-tumor responses

Readers and tweeters dispense timely advice for difficult times

Evonik partners with BioNTech to manufacture lipids for COVID-19 vaccine

Experimental therapy delays viral rebound in SHIV-infected macaques

Study shows how SARS-CoV-2 affects cytokines compared to other respiratory viruses

Emerging protein-based immunotherapies could lead to highly effective cancer treatments

Scientists establish infection models for SARS-CoV-2 UK & South African variants

New vaccination strategy could eliminate the bacteria that cause UTIs

Study: Highly efficient and balanced immune response key to avoiding COVID-19 symptoms

Study could offer a new way to treat Type 1 and Type 2 diabetes

New technique uncovers the tricks used by cancer cells to evade immunotherapies

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

A backbone free energy study of SARS-CoV-2 variants of concern

Protein kinase inhibitors could help treat immunodeficiency in HIV patients

ACGT awards $500,000 to advance immunotherapy approach for treating solid tumors

FDA issues EUA for third COVID-19 vaccine

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