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‘Decoy’ protein mitigates lung damage, death induced by aggressive SARS-CoV-2 variants

A drug treatment that acts as a decoy against SARS-CoV-2 was highly effective at preventing death and lung damage in humanized animal models of severe COVID-19 disease, according to a Nature Chemical Biology study from researchers at the University of Illinois Chicago.

19 Jan 2022

Research finds quick recovery of heart function in children with COVID-19-related MIS-C

Heart function recovery returned within three months in children who developed COVID-19-related multisystem inflammatory syndrome (MIS-C), according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

19 Jan 2022

Researchers investigate whether influenza impacted the epidemiological dynamics of SARS-CoV-2

Researchers wanted to test the co-infection and induced infectivity hypothesis that has been unexplored territory to date.

19 Jan 2022

Partial bone marrow transplant can dramatically improve survival of mice with cystic fibrosis

Scientists at La Jolla Institute for Immunology have found they can dramatically improve survival of mice with cystic fibrosis through a partial bone marrow transplant.

18 Jan 2022

Direct effect of SARS-CoV-2 on the kidney

Researchers infected human-induced pluripotent-stem-cell (iPSC)-derived kidney organoids with SARS-CoV-2 to study the virus's direct effect on the kidney.

18 Jan 2022

An alternative mouse model of SARS-CoV-2 infection

Recently, a study has shown the possibility of repurposing hACE2 transgenic mice, primarily raised to study SARS-CoV, to support SARS-CoV-2 infection and pathogenesis.

17 Jan 2022

Study suggests myeloid cell dysregulation is a driver of COVID-19 severity

Researchers determine the driving factors for disease severity and death due to COVID-19.

17 Jan 2022

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

A new study focused on the pathomorphological and virological characterization of SARS-CoV-2 in naturally infected, wild Indian Leopard.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

New model to identify biological markers in patients with COVID-19 and other illnesses

Investigators who recently developed a mathematical model that indicated why treatment responses vary widely among individuals with COVID-19 have now used the model to identify biological markers related to these different responses.

17 Jan 2022

Even mild SARS-CoV-2 respiratory-only infection can cause long-term neurologic damage

A new bioRxiv* preprint study led by Michelle Monje of Stanford University in California finds that a mild COVID-19 infection can produce long-term neurological damage. Persistent cognitive complications are one of many symptoms of long COVID, and the latest results suggest the severity of COVID-19 induced brain fog is similar to cancer’s “chemobrain.”

16 Jan 2022

Study reveals factors responsible for increased risk of aerosol transmission for SARS-CoV-2 Delta and Omicron

A new study describes the expected distribution of viral emission of COVID-19 by an infected population of people who were either silent, speaking softly, or loudly, to determine factors influencing risks of viral transmission.

14 Jan 2022

Virus-like particles as delivery vehicles for gene-editing

Scientists deliver gene-editing proteins through the use of engineered virus-like particles, which mediated efficient base editing both in vitro and in vivo.

13 Jan 2022

Plasma SARS-CoV-2 viral RNA as a valuable biomarker for SARS-CoV-2 infection in the lungs

Researchers recently evaluated respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA (vRNA) levels in longitudinal samples collected simultaneously from mechanically ventilated coronavirus disease 2019 (COVID-19) patients and analyzed their connections and relationships with clinical outcomes.

13 Jan 2022

Lungs News and Research

‘Decoy’ protein mitigates lung damage, death induced by aggressive SARS-CoV-2 variants

Research finds quick recovery of heart function in children with COVID-19-related MIS-C

Researchers investigate whether influenza impacted the epidemiological dynamics of SARS-CoV-2

Partial bone marrow transplant can dramatically improve survival of mice with cystic fibrosis

Direct effect of SARS-CoV-2 on the kidney

An alternative mouse model of SARS-CoV-2 infection

Study suggests myeloid cell dysregulation is a driver of COVID-19 severity

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

New model to identify biological markers in patients with COVID-19 and other illnesses

Even mild SARS-CoV-2 respiratory-only infection can cause long-term neurologic damage

Study reveals factors responsible for increased risk of aerosol transmission for SARS-CoV-2 Delta and Omicron

Virus-like particles as delivery vehicles for gene-editing

Plasma SARS-CoV-2 viral RNA as a valuable biomarker for SARS-CoV-2 infection in the lungs

Microbial characteristics of COVID-19

Role of leptin in immune modulation and pathophysiology of COVID-19

Hemp compounds show ability to prevent the entry of SARS-CoV-2 into cells

Manipulating voltage patterns in tumor cells reduces breast cancer metastasis in animal models

New study identifies ways to detect COPD in low- and middle-income countries

COVID-19 symptoms found to vary in different immune contexts

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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