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Pilot study assesses antibody response to third COVID-19 vaccine dose in kidney transplant recipients

A pilot study has begun to assess the antibody response to a third dose of an authorized COVID-19 mRNA vaccine in kidney transplant recipients who did not respond to two doses of the Moderna or Pfizer-BioNTech COVID-19 vaccine.

10 Aug 2021

Study shows impaired SARS-CoV-2 mRNA vaccine antibody response in individuals with chronic conditions

A recent study in Colorado used real-world data to evaluate if individuals with chronic conditions have reduced antibody response to COVID-19 mRNA vaccines. The study investigated whether some medical conditions may impact antibody response to the mRNA vaccines.

9 Aug 2021

Polymer-based coating for blood vessels can reduce organ rejection following a transplant

Researchers have found a way to reduce organ rejection following a transplant by using a special polymer to coat blood vessels on the organ to be transplanted.

9 Aug 2021

COVID-19 vaccination offers significant protection for solid organ transplant recipients

In a Brief Communication, published July 29, 2021 in the journal Transplant Infectious Disease, a team of physician-scientists at University of California San Diego School of Medicine found that solid organ transplant recipients who were vaccinated experienced an almost 80 percent reduction in the incidence of symptomatic COVID-19 compared to unvaccinated counterparts during the same time.

5 Aug 2021

Scientists urge increased attention to persistent COVID-19 infections in immunocompromised people

In an article in the New England Journal of Medicine, scientists from Fred Hutchinson Cancer Research Center, Johns Hopkins Bloomberg School of Medicine, the U.S. Military HIV Research Program and the Institute for Global Health and Infectious Diseases at the University of North Carolina urged increased attention to persistent COVID-19 infections in immunocompromised people.

5 Aug 2021

Immunocompromised patients could be potential hosts for immune-escape mutants of SARS-CoV-2

In a recently published article in The New England Journal of Medicine, scientists have described how multi-mutational variants of SARS-CoV-2 may evolve in patients with immunosuppression.

5 Aug 2021

Artificial pancreas may soon help patients with type 2 diabetes

An artificial pancreas could soon help people living with type 2 diabetes and who also require kidney dialysis. Tests led by the University of Cambridge and Inselspital, University Hospital of Bern, Switzerland, show that the device can help patients safely and effectively manage their blood sugar levels and reduce the risk of low blood sugar levels.

4 Aug 2021

Research: Only 26% of areas in the UK have an effective pathway in place for early liver disease detection

New research published today in a peer review journal shows only 26% of areas in the UK have an effective pathway in place for the early detection of liver disease.

4 Aug 2021

Start codon disruption with CRISPR-Cas9 gene editing prevents Fuchs’ corneal dystrophy in mice

In a new study, researchers at the University of Oregon's Phil and Penny Knight Campus for Accelerating Scientific Impact used start codon disruption with CRISPR-Cas9 gene editing to prevent Fuchs' corneal dystrophy in mice.

3 Aug 2021

Study reveals cellular basis of antigen-specific response to Pfizer-BioNTech’s COVID-19 vaccine

Researchers in the United States have provided important insights into the antigen-specific cellular response and evolving humoral (antibody) response to messenger RNA- (mRNA) based vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

29 Jul 2021

Immunity to SARS-CoV-2 in renal transplant and dialysis patients using Pfizer/BioNTech and Moderna vaccines

A study analyzes the immune responses of medical personnel, as well as immunocompromised DP and immunosuppressed KTR patients.

27 Jul 2021

Impaired immune response to SARS-CoV-2 mRNA vaccination in immunocompromised patients

A new study describes how immunocompromised vaccine recipients may not always respond as expected to the COVID-19 vaccine.

27 Jul 2021

Researchers warn against relaxing Covid-19 restrictions prematurely

Relaxing Covid-19 restrictions could pave the way for new vaccine-resistant virus mutations – according to researchers at the University of East Anglia and the Earlham Institute.

27 Jul 2021

Study reveals disparities in heart failure diagnosis within clinical practices

Many heart failure diagnoses may be missed in a primary care setting. Women, Black adults and individuals with lower net worth are significantly more likely to be diagnosed with heart failure in an acute care setting such as the emergency room or during a hospitalization, even if they reported symptoms of heart failure during a routine, outpatient health care appointment during the previous six months, according to new research published today in Circulation: Heart Failure, an American Heart Association journal.

27 Jul 2021

Pre-transplant cardio-cerebrovascular diseases impact hematopoietic cell transplant outcomes

Hematopoietic cell transplantation (HCT) is a recognized treatment option for certain blood and bone marrow cancers as well as some autoimmune and hereditary disorders.

23 Jul 2021

Llama ‘nanobodies’ have the potential to outwit human cytomegalovirus

Scientists have developed a 'nanobody' - a small fragment of a llama antibody - that is capable of chasing out human cytomegalovirus (HCMV) as it hides away from the immune system.

22 Jul 2021

Analysis: Necessary or not, covid booster shots are probably on the horizon

The drugmaker Pfizer recently announced that vaccinated people are likely to need a booster shot to be effectively protected against new variants of covid-19 and that the company would apply for Food and Drug Administration emergency use authorization for the shot.

21 Jul 2021

Transplant News and Research

Pilot study assesses antibody response to third COVID-19 vaccine dose in kidney transplant recipients

Study shows impaired SARS-CoV-2 mRNA vaccine antibody response in individuals with chronic conditions

Polymer-based coating for blood vessels can reduce organ rejection following a transplant

COVID-19 vaccination offers significant protection for solid organ transplant recipients

Scientists urge increased attention to persistent COVID-19 infections in immunocompromised people

Immunocompromised patients could be potential hosts for immune-escape mutants of SARS-CoV-2

Artificial pancreas may soon help patients with type 2 diabetes

Research: Only 26% of areas in the UK have an effective pathway in place for early liver disease detection

Start codon disruption with CRISPR-Cas9 gene editing prevents Fuchs’ corneal dystrophy in mice

Study reveals cellular basis of antigen-specific response to Pfizer-BioNTech’s COVID-19 vaccine

Immunity to SARS-CoV-2 in renal transplant and dialysis patients using Pfizer/BioNTech and Moderna vaccines

Impaired immune response to SARS-CoV-2 mRNA vaccination in immunocompromised patients

Researchers warn against relaxing Covid-19 restrictions prematurely

Study reveals disparities in heart failure diagnosis within clinical practices

Pre-transplant cardio-cerebrovascular diseases impact hematopoietic cell transplant outcomes

Llama ‘nanobodies’ have the potential to outwit human cytomegalovirus

Analysis: Necessary or not, covid booster shots are probably on the horizon

Maternal fecal transplant may help restore gut microbiota in newborns with diabetes risk

CEPI and IVI announce new research program to expand access to COVID-19 vaccines in Africa

Deadly spider venom could help prevent damage from heart attacks

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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