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Cat antiviral that inhibits SARS-CoV-2 fast-tracked for human clinical trials

Now, a team of researchers at the University of Alberta in Canada has identified viral inhibitors that they claim are potential candidates as a treatment for COVID-19. The team is set to launch clinical trials of the drug that is used as a treatment for a type of coronavirus in cats.

31 Aug 2020

New lipid derivatives of Remdesivir have higher anti-coronavirus activity

In a fascinating new preprint paper published on bioRxiv* in August 2020, the researchers report “the synthesis and antiviral evaluation of three novel lipophilic prodrugs of RVn-monophosphate that are substantially more active than Remdesivir in cells infected with SARS-CoV-2.” These could be of immense use in treating COVID-19 patients early and helping to end transmission.

30 Aug 2020

Scientists describe known approaches for treatment of SARS-CoV-2 infection

Researchers from Sechenov University together with Russian and Iranian colleagues described currently known approaches to the treatment of SARS-CoV-2 infection.

29 Aug 2020

Universal health coverage study reveals that the world likely to fall short of WHO goal

A new study projects that 3.1 billion people will still lack effective health service coverage in 2023, with 968 million of those residing in South Asia.

28 Aug 2020

Researchers develop advanced imaging technique to visualize effects of valencies on B cell responses

Designing a vaccine starts with finding the right ingredients. Every infectious agent has molecules, called antigens, that the immune system could potentially recognize and attack. So scientists must carefully consider which antigens should go into a vaccine.

28 Aug 2020

Study shows how genetics could improve safety and efficacy of drugs for COVID-19 treatment

Over the past few months, a number of drugs have been under investigation to treat COVID-19 without well-established safety or data to support these claims.

28 Aug 2020

Study shows furin cleavage site is crucial for SARS-CoV-2 replication

In a recent bioRxiv* preprint paper, researchers from the United States demonstrate the pivotal role the furin cleavage site insertion in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein plays in viral replication and pathogenesis – highlighting, in turn, the need for mutation monitoring when developing therapeutics and vaccines.

27 Aug 2020

Patients from BAME communities are underrepresented in HIV research

People with HIV from BAME communities, women and heterosexual men are underrepresented in HIV studies – according to new research from the University of East Anglia and Western Sydney University.

27 Aug 2020

Heat Biologics SARS-CoV-2 vaccine generates potent T cell response in pre-clinical trial

The COVID-19 pandemic is still creating economic and health-related impact over the world. A new study published on the preprint server bioRxiv in August 2020 shows that a gp96-Ig-secreting vaccine candidate based on the expression of full-length spike protein generates a potent T cell response.

26 Aug 2020

Researchers identify how promising therapy may work to improve adverse effects of NAFLD

A team led by researchers at Massachusetts General Hospital (MGH) has taken an important step forward in the goal of developing a potential treatment for non-alcoholic fatty liver disease (NAFLD), the most common form of chronic liver disease.

26 Aug 2020

Racial segregation contributes to disparities in COVID-19 and HIV diagnoses

Across the U.S., COVID-19 and HIV diagnoses are lowest in primarily white counties.

26 Aug 2020

Feeling anxious and depressed? You’re right at home in California.

It's official, California: COVID-19 has left us sick with worry and increasingly despondent. And our youngest adults — ages 18 to 29 — are feeling it worst.

26 Aug 2020

LA hospital seeks vaccine trial participants among its own high-risk patients

The patients at Dr. Eric Daar's hospital are at high risk for serious illness from COVID-19, and he's determined to make sure they're part of the effort to fight the disease.

26 Aug 2020

UC Berkeley demographers calculate the consequences of U.S. lives lost to COVID-19

With over 170,000 COVID-19 deaths to date, and 1,000 more each day, America's life expectancy may appear to be plummeting.

25 Aug 2020

Advances in Virus Epigenetics

Growing evidence shows viruses exploit epigenetic processes to control their life cycles but epigentic regulation of viral infections is not fully understood.

From Chromatrap® - Porvair Sciences Ltd 25 Aug 2020

Researchers identify mechanisms leading to immune 'exhaustion' in severe viral infections

Melbourne researchers have identified mechanisms leading to the functional deterioration of the immune system in response to severe viral infections, such as HIV or COVID-19.

24 Aug 2020

Drug resistance may be reversed using hydrogen sulphide

Antibiotic resistance in some kinds of bacteria may be reversed using hydrogen sulphide (H2S), according to a new study.

24 Aug 2020

Florida’s cautionary tale: How gutting and muzzling public health fueled COVID fire

On a sweltering July morning, Rose Wilson struggled to breathe as she sat in her bed, the light from her computer illuminating her face and the oxygen tubes in her nose.

24 Aug 2020

Nasal vaccine effective in preventing COVID-19 infection in mice

Scientists at Washington University School of Medicine in St. Louis have developed a vaccine that targets the SARS-CoV-2 virus, can be given in one dose via the nose and is effective in preventing infection in mice susceptible to the novel coronavirus.

21 Aug 2020

Researchers find clues to successful immune response in the T cells of COVID-19 patients

When news about a novel coronavirus switched from a chronicle of its progress in China to headlines about a worldwide COVID-19 pandemic, Gladstone Institutes scientist Nadia Roan, PhD, was in the midst of publishing several papers on T cells and their role in HIV spread and long-lasting infections.

21 Aug 2020

HIV News and Research

Cat antiviral that inhibits SARS-CoV-2 fast-tracked for human clinical trials

New lipid derivatives of Remdesivir have higher anti-coronavirus activity

Scientists describe known approaches for treatment of SARS-CoV-2 infection

Universal health coverage study reveals that the world likely to fall short of WHO goal

Researchers develop advanced imaging technique to visualize effects of valencies on B cell responses

Study shows how genetics could improve safety and efficacy of drugs for COVID-19 treatment

Study shows furin cleavage site is crucial for SARS-CoV-2 replication

Patients from BAME communities are underrepresented in HIV research

Heat Biologics SARS-CoV-2 vaccine generates potent T cell response in pre-clinical trial

Researchers identify how promising therapy may work to improve adverse effects of NAFLD

Racial segregation contributes to disparities in COVID-19 and HIV diagnoses

Feeling anxious and depressed? You’re right at home in California.

LA hospital seeks vaccine trial participants among its own high-risk patients

UC Berkeley demographers calculate the consequences of U.S. lives lost to COVID-19

Advances in Virus Epigenetics

Researchers identify mechanisms leading to immune 'exhaustion' in severe viral infections

Drug resistance may be reversed using hydrogen sulphide

Florida’s cautionary tale: How gutting and muzzling public health fueled COVID fire

Nasal vaccine effective in preventing COVID-19 infection in mice

Researchers find clues to successful immune response in the T cells of COVID-19 patients

Exploring the G:Box and for high-quality imaging

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How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

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