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New 'reporter viruses' make it easier to observe SARS-CoV-2 in real time

A version of SARS-CoV-2, the virus that causes COVID-19 disease, has been successfully modified to glow brightly in cells and animal tissues, providing a real-time way to track the spread and intensity of viral infection as it happens in animal models, researchers at Texas Biomedical Research Institute report in the journal The Proceedings of the National Academy of Sciences.

27 Sep 2021

Researchers discover protein previously unknown to be involved in SARS-CoV-2 infection

Researchers in the UK and Germany have provided evidence for a novel mechanism by which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – binds to human host cells.

27 Sep 2021

Drug treatment decreases risk for severe COVID-19 outcomes in patients with Type 2 diabetes

A type of drug already used to treat obesity and Type 2 diabetes, when taken six months prior to the diagnosis of COVID-19, was associated with a decreased risk of hospitalization, respiratory complications and death in COVID-19 patients with Type 2 diabetes, according to researchers at Penn State College of Medicine.

27 Sep 2021

An in-depth assessment into origin and spread of SARS-CoV-2 Delta variant in Brazil

Brazilian researchers characterize the dissemination of the Delta VOC in Brazil and assess its emergence within the global Delta phylogeny.

27 Sep 2021

Third COVID-19 mRNA vaccine booster dose indicated for myelofibrosis patients

A new study discusses the utility of a third booster dose in patients with myelofibrosis.

27 Sep 2021

Monoclonal antibodies may reduce hospital stay, but not mortality in COVID-19

A new study explores the real-world efficacy of monoclonal antibodies against COVID-19 in averting severe disease.

27 Sep 2021

Chronic COVID-19 and divergent variants of SARS-CoV-2

A new study discusses the isolation of two variants of concern (VOCs) from an immunocompromised COVID-19 patient.

27 Sep 2021

Trial of Sanofi/GSK SARS-CoV-2 vaccine boosters against variants in non-human primates

New research discusses the development of soluble prefusion-stabilized spike trimers (CoV2 preS dTM) comprising adjuvant AS03.

27 Sep 2021

A new SARS-CoV-2 variant (B.1.1.523) capable of escaping immune protections

A new study describes a new variant that possesses a novel combination of various concerning mutations at the spike region.

27 Sep 2021

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

A new review article investigates the clinical and viral characteristics, pathogenesis, as well as human genetic basis associated with COVID-19.

27 Sep 2021

Researchers develop new method for rapidly detecting SARS-CoV-2 RNA

DTU-researchers develop a novel method for rapidly detecting SARS-CoV-2 RNA that may also be designed to detect other diseases.

27 Sep 2021

Limited evidence colchicine reduces COVID-19 related hospitalization

The present randomized clinical trial attempted to study if colchicine will effectively hasten recovery and reduce COVID-19 associated hospitalizations or death.

27 Sep 2021

Hyperbranched polylysine nanopolymer as potential broad-spectrum antiviral against SARS-CoV-2

The findings from this study suggest that HPNs may inhibit viral replication and budding.

27 Sep 2021

Characterization of SARS-CoV-2 infections diagnosed after mRNA BNT162b2 vaccination

A team from the National Institute for Infectious Diseases “L. Spallanzani” (INMI) has recently reported their study on 94 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections (47.9% symptomatic, 52.1% asymptomatic) that occurred after the first or second vaccine dose against SARS-CoV-2 in the Lazio region (Central Italy).

27 Sep 2021

SARS-CoV-2 entry inhibitors show antiviral activity

A new study used a combination of a computer-aided drug design approach and cell-based in vitro assays to identify five potential SARS-CoV-2 inhibitors.

27 Sep 2021

Irish meat processing plant COVID-19 outbreak: a retrospective study

A new study involved a retrospective investigation of the outbreak of COVID-19 in an Irish meat plant.

27 Sep 2021

Design of peptide vaccine for SARS-CoV-2

In a recent study, researchers from the US identified two immunogenic non-structural proteins - PLpro and RdRp - from immunodominant gene regions ORF1ab, ORF3a and ORF9b as potential targets for a vaccine against SARS-CoV-2.

27 Sep 2021

B cell activating anti-CD73 antibody for the immunotherapy of COVID-19

Despite the advent of numerous vaccines and the discovery of passive monoclonal antibodies for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), there remains an urgent need for definitive therapies for coronavirus disease-2019 (COVID-19) patients.

27 Sep 2021

Study suggests two doses of COVID-19 vaccine may offer some protection for kidney transplant patients

Researchers from Toronto, Canada, performed a cohort study to analyze the impact of COVID-19 vaccination on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and clinical outcomes in kidney transplant patients. This study is available on the preprint server, medRxiv.

27 Sep 2021

SARS-CoV-2 infection less severe in children and youth during first part of the pandemic

New research has found that children and youth may be at low risk of severe acute COVID-19, according to a study conducted during the first half of the pandemic and published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.210053.

27 Sep 2021

SARS News and Research

New 'reporter viruses' make it easier to observe SARS-CoV-2 in real time

Researchers discover protein previously unknown to be involved in SARS-CoV-2 infection

Drug treatment decreases risk for severe COVID-19 outcomes in patients with Type 2 diabetes

An in-depth assessment into origin and spread of SARS-CoV-2 Delta variant in Brazil

Third COVID-19 mRNA vaccine booster dose indicated for myelofibrosis patients

Monoclonal antibodies may reduce hospital stay, but not mortality in COVID-19

Chronic COVID-19 and divergent variants of SARS-CoV-2

Trial of Sanofi/GSK SARS-CoV-2 vaccine boosters against variants in non-human primates

A new SARS-CoV-2 variant (B.1.1.523) capable of escaping immune protections

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

Researchers develop new method for rapidly detecting SARS-CoV-2 RNA

Limited evidence colchicine reduces COVID-19 related hospitalization

Hyperbranched polylysine nanopolymer as potential broad-spectrum antiviral against SARS-CoV-2

Characterization of SARS-CoV-2 infections diagnosed after mRNA BNT162b2 vaccination

SARS-CoV-2 entry inhibitors show antiviral activity

Irish meat processing plant COVID-19 outbreak: a retrospective study

Design of peptide vaccine for SARS-CoV-2

B cell activating anti-CD73 antibody for the immunotherapy of COVID-19

Study suggests two doses of COVID-19 vaccine may offer some protection for kidney transplant patients

SARS-CoV-2 infection less severe in children and youth during first part of the pandemic

Exploring the G:Box and for high-quality imaging

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How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

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