Transplant News and Research

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Wearable skin patch could help clinicians diagnose tumors, organ malfunction and more

Novel skin patch capable of deep detection of hemoglobin and core temperature.

22 Dec 2022

Mutations responsible for common inherited heart condition corrected using CRISPR-Cas9 therapy

Using the CRISPR-Cas9 gene editing system, UT Southwestern researchers corrected mutations responsible for a common inherited heart condition called dilated cardiomyopathy (DCM) in human cells and a mouse model of the disease.

21 Dec 2022

Research could pave way for designing more strategically engineered transplants to treat cartilage damage in the joints

A collaborative team, which includes scientists from the Terasaki Institute for Biomedical Innovation, University of Illinois Chicago, and Pohang University of Science and Technology has elucidated some key points on how the generation of cartilage in the joints is facilitated and how alternative bone formation can be avoided.

21 Dec 2022

Developing stem cell sheet for enhancement of angiogenesis which promotes cardiac repair

Myocardial infarction is an ischemic disease in which a coronary artery supplying blood to the heart muscle is stenotic or obstructed, resulting in cardiac tissue necrosis.

16 Dec 2022

Study shows how a specific gut microbe-generated byproduct is linked to heart failure risk

New research at Cleveland Clinic expands the link between what we eat and how the gut microbiome impacts our susceptibility to develop different diseases – in this case, how a specific gut microbe-generated byproduct is linked to heart failure risk.

16 Dec 2022

Four genetic mutations linked to progressive multifocal leukoencephalopathy

New research has confirmed a strong link between four genetic mutations and progressive multifocal leukoencephalopathy (PML), a rare but often fatal brain infection that can be triggered by dozens of FDA-approved drugs.

14 Dec 2022

Study finds bebtelovimab therapy lacks efficacy in patients infected with SARS-CoV-2 Omicron subvariants

Researchers assessed the impact of bebtelovimab (BEB) monoclonal antibody in the treatment of high-risk SARS-CoV-2 Omicron variant-infected patients.

13 Dec 2022

Targeted therapies and novel drug combinations show promise for the treatment of multiple leukemias

Researchers from The University of Texas MD Anderson Cancer Center are presenting compelling findings from three clinical trials at the 2022 American Society of Hematology Annual Meeting.

13 Dec 2022

GOSH delivers world-first base-edited cell therapy for a patient with relapsed T cell leukemia

A patient with relapsed T cell leukemia has been given base-edited T-cells in a world-first use of a base-edited cell therapy, in a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children (GOSH).

12 Dec 2022

A-HIPI decision model can predict survival in adults with advanced-stage Hodgkin lymphoma

Investigators from Rutgers Cancer Institute of New Jersey, the state's only NCI-designated Comprehensive Cancer Center and leading cancer program along with Tufts Medical Center in Boston, developed and validated the Advanced-stage Hodgkin lymphoma International Prognostication Index (A-HIPI).

12 Dec 2022

For patients with sickle cell disease, fertility care is about reproductive justice

Teonna Woolford has always wanted six kids. Why six? "I don't know where that number came from. I just felt like four wasn't enough," said Woolford, a Baltimore resident. "Six is a good number."

8 Dec 2022

UHN’s Ajmera Transplant Centre performed a groundbreaking parathyroid transplant

The Ajmera Transplant Centre at University Health Network (UHN) has performed a groundbreaking parathyroid transplant, in a patient who suffered from a severe form of hypoparathyroidism – when there is little or no parathyroid function.

5 Dec 2022

Study: 40% of websites for heart transplant centers lack information in languages other than English

In a University of Michigan-led study, researchers found that most websites for heart transplant centers in the United States are difficult to understand, with more than 40% lacking information in languages other than English.

30 Nov 2022

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

Recently, scientists reviewed the role of sulforaphane from cruciferous vegetables (e.g., broccoli) in preventing IBD by regulating inflammation and altering the gut microbiome.

29 Nov 2022

World Antimicrobial Awareness Week 2022: What is the burden of antimicrobial resistance?

As part of World Antimicrobial Resistance Week 2022, News-Medical speaks to Dr. Tomislav Meštrović about his new research discussing the burden of bacterial antimicrobial resistance in the WHO European region, as well as about how we can prevent antimicrobial resistance together.

24 Nov 2022

Additional mRNA COVID vaccine doses could salvage antibody responses in blood cancer patients

A third COVID-19 vaccine dose in this patients with blood cancers could enhance their antibody responses against SARS-CoV-2

21 Nov 2022

Rutgers scientists develop new approach to effectively shut down viral infections

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.

20 Nov 2022

Caregivers’ coping strategies affect their level of distress and quality of life

November is Caregiver Awareness Month, and timely findings from a study published in Blood Advances suggest that, among caregivers of patients undergoing a stem cell transplant, how someone approaches coping can influence their levels of anxiety, depression, and poor quality of life (QOL) they experience.

20 Nov 2022

IESC transplant could repair the intestinal barrier after stroke and improve outcomes

Stroke is a leading cause of death, dementia and serious long-term disability. According to the American Heart Association, stroke patients also have a greater risk of depression, which negatively affects functional and cognitive recovery.

20 Nov 2022

Study analyzes left digit bias in organ donors entering a new decade of age

American transplant centers as well as organ procurement organizations, the groups responsible for recovering organs from deceased donors in the United States, were less likely to accept or select organs from donors who were 70 years old when they died compared to those who were 69, new research found.

17 Nov 2022

Transplant News and Research

Wearable skin patch could help clinicians diagnose tumors, organ malfunction and more

Mutations responsible for common inherited heart condition corrected using CRISPR-Cas9 therapy

Research could pave way for designing more strategically engineered transplants to treat cartilage damage in the joints

Developing stem cell sheet for enhancement of angiogenesis which promotes cardiac repair

Study shows how a specific gut microbe-generated byproduct is linked to heart failure risk

Four genetic mutations linked to progressive multifocal leukoencephalopathy

Study finds bebtelovimab therapy lacks efficacy in patients infected with SARS-CoV-2 Omicron subvariants

Targeted therapies and novel drug combinations show promise for the treatment of multiple leukemias

GOSH delivers world-first base-edited cell therapy for a patient with relapsed T cell leukemia

A-HIPI decision model can predict survival in adults with advanced-stage Hodgkin lymphoma

For patients with sickle cell disease, fertility care is about reproductive justice

UHN’s Ajmera Transplant Centre performed a groundbreaking parathyroid transplant

Study: 40% of websites for heart transplant centers lack information in languages other than English

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

World Antimicrobial Awareness Week 2022: What is the burden of antimicrobial resistance?

Additional mRNA COVID vaccine doses could salvage antibody responses in blood cancer patients

Rutgers scientists develop new approach to effectively shut down viral infections

Caregivers’ coping strategies affect their level of distress and quality of life

IESC transplant could repair the intestinal barrier after stroke and improve outcomes

Study analyzes left digit bias in organ donors entering a new decade of age

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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