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Huge Malaria vaccine trial in Malawi

This week the African nation of Malawi became one of the first of the planned three to launch a pilot trial for a novel vaccine against malaria. The news and the efforts were lauded by the World Health Organization (WHO).

24 Apr 2019

Uncovering the Structure of HIV Integrase to Inform Drug Discovery

In this interview Dr Kushol Gupta, Research Assistant Professor in the Department of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania talks to News-Medical and Life Sciences about the importance of light scattering techniques for investigating structure and mechanism of action in his ongoing research into HIV integrase and the development of HIV therapeutics.

From Waters | Wyatt Technology 24 Apr 2019

Key research takeaways from ECCMID 2019

This article aims to provide a brief overview of the key themes of the 29th ECCMID conference and update readers on current research projects.

From ESCMID 19 Apr 2019

As syphilis invades rural America, a fraying health safety net is failing to stop it

When Karolyn Schrage first heard about the "dominoes gang" in the health clinic she runs in Joplin, Mo., she assumed it had to do with pizza.

19 Apr 2019

Scientists identify rare, paradoxical response to antiretroviral therapy

Antiretroviral therapy is usually very effective at suppressing HIV in the body, allowing a person's immune system to recover by preventing the virus from destroying CD4+ T cells.

19 Apr 2019

Breakthrough antibody treatment suppresses HIV without antivirals

A new research paper describes how an antibody that prevents HIV binding to human immune cells was shown to be able to suppress levels of HIV for up to four months.

18 Apr 2019

C-Path and CDISC release global Therapeutic Area Standard for HIV research

The Critical Path Institute and CDISC are pleased to announce the release of a global Therapeutic Area Standard that specifies how to structure commonly collected data and outcome measurements in clinical trials for HIV.

17 Apr 2019

Keto diet - for the military, aging and epilepsy

Ketogenic diet or keto diet has been in the news as a trending diet option for weight watchers and those who wish to lose those extra pounds.

17 Apr 2019

Researchers develop novel recombinant vaccine against Nipah virus

Nipah virus is a type of RNA virus transmitted from animals to humans. The infection causes severe respiratory illness and symptoms including cough, headache and fever, which can progress into encephalitis, seizure and coma.

15 Apr 2019

Spotlight on ECCMID 2019: Detecting Disease & Managing Infections

This article covers some of the highlights of ECCMID 2019, with insights into some of the companies and products being featured at the event.

From ESCMID 15 Apr 2019

New technique uses UV and red light to decontaminate organs before transplantation

A new technique for the decontamination of organs before transplantation using ultraviolet and red light irradiation has been developed by Brazilian and Canadian researchers and is described in an article published in the journal Nature Communications.

12 Apr 2019

Increased neutrophil lifespan may contribute to intestinal inflammation in HIV-infected individuals

The increased survival of white blood cells called neutrophils is associated with alterations in the intestinal microbiome of HIV-infected individuals, according to a study published April 11 in the open-access journal PLOS Pathogens by Nichole Klatt of the University of Miami, and colleagues.

11 Apr 2019

Sexual behavior could affect gut microbiome and immune system

A person's sexual behavior could affect their microbiome and immune system, potentially elevating their risk of HIV infection, according to a new study from researchers at the University of Colorado Anschutz Medical Campus.

10 Apr 2019

HPV vaccination rates are low, especially in HIV prone populations

HPV vaccination rates in populations at high-risk of contracting HIV are particularly low, increasing the risk of HPV and HIV co-infection.

10 Apr 2019

Teens exploring sexuality online experience health and safety risks

Teens spend hours every day on internet-connected devices, where limitless opportunities to explore sexuality online.

10 Apr 2019

FDA approves two-drug complete regimen for previously untreated HIV-infected adults

The U.S. Food and Drug Administration today approved Dovato (dolutegravir and lamivudine), as a complete regimen for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults with no antiretroviral treatment history and with no known or suspected substitutions associated with resistance to the individual components of Dovato.

9 Apr 2019

Novel models and strategies for TB detection, elimination, and care

This week, publication of a special issue on tuberculosis begins in PLOS Medicine, advised by guest editors Richard Chaisson of Johns Hopkins University, Claudia Denkinger of the University of Heidelberg, and Mark Hatherill of the South African Tuberculosis Vaccine Institute.

8 Apr 2019

Gut microbiome may drive HIV transmission risk in high-risk men

Gut microbes from high HIV-risk men who have sex with men drive immune activation in mice and HIV infection in cells, according to a study published April 4 in the open-access journal PLOS Pathogens by Brent Palmer and Catherine Lozupone of the University of Colorado Anschutz, and colleagues.

8 Apr 2019

New HIV drug that is like a "Swiss Army knife of immunotherapies"

HIV is a tricky virus that causes a unique phenomenon where the virus hides within the immune cells of patients when they are on treatment with the antiretroviral therapy (ART) drugs. When they are off the drugs, the virus comes back.

7 Apr 2019