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Stabilizing the long-term endemic behavior of COVID-19

Researchers used a classic age and contact structured model to explore the several reopening and vaccination coverage scenarios regarding the COVID-19 pandemic.

21 Dec 2021

Younger cancer patients at particularly increased risk of mortality from COVID-19

Systematic reviews and meta-analysis were conducted to identify the impact of SARS-CoV-2 in cancer patients based on tumor type, age, and treatment, and any novel risk factors for COVID-19 in cancer patients

21 Dec 2021

Understanding SARS-CoV-2-induced systemic amyloidosis

A new study proposed that inflammation combined with aggregates of amyloidogenic peptides of SARS-CoV-2 S proteins might induce systemic amyloidosis.

21 Dec 2021

Identifying a recurring pattern in broadly neutralizing antibodies that can target an epitope on SARS-CoV-2

Interesting research decrypts a recurring sequence in antibodies against severe acute respiratory syndrome 2 (SARS-CoV-2) and identifies it to be a board neutralizing antibody that targets a conserved epitope on the SARS-CoV-2 receptor-binding domain (RBD) of the spike protein.

21 Dec 2021

Risk of hospitalization for infants and children with COVID-19 below 1%

Children are a low-risk group for COVID-19 following infection with SARS-CoV-2, with less than 2% of European hospitalizations with the disease being in children below the age of 19.

21 Dec 2021

Children with isolated symptoms as likely as those with multiple symptoms to test COVID-19 positive

A new study compares rates of coronavirus disease 2019 infection in children who reported no symptoms, one isolated symptom, or two or more symptoms during the circulation of the Delta variant.

21 Dec 2021

Efficacy of the mRNA-1273 vaccine against emerging COVID-19 variants

A new study emphasized the effectiveness of two doses of mRNA-1273 in preventing infection with SARS-CoV-2 and hospital admission with covid-19 due to variants including delta.

21 Dec 2021

Estimating vaccine efficacy against COVID-like illness from omicron and other COVID-19 variants

A new study combines real-time syndromic surveillance data from daily cross-sectional surveys with a COVID-like illness (CLI) prevalence-based vaccine efficacy estimator to better explain the early onset of the omicron variant.

21 Dec 2021

New method to detect SARS-CoV-2 helps get reliable results more quickly

You're worried that you may have been exposed to the coronavirus, so you decide to take a test. But which do you choose?

21 Dec 2021

Researchers create 'UV Curtain' that can sterilize rooms against coronaviruses

Researchers from the Ludwig Maximilian University of Munich have created a new system to protect areas from the virus, using a light-emitting diode (LED)-based ultraviolet C (UV-C) light curtain. Specific wavelengths of UV-C are known to inactivate viruses and bacteria, and this tool could help keep areas sterile.

20 Dec 2021

Booster shots improve CD8+ T cell response to SARS-CoV-2 in animal model

In a new study, published on the bioRxiv* preprint server, scientists showed in a mice model that three doses of the same synthetic peptide vaccine, eliciting an exclusive CD8+ T cell response against one SARS-CoV-2 Spike epitope, protected against lethal SARS-CoV-2 infection, in the absence of neutralizing antibodies. Researchers also showed that the third dose resulted in superior generation of effector-memory T cells in the circulation and tissue-resident memory T (TRM) cells.

20 Dec 2021

An Omicron wave predicted for England from December 2021 to April 2022

A study, published on the medRxiv* preprint server, focuses on the interaction between Omicron variants and public health interventions in England that promote immunity.

20 Dec 2021

Researchers find a digital silver lining in failed COVID-19 drug trial

A clinical trial in which two test drugs failed to help patients with mild COVID-19 nevertheless had a silver lining: It proved the viability of a study model in which a medication's potential arrhythmic side effects are safely, effectively monitored without the participants ever setting foot in a hospital or clinic.

20 Dec 2021

New oral pill for COVID-19 home treatment

As cases and hospitalizations continue to rise in many countries, new treatments are being sought to arrest the progression of the disease, preventing severe illness and death or disability. One such is the small molecule molnupiravir, the focus of a new research paper.

20 Dec 2021

QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis

A new study posted to the bioRxiv* preprint server aimed to demonstrate whether the loss of the QTQTN motif attenuates SARS-CoV-2 replication in respiratory cells in vitro and pathogenesis in hamsters.

20 Dec 2021

New study suggests most monoclonal antibody treatments are ineffective against Omicron SARS-CoV-2 variant

The arrival of the Omicron (B.1.1.529) variant has brought into question the effectiveness of current COVID-19 treatments in preventing infection and death. New research published in the preprint bioRxiv* server suggests the efficacy of most monoclonal antibody treatments are ineffective against Omicron.

20 Dec 2021

Scientists develop first photo-electrochemical aptasensor to detect SARS-CoV-2 virus in saliva

Scientists at the Universidad Carlos III de Madrid (UC3M) have developed the first photo-electrochemical aptasensor that detects the SARS-CoV-2 virus in a saliva sample.

20 Dec 2021

New Omicron variant may be better at evading vaccine-induced antibodies, research shows

The Omicron variant of SARS-CoV-2 may be significantly better than previous variants at evading vaccine-induced antibodies, according to new research from Cambridge - but preliminary evidence suggests it is less likely to cause severe COVID-19 illness in the lungs.

20 Dec 2021

Omicron variant of SARS-CoV-2 exhibits striking antibody evasion

Researchers discuss the likely impact on current convalescent therapies and immunity of vaccinated individuals against the SARS-CoV-2 Omicron variant.

20 Dec 2021

Lung memory B-cells provide primary protection against SARS-CoV-2 reinfection

Researchers study influenza and SARS-CoV-2 infection models to identify lung memory B cells during viral infection.

20 Dec 2021

SARS News and Research

Stabilizing the long-term endemic behavior of COVID-19

Younger cancer patients at particularly increased risk of mortality from COVID-19

Understanding SARS-CoV-2-induced systemic amyloidosis

Identifying a recurring pattern in broadly neutralizing antibodies that can target an epitope on SARS-CoV-2

Risk of hospitalization for infants and children with COVID-19 below 1%

Children with isolated symptoms as likely as those with multiple symptoms to test COVID-19 positive

Efficacy of the mRNA-1273 vaccine against emerging COVID-19 variants

Estimating vaccine efficacy against COVID-like illness from omicron and other COVID-19 variants

New method to detect SARS-CoV-2 helps get reliable results more quickly

Researchers create 'UV Curtain' that can sterilize rooms against coronaviruses

Booster shots improve CD8+ T cell response to SARS-CoV-2 in animal model

An Omicron wave predicted for England from December 2021 to April 2022

Researchers find a digital silver lining in failed COVID-19 drug trial

New oral pill for COVID-19 home treatment

QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis

New study suggests most monoclonal antibody treatments are ineffective against Omicron SARS-CoV-2 variant

Scientists develop first photo-electrochemical aptasensor to detect SARS-CoV-2 virus in saliva

New Omicron variant may be better at evading vaccine-induced antibodies, research shows

Omicron variant of SARS-CoV-2 exhibits striking antibody evasion

Lung memory B-cells provide primary protection against SARS-CoV-2 reinfection

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