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Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

A new paper deals with the identification of an antiviral compound that could help in developing additional drugs to help fight COVID-19.

30 Nov 2021

Study finds early stages of sarcopenia could be counteracted with timely interventions

Weakening muscles are a natural part of the ageing process, but for some people with a condition called sarcopenia the decline is abnormally fast.

30 Nov 2021

Prevalence of type 2 diabetes is elevated in people with a psychiatric disorder

A new study published in Diabetologia (the journal of the European Association for the Study of Diabetes (EASD)) finds that the prevalence of type 2 diabetes (T2D) is elevated in people with a psychiatric disorder compared with the general population.

30 Nov 2021

Industrially processed foods increase the risk of a second heart attack or a fatal stroke

Ultra-processed foods are a major public health concern for their potential adverse effects on health. Now a study by the Department of Epidemiology and Prevention of the I.R.C.C.S. Neuromed in Pozzilli (Italy) explores the health effects of a large dietary share of ultra-processed food on people already suffering from cardiovascular diseases.

30 Nov 2021

Study: About 1 in 100 COVID-19 patients likely develop central nervous system complications

The largest multi-institutional international study to date on brain complications of COVID-19 has found that approximately one in 100 patients hospitalized with COVID-19 will likely develop complications of the central nervous system.

29 Nov 2021

Study finds atazanavir inhibits main SARS-CoV-2 protease

Research shows that ATV has different antiviral activity compared to PAXLOVID™, encouraging further research.

29 Nov 2021

Viral RNA in the blood found to be a reliable indicator of COVID-19 mortality risk

The amount of a SARS-CoV-2 genetic material-;viral RNA-;in the blood is a reliable indicator in detecting which patients will die of the disease, a team led by Université de Montréal medical professor Dr. Daniel Kaufmann has found.

26 Nov 2021

Prediction of severe infection based on SARS-CoV-2 genomic analysis

A group of researchers have used these SARS-CoV-2 sequence data and developed an algorithm to predict severity based upon viral mutations.

26 Nov 2021

Effects of social class, ethnicity, and gender on burden of COVID-19 mortality

The researchers determined if opportunities for remote work correlated with COVID-19 deaths for sociodemographic groups.

26 Nov 2021

SARS-CoV-2 vaccine based on vesicular stomatitis virus exhibits high neutralizing efficacy against variants

Scientists have tested the efficacy of BriLife®-vaccinated human sera in neutralizing more infectious and probably more virulent SARS-CoV-2 variants.

26 Nov 2021

Extreme heat effects may be more pronounced among young and middle-aged adults than older adults

Extreme heat-;a leading cause of weather-related deaths in the United States-;poses an increasing threat to the public, as days of extreme heat are expected to become more frequent, more intense, and longer-lasting due to the continued effects of climate change.

25 Nov 2021

Key to controlling COVID-19 is early intervention

A study published in the journal Royal Society Open Science demonstrates the critical role of timely intervention in New Zealand's success story. The researchers used a stochastic branching process model to simulate the trajectory of COVID-19 transmission and control during New Zealand's 2020 outbreak. They calculated the number of reported cases and deaths and the probability of elimination within a defined time frame.

25 Nov 2021

COVID-19 became more lethal in the U.K. in late 2020, statistical analysis suggests

A new statistical analysis supports beliefs that COVID-19 became more lethal in the U.K. in late 2020, while also suggesting that multiple factors-;not just the alpha variant of the virus that causes COVID-19-;were to blame.

25 Nov 2021

Researchers map how far HIV patients live from access to care

In sub-Saharan Africa, 7 million people with HIV live more than 10 minutes from health care services and 1.5 million people with HIV live more than 60 minutes from a healthcare facility, according to a new study published this week in the open-access journal PLOS Global Public Health by Diego Cuadros of the University of Cincinnati, and colleagues.

25 Nov 2021

New AI predictive algorithm greatly improves timeliness and accuracy of sepsis predictions

Each year, sepsis affects more than 30 million people worldwide, causing an estimated six million deaths. Sepsis is the body's extreme response to an infection and is often life-threatening.

25 Nov 2021

Direct-acting antivirals for HCV-related hepatocellular carcinoma reduces the risk of tumor progression

In a new cohort study of patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), a disease with a high recurrence rate, researchers at the Osaka City University Graduate School of Medicine reported that after receiving cancer treatment, the oral administration of direct-acting antivirals (DAA) reduces the risk of tumor progression following recurrence of the liver disease.

25 Nov 2021

Scientists link increased air pollution to an uptick in cases of lung cancer

An international team of scientists, led by Nanyang Technological University, Singapore (NTU Singapore), has linked increased air pollution to an uptick in cases of lung adenocarcinoma (LADC) worldwide.

25 Nov 2021

Maternal-fetal interface yields intriguing clues to how it battles SARS-CoV-2

Scientists have hypothesized that the number of immune cells and the amount of cytokines produced in response to SARS-CoV-2 infection in pregnant women change in accordance with the timing of maternal infection in pregnancy. This study is available on the bioRxiv* preprint server.

24 Nov 2021

Innovative algorithm predicts COVID-related intensive care unit resource use

The COVID-19 pandemic is on the rise in many European countries, and hospitals world wide are under maximum pressure.

24 Nov 2021

SARS-CoV-2 reinfection and the natural immune response

Researchers review available literature on immunity and SARS-CoV-2 infection to elucidate mechanisms behind SARS-CoV-2 immunity and reinfections.

24 Nov 2021

Mortality News and Research

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

Study finds early stages of sarcopenia could be counteracted with timely interventions

Prevalence of type 2 diabetes is elevated in people with a psychiatric disorder

Industrially processed foods increase the risk of a second heart attack or a fatal stroke

Study: About 1 in 100 COVID-19 patients likely develop central nervous system complications

Study finds atazanavir inhibits main SARS-CoV-2 protease

Viral RNA in the blood found to be a reliable indicator of COVID-19 mortality risk

Prediction of severe infection based on SARS-CoV-2 genomic analysis

Effects of social class, ethnicity, and gender on burden of COVID-19 mortality

SARS-CoV-2 vaccine based on vesicular stomatitis virus exhibits high neutralizing efficacy against variants

Extreme heat effects may be more pronounced among young and middle-aged adults than older adults

Key to controlling COVID-19 is early intervention

COVID-19 became more lethal in the U.K. in late 2020, statistical analysis suggests

Researchers map how far HIV patients live from access to care

New AI predictive algorithm greatly improves timeliness and accuracy of sepsis predictions

Direct-acting antivirals for HCV-related hepatocellular carcinoma reduces the risk of tumor progression

Scientists link increased air pollution to an uptick in cases of lung cancer

Maternal-fetal interface yields intriguing clues to how it battles SARS-CoV-2

Innovative algorithm predicts COVID-related intensive care unit resource use

SARS-CoV-2 reinfection and the natural immune response

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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