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Researchers report high rates of new TB infection among adolescents in Tanzania

Published today in PLOS ONE, "Serial T-SPOT.TB responses in Tanzanian adolescents: transient, persistent and irregular conversions" [https://doi.org/10.1371/journal.pone.0268685], investigators from the Geisel School of Medicine and Muhimibili University of Health and Allied Sciences report high rates of new tuberculosis (TB) infection among adolescents in Tanzania.

24 Jun 2022

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

A recent article posted to the bioRxiv* preprint server identified numerous efficacious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies from convalescent SARS-CoV-2 patients.

23 Jun 2022

New method helps unravel three-dimensional structure of the human genome

Weill Cornell Medicine and New York Genome Center researchers, in collaboration with Oxford Nanopore Technologies, have developed a new method to assess on a large scale the three-dimensional structure of the human genome, or how the genome folds.

23 Jun 2022

Novel liquid biopsy test can quickly identify cancer DNA in patients with metastatic breast cancer

A novel, automated liquid biopsy test in development by researchers at the Johns Hopkins Kimmel Cancer Center can accurately detect the presence of cancer DNA in the blood of patients with metastatic breast cancer within five hours.

23 Jun 2022

U-M researchers reveal how a mutated protein acts as risk factor in Parkinson’s disease

In about a fifth of the cases of Parkinson’s disease, look to a small, malfunctioning protein in the lysosome as a risk factor, say University of Michigan researchers.

23 Jun 2022

The effect of immunization with bivalent oral poliovirus vaccine on the incidence of COVID-19

Researchers evaluated the impact of the OPV on the incidence of COVID-19.

23 Jun 2022

Implications of impaired type I interferon immunity and increasing COVID-19 severity

Researchers demonstrated that impaired type I interferon immunity is associated with increasing coronavirus disease 2019 severity.

20 Jun 2022

Scientists explore brainstem circuits to find nausea intervention strategies

In a new study, researchers uncovered the organization of nausea-associated brainstem circuits to show that selectively blocking the excitatory neurons responsive to nausea-promoting growth/differentiation factor 15 suppresses nausea-related behaviors.

20 Jun 2022

SARS-CoV-2 spike circulating in most long COVID 12 months post-diagnosis

In a recent study posted to the medRxiv* preprint server, researchers explored the association between circulating coronavirus disease 2019 (COVID-19) antigens and post-COVID-19 sequelae (long COVID).

20 Jun 2022

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

Researchers reported on the misclassification of the SARS-CoV-2 Omicron BA.1 subvariant as Omicron BA.2 subvariant in an automated variant-specific polymerase chain reaction analysis.

17 Jun 2022

Scientists explore effectiveness of neutralizing antibodies against SARS-CoV-2 Omicron variant

Researchers assessed the impact of SARS-CoV-2-neutralizing antibodies on the SARS-CoV-2 Omicron variant.

17 Jun 2022

Demonstrating varying pathogenicity and tropism of SARS-CoV-2 variants in a feline model

In a recent study posted to the bioRxiv* pre-print server, researchers at Cornell University College of Veterinary Medicine and the University of Illinois Urbana-Champaign compared the infection dynamics, pathogenicity, and tissue tropism of multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants in adult cats.

17 Jun 2022

Novel luminescent biosensor detects SARS-CoV-2 spike protein using cell phone camera

In a recent study posted to the bioRxiv* pre-print server, researchers developed a novel Binding Activated Tandem split enzyme (BAT) biosensor for the detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein.

16 Jun 2022

Glucose meter can detect SARS-CoV-2 antibodies in patient samples

Over-the-counter COVID tests can quickly show whether you are infected with SARS-CoV-2. But if you have a positive result, there's no equivalent at-home test to assess how long you're protected against reinfection.

16 Jun 2022

New liquid biopsy assay enables prediction of treatment response in patients with esophageal cancer

Biomarkers are like the X on a treasure map, but instead of indicating the location of unearthed riches, they indicate an individual's health status.

16 Jun 2022

UB program secures $12.8 million to improve the quality of global HIV research

The National Institutes of Health (NIH) has awarded $12.8 million to the University at Buffalo School of Pharmacy and Pharmaceutical Sciences to lead a clinical pharmacology quality assurance program for NIH-funded laboratories and research networks across the globe conducting HIV and infectious disease research.

16 Jun 2022

Effectiveness of a hybrid vaccine against COVID-19 and influenza

Researchers assessed the efficiency of a hybrid vaccine against influenza and COVID-19 viruses.

16 Jun 2022

Research suggests profound SARS-CoV-2 mutations are rare even among immunosuppressed

A recent article posted to the medRxiv* preprint server assessed whether host traits like immunosuppression aids severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutational drift.

16 Jun 2022

Nasopharyngeal microbiota influences SARS-CoV-2 infection status and severity

In a recent study posted to the medRxiv* pre-print server, Canadian researchers investigated how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection altered the microbiota composition of the host’s nasopharyngeal region.

16 Jun 2022

Multiomics identifies genomic risk factors for COVID-19

In a recent Cell Systems study, researchers utilized the RefMap machine learning algorithm to correlate known genomic variations for severe COVID-19 obtained from large-scale genome-wide association studies (GWAS) with single-cell multiome profiling of human lungs.

16 Jun 2022

Assay News and Research

Researchers report high rates of new TB infection among adolescents in Tanzania

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

New method helps unravel three-dimensional structure of the human genome

Novel liquid biopsy test can quickly identify cancer DNA in patients with metastatic breast cancer

U-M researchers reveal how a mutated protein acts as risk factor in Parkinson’s disease

The effect of immunization with bivalent oral poliovirus vaccine on the incidence of COVID-19

Implications of impaired type I interferon immunity and increasing COVID-19 severity

Scientists explore brainstem circuits to find nausea intervention strategies

SARS-CoV-2 spike circulating in most long COVID 12 months post-diagnosis

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

Scientists explore effectiveness of neutralizing antibodies against SARS-CoV-2 Omicron variant

Demonstrating varying pathogenicity and tropism of SARS-CoV-2 variants in a feline model

Novel luminescent biosensor detects SARS-CoV-2 spike protein using cell phone camera

Glucose meter can detect SARS-CoV-2 antibodies in patient samples

New liquid biopsy assay enables prediction of treatment response in patients with esophageal cancer

UB program secures $12.8 million to improve the quality of global HIV research

Effectiveness of a hybrid vaccine against COVID-19 and influenza

Research suggests profound SARS-CoV-2 mutations are rare even among immunosuppressed

Nasopharyngeal microbiota influences SARS-CoV-2 infection status and severity

Multiomics identifies genomic risk factors for COVID-19

eBook: Using iPSCs models for human disease research and drug discovery eBook

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Automating research - solutions and best practices

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