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Assay for the identification of SARS-CoV-2 Spike reactive T and B cells

An interesting new paper presents a new assay for B and T lymphocytes in individuals infected with SARS-CoV-2.

14 Dec 2021

Evaluating the exclusion of unvaccinated people in the prevention of SARS-CoV-2 transmission

New study results suggest that the numbers needed to exclude model and baseline infection risk could be key indicators of the drawbacks and benefits of vaccine mandates and vaccine passports.

14 Dec 2021

Risk of SARS-CoV-2 reinfection in children compared to adults

The current study aimed to explore the rate and risk of SARS-CoV-2 reinfections in children.

14 Dec 2021

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

A group of researchers from various institutions developed a nucleoside-modified mRNA vaccine that encodes the SARS-CoV-2 N protein (mRNA-N) and is formulated in lipid nanoparticles for this investigation (LNP).

14 Dec 2021

Machine learning method for determining impact of mutations in the SARS-CoV-2 RBD on binding and antibody escape

Deep mutational learning (DML) is a technique developed by researchers from multiple institutions that combines experimental yeast display screening of RBD mutagenesis libraries with deep sequencing and machine learning.

14 Dec 2021

SARS-CoV-2 transmission through indoor aerosols

A recent review published in the International Journal of Indoor Environment and Health presents the science behind the person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an indoor environment.

14 Dec 2021

Phenome study reveals alternate associations with SARS-CoV-2 risk loci

Researchers from the Duke Molecular Physiology Institute have been investigating genetic associations with more severe disease and examining the associations that certain genetic features have with other diseases.

13 Dec 2021

New prototype enables people with severely impaired motor skills to communicate with others

A research team from the University of Malaga has developed a prototype that combines scalp sensors and a graphical interface to enable people with severely impaired motor skills to communicate with others.

13 Dec 2021

Omicron variant may strike double vaccinated

Largely, scientists are skeptical that the Omicron variant can infect vaccinated individuals. However, a new study published on the medRxiv* preprint server has conducted neutralization assays using an Omicron isolate obtained from patients residing in the United Kingdom.

13 Dec 2021

Determination of the effectiveness of COVID-19 vaccination using T cell receptor repertoire

A new study published on the bioRxiv preprint server has hypothesized that T cell receptors (TCR) repertoire can measure the response to vaccines, as it would identify the TCR of clones that respond to the vaccination.

13 Dec 2021

CRISPR-Cas enzyme-based diagnostics to detect SARS-CoV-2 infection

A recent review in the journal Life provided a detailed description of CRISPR-Cas-based diagnostic techniques to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but also emphasized the potential use of this technology towards developing effective molecular diagnostic platforms for any future pandemic.

13 Dec 2021

A model-based evaluation on the effectiveness of social distancing in COVID

Researchers utilize a mathematical model-based analysis to assess how social distancing measures contained the COVID-19 pandemic and reduced mortality.

13 Dec 2021

Characteristics of vaccine breakthroughs in fully vaccinated individuals in France with delta variant

In a recent observational study, scientists have described the characteristics of VBIs in fully vaccinated individuals in France.

13 Dec 2021

Study offers new hope for large B-cell lymphoma patients

Of the 18,000 people diagnosed with large B-cell lymphoma each year, only half will be successfully treated with chemotherapy. The 9,000 remaining patients typically have poor outcomes, with only 25% responding to additional, higher-intensity chemotherapy, followed by a stem cell transplant.

13 Dec 2021

New England research on population immunity and SARS-CoV-2

A new study discusses a model-based reconstruction of SARS-CoV-2 attack rate and population-immunity curves for three New England states.

13 Dec 2021

Iota-carrageenan inhibits replication of SARS-CoV-2 VOCs

Scientists have recently reported the efficacy of carrageenan against both the SARS-CoV-2 original strain as well as the Alpha, Beta, Gamma, and Delta VOCs.

13 Dec 2021

Novel assay using finger-prick samples provides COVID-19 vaccine efficacy data

Researchers estimate vaccine efficacy over a period post-vaccination using quantitative antibody assay on finger-prick blood samples.

13 Dec 2021

Glycans strengthen interaction between viral spike proteins and ACE2 receptors on host cells

A new study shows that the ACE2 and RBD of coronavirus spike fragments have different binding strengths and dissociation rates when they are glycosylated and non-glycosylated.

13 Dec 2021

Evaluating the virucidal activity of blue LED light against SARS-CoV-2 infection

A new study provides some possible explanations to the mechanisms by which antiviral activity is exerted by blue LED light and indicated that the alteration of the SARS-CoV-2 spike protein requires the presence of photosensitizers.

13 Dec 2021

Impact of tumor environments on susceptibility and course of disease in those infected with SARS-CoV-2

A review assessed the impact of "hot" vs. "cold" immune/tumor environments (and associated therapies) on susceptibility and disease course in subjects with these two types of tumors and infected with SARS-CoV-2 to decipher the mechanisms that drive these adverse outcomes in COVID-19 infected cancer patients.

13 Dec 2021

Syndrome News and Research

Assay for the identification of SARS-CoV-2 Spike reactive T and B cells

Evaluating the exclusion of unvaccinated people in the prevention of SARS-CoV-2 transmission

Risk of SARS-CoV-2 reinfection in children compared to adults

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

Machine learning method for determining impact of mutations in the SARS-CoV-2 RBD on binding and antibody escape

SARS-CoV-2 transmission through indoor aerosols

Phenome study reveals alternate associations with SARS-CoV-2 risk loci

New prototype enables people with severely impaired motor skills to communicate with others

Omicron variant may strike double vaccinated

Determination of the effectiveness of COVID-19 vaccination using T cell receptor repertoire

CRISPR-Cas enzyme-based diagnostics to detect SARS-CoV-2 infection

A model-based evaluation on the effectiveness of social distancing in COVID

Characteristics of vaccine breakthroughs in fully vaccinated individuals in France with delta variant

Study offers new hope for large B-cell lymphoma patients

New England research on population immunity and SARS-CoV-2

Iota-carrageenan inhibits replication of SARS-CoV-2 VOCs

Novel assay using finger-prick samples provides COVID-19 vaccine efficacy data

Glycans strengthen interaction between viral spike proteins and ACE2 receptors on host cells

Evaluating the virucidal activity of blue LED light against SARS-CoV-2 infection

Impact of tumor environments on susceptibility and course of disease in those infected with SARS-CoV-2

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