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Durable selenium nanoparticle fabrics with antiviral and antibacterial properties

Researchers graft SeNPs on polyester fabric through a flat screen-printing technique and observed their antimicrobial activity.

8 Mar 2022

Study evaluates heterologous vaccination scheme in children using two SARS-CoV-2 RBD protein vaccines

A recent study predicted the efficacy of the SOBERANA 02 and SOBERANA Plus COVID-19 vaccines in children.

8 Mar 2022

Study explores immune escape mutations caused by prolonged viral shedding in immunocompromised COVID-19 patient

A new study examined a unique case of extended viral shedding in an immunocompromised patient that produced a series of SARS-CoV-2 immune escape mutations over a seven-month period.

8 Mar 2022

Omicron-based vaccine candidate generated to assess whether immunogenicity could be further improved

Researchers developed a vaccine candidate termed Ad26.COV2.S.529, encoding a stabilized Omicron-based S protein resembling ancestral SARS-CoV-2 Wuhan-Hu-1 S protein.

8 Mar 2022

Thermostable next-generation vaccine candidate against SARS-CoV-2 variants of concern studied in mice

Researchers developed a highly thermo-tolerant vaccine candidate that elicited high nAb titers in mice against several SARS-CoV-2 variants of concerns.

8 Mar 2022

Identification of a rapid test for SARS-CoV-2 neutralization via antibodies and nanobodies

Researchers presented a technique called rapid in vitro inhibition assay (RIVIA), whereby potential SARS-CoV-2 antibody and nanobody candidates can be rapidly screened.

8 Mar 2022

Comparative immunogenicity of reduced and standard BNT162b2 and mRNA-1273 boosters in CoronaVac vaccinees

Researchers compared the immunogenicity of the reduced and standard doses of the BNT162b2 and mRNA-1273 vaccine in adults immunized with two doses of the CoronaVac vaccine.

8 Mar 2022

Orbit Discovery and WuXi AppTec sign agreement to access peptide discovery and optimisation technologies

Orbit Discovery is pleased to announce the commencement of a partnership with WuXi AppTec, a leading global provider of R&D and manufacturing services.

8 Mar 2022

SARS-CoV-2 variant identification by RT-qPCR assays targeting mutations

In a recent study posted to the medRxiv* preprint server, researchers investigated the efficacy of diagnostic tests for identifying severe acute respiratory syndrome coronavirus (SARS-CoV-2) variants of concern (VOCs).

8 Mar 2022

Development of RT-qPCR assays for differentiating SARS-CoV-2 Omicron BA.1 and BA.2 variants

In a recent study posted to the medRxiv*preprint server, a team of researchers from Israel developed and validated novel reverse transcriptase - quantitative polymerase chain reaction (RT-qPCR) assays. The new assays enable the rapid and high throughput identification and differentiation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 and BA.2 variants.

8 Mar 2022

Higher SARS-CoV-2 load in morning-collected samples

In a recent study posted to the medRxiv* preprint server, researchers identified that morning-collected nasal and saliva samples yielded better detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), especially in tests with low to moderate analytical sensitivity.

8 Mar 2022

Study reveals the potential of novel antiviral drug combinations to stop COVID-19 spread

Researchers from Columbia Engineering, Fiocruz's Center for Technological Development in Health and the Oswaldo Cruz Institute in Brazil, Memorial Sloan Kettering Cancer Center, and Rockefeller University recently reported that, by combining inhibitors of polymerases and exonucleases--enzymes that allow SARS-CoV-2 to reproduce--they were able to reduce SARS-CoV-2 replication 10 times more than when using just the polymerase inhibitors.

7 Mar 2022

SARS-CoV-2 breakthrough infection leads to distinct neutralizing antibody response

Scientists hypothesize that antibody-specific responses vary during vaccine breakthrough infections in a variant-specific manner.

7 Mar 2022

Delta and Omicron coinfections identified in France

A new study shows both the Omicron and Delta variants were able to infect patients with healthy immune function.

7 Mar 2022

Identification of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding

Researchers discovered compounds able to inhibit SARS-CoV-2 macrodomain 1 and adenosine diphosphate-ribose binding via high throughput screening.

7 Mar 2022

Binding efficacy of SARS-CoV-2 S1 specific salivary antibodies to the Omicron and Delta variants

A recent study assessed the varying affinities of SARS-CoV-2 antibodies to the SARS-CoV-2 Omicron and Delta variants of concern in vaccinated and convalescent individuals.

7 Mar 2022

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

Researchers develop an Omicron variant mRNA vaccine that is be more potent in generating nAbs as compared to other available vaccines.

6 Mar 2022

RT-LAMP assay shows promise as point-of-care SARS-CoV-2 detection assay across multiple settings

Researchers evaluate the feasibility and robustness of an optimized RT-LAMP SARS-CoV-2 detection assay across multiple resource-restricted settings.

4 Mar 2022

COVID-19 and the life sciences; what have we learned and where are we going?

News-Medical attended the 2022 SLAS press briefing where Peter Simpson, Michael Girardi, and Simon Meffan-Main gave their thoughts on the life sciences sector post-COVID-19.

From Society for Laboratory Automation and Screening (SLAS) 4 Mar 2022

Lipidomic profiling may provide early prediction of type 2 diabetes and cardiovascular disease risk

Simultaneous measurement of dozens of types of fats in the blood ("lipidomics") can predict the risk of developing type 2 diabetes (T2D) and cardiovascular disease (CVD) years in the future, according to a new study publishing March 3rd in the open-access journal PLOS Biology from Chris Lauber of Lipotype, Germany, and colleagues.

3 Mar 2022

Assay News and Research

Durable selenium nanoparticle fabrics with antiviral and antibacterial properties

Study evaluates heterologous vaccination scheme in children using two SARS-CoV-2 RBD protein vaccines

Study explores immune escape mutations caused by prolonged viral shedding in immunocompromised COVID-19 patient

Omicron-based vaccine candidate generated to assess whether immunogenicity could be further improved

Thermostable next-generation vaccine candidate against SARS-CoV-2 variants of concern studied in mice

Identification of a rapid test for SARS-CoV-2 neutralization via antibodies and nanobodies

Comparative immunogenicity of reduced and standard BNT162b2 and mRNA-1273 boosters in CoronaVac vaccinees

Orbit Discovery and WuXi AppTec sign agreement to access peptide discovery and optimisation technologies

SARS-CoV-2 variant identification by RT-qPCR assays targeting mutations

Development of RT-qPCR assays for differentiating SARS-CoV-2 Omicron BA.1 and BA.2 variants

Higher SARS-CoV-2 load in morning-collected samples

Study reveals the potential of novel antiviral drug combinations to stop COVID-19 spread

SARS-CoV-2 breakthrough infection leads to distinct neutralizing antibody response

Delta and Omicron coinfections identified in France

Identification of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding

Binding efficacy of SARS-CoV-2 S1 specific salivary antibodies to the Omicron and Delta variants

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

RT-LAMP assay shows promise as point-of-care SARS-CoV-2 detection assay across multiple settings

COVID-19 and the life sciences; what have we learned and where are we going?

Lipidomic profiling may provide early prediction of type 2 diabetes and cardiovascular disease risk

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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