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Researchers observe how two proteins operate at tricellular junctions

Organs in animals and in humans have one thing in common: they are bounded by so-called epithelial cells.

27 Aug 2020

Study may help develop new types of non-addictive pain therapies

A team of scientists from ASU's School of Molecular Sciences and the Biodesign Institute have recently published a study in Nature Communications that helps clarify the contributions to an ion channel's temperature - dependent activation. This in turn should aid in the development of new types of non-addictive pain therapies.

27 Aug 2020

Advances in Virus Epigenetics

Growing evidence shows viruses exploit epigenetic processes to control their life cycles but epigentic regulation of viral infections is not fully understood.

From Chromatrap® - Porvair Sciences Ltd 25 Aug 2020

Scientists unravel how nanomaterials inspired by insect wings destroy superbugs

Scientists have revealed how nanomaterials inspired by insect wings are able to destroy bacteria on contact.

25 Aug 2020

Single dose nasal vaccine against SARS-CoV-2 shows promise in animal studies

Now researchers at the Washington University School of Medicine in St. Louis have worked on developing a candidate vaccine against the infection that could be administered in a single dose via a nasal spray rather than an injection. In their preliminary studies using lab mice, this single dose of the nasal vaccine successfully prevented the infection with the novel coronavirus.

24 Aug 2020

Researchers discover new mechanism for anticancer drug resistance in gastric cancer

A joint project led by Kumamoto University (Japan) has discovered a new mechanism for anticancer drug resistance in gastric cancer.

21 Aug 2020

Study shows how foodborne pathogen infects a human intestinal cell

As soon as the foodborne pathogen Vibrio parahaemolyticus infects a human intestinal cell, the bacteria are already planning their escape.

18 Aug 2020

New technique enables real-time observation of influenza A hemagglutinin during viral entry

Unlike living organisms, to avoid extinction, viruses need to hijack living host machineries to generate new viruses.

17 Aug 2020

Targeting SARS-CoV-2 with off-the-shelf CAR-NK cells

The current COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread and cause disease and death in many countries even today. At present, there is no effective treatment. A recent study published on the preprint server bioRxiv in August 2020 reports the potential of a new class of drugs called CAR NK cells, which could be used off-the-shelf to treat this disease.

17 Aug 2020

Membrane nanoparticles acts as a bait to trap SARS-CoV-2

In an exciting new bioRxiv preprint research paper, Chinese researchers describe the development of membrane nanoparticles from ACE2-rich cells with a potent capacity to block the adherence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

13 Aug 2020

Study reveals the genetic cause of congenital malformation

Study by the University of Bonn reveals that genetic information controls development of the urinary tract, rectum and genitals Spontaneous mutations of a single gene are likely to cause serious developmental disorders of the excretory organs and genitalia.

7 Aug 2020

New alpha-radioimmunotherapy for multiple myeloma shows promise in preclinical study

A new alpha-radioimmunotherapy, 212Pb-anti-CD38, has proven effective in preventing tumor growth and increasing survival in multiple myeloma tumor-bearing mice, according to new research published in the July issue of the Journal of Nuclear Medicine. Given the long half-life, central production and worldwide distribution of 212Pb-anti-CD38, researchers have determined that the α-radioimmunotherapy is not only effective but also clinically feasible as a multiple myeloma treatment.

6 Aug 2020

Avidity of binding responsible for cross-neutralization of SARS-CoV-1 and SARS-CoV-2

In a new study published on the preprint server bioRxiv researchers characterized the crystal structure of the antibody-SARS-CoV-2 RBD complex in an attempt to find the epitope and the mechanism that enables cross-neutralization.

5 Aug 2020

De novo protein decoys that block SARS-CoV-2

Now, a new study published on the preprint server bioRxiv in August 2020 shows that computational design technology can be efficiently harnessed towards this end, producing new molecules to inhibit viral entry and replication.

5 Aug 2020

Novel technology tests the presence of thin membrane protrusions on breast cancer cells

Researchers at the University of Maryland School of Medicine (UMSOM) have developed a novel technology to test for the presence of thin membrane protrusions called "microtentacles" on breast cancer cells, which can help predict whether a tumor is likely to spread.

5 Aug 2020

Novel mutation identified in SARS-CoV-2 spike protein from Sweden

Researchers from Sweden and Brazil have identified a novel mutation in a strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) obtained from a patient in Stockholm, Sweden, in late April.

4 Aug 2020

Scientists develop human lung organoids to study SARS-CoV-2 infection

Now, a new study published on the preprint server bioRxiv in July 2020 reports the development of a human distal lung culture system that can be functionally tested. This will help not only to understand how this infection produces disease but also to test the proliferative capacity of the stem cells in this part of the body.

30 Jul 2020

High ACE2 Expression on pancreatic islet cells during inflammation could explain new-onset diabetes in COVID-19

A new study suggests that the SARS-CoV-2 infection may be linked to the onset of diabetes, via the infection of pancreatic islet beta cells, which produce insulin.

27 Jul 2020

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

Vesigen Therapeutics to develop and commercialize novel drug-delivery technologies

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

Cell Membrane News and Research

Researchers observe how two proteins operate at tricellular junctions

Study may help develop new types of non-addictive pain therapies

Advances in Virus Epigenetics

Scientists unravel how nanomaterials inspired by insect wings destroy superbugs

Single dose nasal vaccine against SARS-CoV-2 shows promise in animal studies

Researchers discover new mechanism for anticancer drug resistance in gastric cancer

Study shows how foodborne pathogen infects a human intestinal cell

New technique enables real-time observation of influenza A hemagglutinin during viral entry

Targeting SARS-CoV-2 with off-the-shelf CAR-NK cells

Membrane nanoparticles acts as a bait to trap SARS-CoV-2

Study reveals the genetic cause of congenital malformation

New alpha-radioimmunotherapy for multiple myeloma shows promise in preclinical study

Avidity of binding responsible for cross-neutralization of SARS-CoV-1 and SARS-CoV-2

De novo protein decoys that block SARS-CoV-2

Novel technology tests the presence of thin membrane protrusions on breast cancer cells

Novel mutation identified in SARS-CoV-2 spike protein from Sweden

Scientists develop human lung organoids to study SARS-CoV-2 infection

High ACE2 Expression on pancreatic islet cells during inflammation could explain new-onset diabetes in COVID-19

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

Vesigen Therapeutics to develop and commercialize novel drug-delivery technologies

Pioneering Live Cell Imaging - Yokogawa's Impact and Innovations

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

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