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Exploring evolutionary trajectories of SARS-CoV-2 interacting proteins in bats and primates

Researchers performed high-throughput evolutionary analyses of genes encoding 334 SARS-CoV-2 viral-interacting proteins of modern humans, primates, and bats.

11 Apr 2022

SARS-CoV-2 Omicron BA.2 sublineage outbreak aggravated by low population immunity in Hong Kong

A new study illustrated that inadequate population immunity exacerbated the SARS-CoV-2 Omicron BA.2 sublineage outbreak in Hong Kong.

11 Apr 2022

The human antibody response to the SARS-CoV-2 spike protein N-terminal domain in a group of previously infected individuals

Researchers evaluated the human antibody response to the NTD of the S protein by investigating a group of individuals who had previously been infected with SARS-CoV-2 or who had received an mRNA vaccine.

11 Apr 2022

Ultralong bovine antibody targets cryptic and conserved epitope on SARS-CoV and SARS-CoV-2

Researchers identified an ultralong bovine antibody that neutralizes SARS-CoV-2 and SARS-CoV.

11 Apr 2022

Study explores phytochemical-based antivirals against SARS-CoV-2 infection

A new study depicted plant-based biologically active antiviral agents that are effective against SARS-CoV-2 infection.

11 Apr 2022

Study demonstrates multinuclear MRI is sensitive to functional pulmonary changes in the follow up of patients hospitalized with COVID-19

In this study, researchers subjected patients to a pulmonary 1H and 129Xe MRI protocol at 6, 12, 25, and 50 weeks after hospitalization.

11 Apr 2022

Efficacy of miniaturized electrostatic precipitator respirators in removal of SARS-CoV-2 bioaerosols compared to N95 masks

Researchers developed a prototype of a miniaturized electrostatic precipitator that can be used as an apparatus to effectively remove SARS-CoV-2 containing bioaerosols.

11 Apr 2022

Study explores COVID-19 vaccine hesitancy among those with underlying medical conditions

In a recent study posted to the medRxiv* preprint server, researchers examined the coronavirus disease 2019 (COVID-19) vaccine uptake and hesitancy among people with chronic or severe health conditions.

11 Apr 2022

New research on SARS-CoV-2 Omicron variant mutations and sotrovimab therapy

A recent study posted to the medRxiv* preprint server assessed the impact of sotrovimab treatment on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant-infected immunocompromised (IC) patients.

11 Apr 2022

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

In a recent study posted to the bioRxiv* preprint server, researchers developed aminoadamantane nitrates compounds that inhibit the ion channels formed by the envelope (E) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and enable targeted drug delivery of nitric oxide (NO)-related group for S-nitrosylation of host angiotensin-converting enzyme 2 (ACE2), which would inhibit ACE2 binding with the viral spike (S) protein and thereby inhibit viral replication in the host.

11 Apr 2022

Impact of cardiovascular disease in pregnant or postpartum COVID-19 patients

In a recent study posted to the medRxiv* preprint server, researchers reported coronavirus disease 2019 (COVID-19) prognosis worsened by the presence of cardiovascular diseases (CVDs) in pregnant and postpartum women.

11 Apr 2022

Immunocompromised hosts with Delta/Omicron co-infections

A recent study posted to the medRxiv* preprint server examined clinical cases of co-infections of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta/Omicron variants and Omicron BA.1/ BA.2 sublineages in immunocompromised (IC) patients.

10 Apr 2022

Challenges, unmet needs and future opportunities in COVID-19 therapeutics

In a recent article published in the journal Proceedings of the National Academy of Sciences (PNAS), researchers reviewed the present-day therapeutic landscape of coronavirus disease 2019 (COVID-19) and addressed future opportunities to overcome challenges that hinder drug development and improve the global preparedness for future pandemics.

10 Apr 2022

The effect of unsuppressed HIV on T-cell response to COVID-19

A new study evaluates the impact of HIV infection on SARS-CoV-2 T-cell responses during the first and second waves of COVID-19 in South Africa.

10 Apr 2022

A novel PLpro inhibitor as a broad-spectrum anti-coronavirus agent

Researchers identify a potentially effective compound against COVID-19 against the SARS-CoV-2 PLpro.

10 Apr 2022

CDC report on Omicron infections soon after Delta

A new study identifies ten patients with confirmed SARS-CoV-2 Omicron variant infections within 90 days of a previous Delta variant infection.

10 Apr 2022

Common dishwashing detergents may eliminate coronaviruses from glass

Common dishwashing detergents and scrubbing devices found to be sufficient to inactivate and eliminate human coronaviruses from glass surfaces.

10 Apr 2022

Computational network science approach reveals new mechanisms for coronaviruses infections

A group of bat viruses related to SARS-CoV-2 can also infect human cells but uses a different and unknown entryway.

8 Apr 2022

Substantial SARS-CoV-2 infection in perivascular cells of inflamed blood vessels

A new study demonstrated that vascular inflammation leads to heightened SARS-CoV-2 infection in perivascular cells.

8 Apr 2022

Study finds higher risk of thrombotic events after SARS-CoV-2 infection

A study from Sweden published by The BMJ today finds an increased risk of deep vein thrombosis (a blood clot in the leg) up to three months after covid-19 infection, pulmonary embolism (a blood clot in the lung) up to six months, and a bleeding event up to two months.

8 Apr 2022

SARS News and Research

Exploring evolutionary trajectories of SARS-CoV-2 interacting proteins in bats and primates

SARS-CoV-2 Omicron BA.2 sublineage outbreak aggravated by low population immunity in Hong Kong

The human antibody response to the SARS-CoV-2 spike protein N-terminal domain in a group of previously infected individuals

Ultralong bovine antibody targets cryptic and conserved epitope on SARS-CoV and SARS-CoV-2

Study explores phytochemical-based antivirals against SARS-CoV-2 infection

Study demonstrates multinuclear MRI is sensitive to functional pulmonary changes in the follow up of patients hospitalized with COVID-19

Efficacy of miniaturized electrostatic precipitator respirators in removal of SARS-CoV-2 bioaerosols compared to N95 masks

Study explores COVID-19 vaccine hesitancy among those with underlying medical conditions

New research on SARS-CoV-2 Omicron variant mutations and sotrovimab therapy

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

Impact of cardiovascular disease in pregnant or postpartum COVID-19 patients

Immunocompromised hosts with Delta/Omicron co-infections

Challenges, unmet needs and future opportunities in COVID-19 therapeutics

The effect of unsuppressed HIV on T-cell response to COVID-19

A novel PLpro inhibitor as a broad-spectrum anti-coronavirus agent

CDC report on Omicron infections soon after Delta

Common dishwashing detergents may eliminate coronaviruses from glass

Computational network science approach reveals new mechanisms for coronaviruses infections

Substantial SARS-CoV-2 infection in perivascular cells of inflamed blood vessels

Study finds higher risk of thrombotic events after SARS-CoV-2 infection

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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