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Researchers report development of a self-assembled trimeric RBD subunit vaccine able to prevent SARS-CoV-2 infection

The present study reported the development of a new self-assembled trimeric RBD subunit vaccine that could effectively prevent infection from SARS-CoV-2 variants, including the currently dominantly circulating Omicron variant.

21 Sep 2022

Study finds telomeres can set damage thresholds for cancer cells above which they cannot continue to divide

A recent study hypothesized that ALT might compromise telomere integrity if not restricted appropriately.

21 Sep 2022

Study reveals increased immunity evasion by Omicron BA.2.75.2

In a recent study posted to the bioRxiv* preprint server, researchers from ETH Zurich, Imperial College London, and Karolinska Institutet identified increased resistance to antibody-mediated neutralization by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineage BA.2.75.2.

21 Sep 2022

Green tea molecule can break up protein tangles in the brain that cause Alzheimer’s

Scientists at UCLA have used a molecule found in green tea to identify additional molecules that could break up protein tangles in the brain thought to cause Alzheimer's and similar diseases.

20 Sep 2022

Neutralizing antibody responses, breakthrough SARS-CoV-2 infections, and symptoms after booster BNT162b2 COVID-19 vaccinations

A new study evaluated neutralizing antibody (nAb) responses against the SARS-CoV-2 Omicron variant induced by booster vaccination with Pfizer-BioNTech’s BNT162b2 messenger ribonucleic acid vaccine.

20 Sep 2022

The potential of nanobody engineering in the development of SARS-CoV-2 antivirals and diagnostic tools

Researchers investigated nanobody engineering to develop antivirals and diagnostic tools against SARS-CoV-2.

20 Sep 2022

In Denmark, Omicron reinfections reveal ineffective post-COVID-19 immunity

In a recent study posted to the medRxiv* preprint server, researchers investigated variant-wise SARS-CoV-2 reinfection cases in Denmark.

20 Sep 2022

Molecular engineered low-cost highly effective RBD-based COVID vaccine

In a recent study posted to the bioRxiv* preprint server, an international team of researchers developed a second-generation severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor binding domain (RBD) antigen (RBD-J6) by molecular engineering with two additional amino acid (aa) substitutions (S383D and L518D mutations) in a hydrophobic cryptic RBD core epitope to enhance stability and expression against SARS-CoV-2 variants of concern (VOCs).

19 Sep 2022

Highly sensitive mask can detect respiratory viruses in the air within 10 minutes

Scientists have created a face mask that can detect common respiratory viruses, including influenza and the coronavirus, in the air in droplets or aerosols.

19 Sep 2022

Comparative hospitalization and mortality risk in the US population during the Omicron and Delta periods

Researchers compared in-hospital mortality across COVID-19 pandemic periods.

19 Sep 2022

Study develops single-use microneedle patch tattoos with wide-ranging application potential

Researchers developed a rapid, sterile, and painless method of tattooing using single-use microneedle tattoo patches, which can be used for cosmetic and veterinary applications and storing medical information.

19 Sep 2022

Vaccines used to prevent monkeypox

A new review published in The Lancet Infectious Diseases aimed to describe the efficacy of vaccinia virus-based smallpox vaccines against the current monkeypox outbreak.

18 Sep 2022

Needle-free jet injection of novel COVID-19 DNA vaccine shows promise in animal model

In a recent study posted to the bioRxiv* server, researchers at the United States Army Medical Research Institute of Infectious Diseases evaluated the immunogenicity of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) deoxyribonucleic acid (DNA) vaccine, nCOV-S(JET), in rhesus macaques

18 Sep 2022

Research examines the roles of cytokines during SARS-CoV-2 infection in rhesus macaques

In a recent study posted to the bioRxiv* preprint server, researchers in the United States assessed the role of two cytokines, interferon-gamma (IFN-γ) and interleukin-10 (IL-10), in regulating immune cell responses and inflammation early during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in rhesus macaques.

18 Sep 2022

An improved COVID-19 vaccine shows promise against Omicron in experimental models

In a recent study published in the journal Science Translational Medicine, researchers in the United States designed a bivalent coronavirus disease 2019 (COVID-19) vaccine on the messenger ribonucleic acid (mRNA) platform.

18 Sep 2022

Mortality risk higher among children with primary immunodeficiency diseases infected with SARS-CoV-2

Children with certain immunodeficiency diseases carry mutations in genes that regulate the body's immune system against viral infections and they have a higher mortality rate due to COVID-19.

16 Sep 2022

Study shows differences in treatment outcomes for Black vs. white women with hormone receptor-positive breast cancer

A study led by City of Hope, one of the largest cancer research and treatment organizations in the United States, found that Black women with Stage 1 or 2 breast cancer were almost three times more likely than white women to have tumor shrinkage from hormone therapy delivered prior to surgery, yet Black women were more likely than their white counterparts to have worse outcomes when this type of endocrine therapy before surgery was used at a later stage of disease.

16 Sep 2022

SARS-CoV-2 N escape mutations do not affect rapid antigen testing

A new study maps the escape mutations found in various strains of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could cause them to escape neutralization by antibodies or detection by rapid antigen tests that rely on antibody binding for a positive result.

16 Sep 2022

SARS-CoV-2 infection and vaccination results in highest and longest-lasting antibody response

A prospective seroprevalence study in the Catalan population underlines the need to get vaccinated despite having been infected and confirms that hybrid immunity (vaccination plus infection) is more robust and long-lasting.

16 Sep 2022

Study evaluates how rapid tests will perform when challenged with future SARS-CoV-2 variants

The availability of rapid antigen tests has significantly advanced efforts to contain the spread of COVID-19, but every new variant of concern raises questions about whether diagnostic tests will still be effective.

15 Sep 2022

Antibodies News and Research

Researchers report development of a self-assembled trimeric RBD subunit vaccine able to prevent SARS-CoV-2 infection

Study finds telomeres can set damage thresholds for cancer cells above which they cannot continue to divide

Study reveals increased immunity evasion by Omicron BA.2.75.2

Green tea molecule can break up protein tangles in the brain that cause Alzheimer’s

Neutralizing antibody responses, breakthrough SARS-CoV-2 infections, and symptoms after booster BNT162b2 COVID-19 vaccinations

The potential of nanobody engineering in the development of SARS-CoV-2 antivirals and diagnostic tools

In Denmark, Omicron reinfections reveal ineffective post-COVID-19 immunity

Molecular engineered low-cost highly effective RBD-based COVID vaccine

Highly sensitive mask can detect respiratory viruses in the air within 10 minutes

Comparative hospitalization and mortality risk in the US population during the Omicron and Delta periods

Study develops single-use microneedle patch tattoos with wide-ranging application potential

Vaccines used to prevent monkeypox

Needle-free jet injection of novel COVID-19 DNA vaccine shows promise in animal model

Research examines the roles of cytokines during SARS-CoV-2 infection in rhesus macaques

An improved COVID-19 vaccine shows promise against Omicron in experimental models

Mortality risk higher among children with primary immunodeficiency diseases infected with SARS-CoV-2

Study shows differences in treatment outcomes for Black vs. white women with hormone receptor-positive breast cancer

SARS-CoV-2 N escape mutations do not affect rapid antigen testing

SARS-CoV-2 infection and vaccination results in highest and longest-lasting antibody response

Study evaluates how rapid tests will perform when challenged with future SARS-CoV-2 variants

How to make hybridoma-based antibody discovery more efficient eBook

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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