Ribonucleic Acid News and Research

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N-dihydrogalactochitosan shows promise as a mucosal vaccine adjuvant against SARS-CoV-2

In a recent study posted to the bioRxiv* server, researchers in the United States demonstrated the efficacy of a novel biopolymer, N-dihydrogalactochitosan (GC), as an adjuvant for next-generation mucosal coronavirus disease 2019 (COVID-19) vaccine.

12 Sep 2022

Small molecule inhibitor found to be effective against SARS-CoV-2 variants

In a new study, researchers developed RK-33, a small molecule inhibitor of DDX3, and evaluated its efficacy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs).

12 Sep 2022

BNT162b2 SARS-CoV-2 vaccinations found to reduce incidence of long COVID symptoms

Researchers assessed the association between Pfizer-BioNTech’s SARS-CoV-2 BNT162b2 messenger ribonucleic acid (mRNA) vaccination and the incidence of post-COVID-19 symptoms among Israeli adults.

12 Sep 2022

Role of the transketolase-like 1 gene in the development of the modern human brain

In a new study, researchers demonstrated how transketolase-like 1 (TKTL1) gene expression influenced neocortical neurogenesis in modern humans.

12 Sep 2022

Interferon response induced by Omicron BA.1 and BA.5 prevents influenza A infection

In a recent study posted to the bioRxiv* preprint server, researchers in Germany and the United Kingdom investigated the interferon responses induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant and SARS-CoV-2 Omicron sub-variants BA.1 and BA.5, and their efficacy in protecting cells from influenza A virus super-infection.

12 Sep 2022

Self-replicating intradermal RNA vaccine against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers assessed the efficiency of a controllable self-replicating ribonucleic acid (c-srRNA) vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

12 Sep 2022

A direct side-by-side comparison of all available COVID-19 vaccines

In a recent study posted to the medRxiv* preprint server, researchers assessed immune responses to homologous and heterologous coronavirus disease 2019 (COVID-19) vaccine combinations among Córdoba, Spain residents.

11 Sep 2022

Antibody escape less pronounced with BA.2.75 compared to BA.4/5

In a recent study published in the Lancet, researchers evaluated the antibody neutralization sensitivity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2.75 subvariant.

11 Sep 2022

Novel method for gene editing of hPSCs yields up to 84% knockout efficiency

A Penn State-led team of interdisciplinary researchers has developed techniques to improve the efficiency of CRISPR-Cas9, the genome editing technique that earned the Nobel Prize in 2020.

9 Sep 2022

Promising anti-cancer agent may also prevent SARS-CoV-2 from replication

Based on findings from a new study by a Johns Hopkins Medicine-led research team, an effective means of fighting SARS-CoV-2, the virus that causes COVID-19, may be possible that circumvents the problem of waning immunity often observed when current vaccines deal with emerging COVID variants.

8 Sep 2022

How does previous SARS-CoV-2 infection impact the B cell receptor repertoire in response to vaccination?

Researchers evaluated immune responses by B lymphocytes to Pfizer’s severe acute respiratory syndrome coronavirus 2 mRNA vaccine.

8 Sep 2022

How can Legionella pneumophila transmit through the hot water plumbing of residences and office buildings?

Researchers investigate the transmission of the causative agent of legionellosis, Legionella pneumophila, through hot water plumbing systems in commercial and residential buildings.

8 Sep 2022

How does SARS-CoV-2 infection and vaccination impact human immune memory?

Researchers review current knowledge regarding the generation of immune memory responses and their durability post-infection and vaccination.

7 Sep 2022

How does SARS-CoV-2 affect the male genitourinary system?

In a recent paper published in the American Journal of Clinical and Experimental Urology, researchers reviewed existing data on the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on the male genitourinary (GU) tract.

7 Sep 2022

How does SARS-CoV-2 infection impact fertility in men?

In a recent review published in the journal Endocrines, researchers summarized existing literature findings on the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on the male reproductive system and fertility.

7 Sep 2022

NIH animal study combines Paxlovid with Lagevrio against SARS-CoV-2 Delta

In a recent study posted to the bioRxiv* preprint server, researchers at the U.S National Institutes of Health demonstrated the efficacy of molnupiravir and nirmatrelvir, two oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals in the rhesus macaque model, the closest proxy to humans.

7 Sep 2022

Techniques used for SARS-CoV-2 detection in body fluids

In a recent review published in the journal Trends in Analytical Chemistry, researchers provided a comprehensive overview of the current techniques used for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection in bodily fluids.

7 Sep 2022

The associations between vaccination status, type, and time since vaccination with lineage identity during the emergence of new SARS-CoV-2 variants

Researchers assessed the association between SARS-CoV-2 strains and patient age, COVID-19 vaccination status, vaccine type, and days elapsed since the most recent vaccination among New York residents.

7 Sep 2022

Photocatalyst-based ViraMap platform maps SARS-CoV-2 spike protein interactions on the cell surface

Researchers performed the photocatalytic mapping of the SARS-CoV-2 spike protein-host cell membrane interactions.

7 Sep 2022

The prevalence, genetic diversity, and evolution of SARS-CoV-2 in white-tailed deer in New York

Researchers investigated the prevalence, genomic diversity, and evolution of SARS-CoV-2 among white-tailed deers in New York.

6 Sep 2022

Ribonucleic Acid News and Research

N-dihydrogalactochitosan shows promise as a mucosal vaccine adjuvant against SARS-CoV-2

Small molecule inhibitor found to be effective against SARS-CoV-2 variants

BNT162b2 SARS-CoV-2 vaccinations found to reduce incidence of long COVID symptoms

Role of the transketolase-like 1 gene in the development of the modern human brain

Interferon response induced by Omicron BA.1 and BA.5 prevents influenza A infection

Self-replicating intradermal RNA vaccine against SARS-CoV-2

A direct side-by-side comparison of all available COVID-19 vaccines

Antibody escape less pronounced with BA.2.75 compared to BA.4/5

Novel method for gene editing of hPSCs yields up to 84% knockout efficiency

Promising anti-cancer agent may also prevent SARS-CoV-2 from replication

How does previous SARS-CoV-2 infection impact the B cell receptor repertoire in response to vaccination?

How can Legionella pneumophila transmit through the hot water plumbing of residences and office buildings?

How does SARS-CoV-2 infection and vaccination impact human immune memory?

How does SARS-CoV-2 affect the male genitourinary system?

How does SARS-CoV-2 infection impact fertility in men?

NIH animal study combines Paxlovid with Lagevrio against SARS-CoV-2 Delta

Techniques used for SARS-CoV-2 detection in body fluids

The associations between vaccination status, type, and time since vaccination with lineage identity during the emergence of new SARS-CoV-2 variants

Photocatalyst-based ViraMap platform maps SARS-CoV-2 spike protein interactions on the cell surface

The prevalence, genetic diversity, and evolution of SARS-CoV-2 in white-tailed deer in New York

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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