Biochemistry

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Study reveals new opportunities for using small molecule drugs to target KRAS mutants

Research published today in Nature Chemical Biology reveals new opportunities for using small molecule drugs to target KRAS, the most commonly mutated protein in cancer.

23 Mar 2022

Groundbreaking chemical technique could reveal new treatments for cancer and other diseases

Leicester researchers have described application of a pioneering chemical technique which could unlock ground-breaking new treatments for cancer and other diseases.

23 Mar 2022

New approach could lead to quicker generation of effective, personalized cancer vaccines

Scientists have created a pipeline for identifying, prioritizing and evaluating potential tumor antigens for the fast generation of cancer vaccines, according to a report published today in eLife.

22 Mar 2022

Fermented soybean waste could help mitigate effects of diet-induced obesity

An international team of scientists from Nanyang Technological University, Singapore (NTU Singapore) and Waseda University in Japan have found that fermented soybean waste, or okara, could improve fat metabolism and mitigate effects of diet-induced obesity.

22 Mar 2022

Researchers identify a protein that protects against breast cancer growth

Researchers at Karolinska Institutet in Sweden have identified a protein that protects against breast tumor growth and that can be linked to a better prognosis in breast cancer patients.

22 Mar 2022

Research reveals enzyme-driven process that activates anti-cancer molecule

Years of toil in the laboratory have revealed how a marine bacterium makes a potent anti-cancer molecule.

21 Mar 2022

Waste coffee grounds may help detect minute levels of neurotransmitters

There's nothing like a steaming cup of joe to give your morning a quick boost. Now, there's yet another reason to love the beverage.

20 Mar 2022

Higher doses of antibiotics are needed to eliminate infection in a polymicrobial environment

A study has found that much higher doses of antibiotics are needed to eliminate a bacterial infection of the airways when other microbes are present.

19 Mar 2022

Inhalable ‘aerogel’ induces immune response against COVID-19 in the lungs of mice

An inhalable 'aerogel' loaded with DNA that encodes for the SARS-CoV-2 spike protein successfully induces an immune response against COVID-19 in the lungs of mice, according to new research conducted at Penn State.

16 Mar 2022

Sneaking large drug-carrying biological molecules into cells using a novel drug delivery system

Scientists from Nanyang Technological University, Singapore have developed a novel method of delivering drugs into human cells using large biological molecules, by first encasing them in a protein-based microdroplet.

16 Mar 2022

Previously unknown bacterial enzyme makes new type of polysaccharide

Strings of sugars called polysaccharides are the most abundant biopolymers on Earth. Because of their versatile and environmentally friendly properties, these molecules could eventually replace some plastics.

16 Mar 2022

Researchers illuminate the link between autophagy and the body's metabolic response to fasting

The coming of spring harkens spring cleaning; a time to de-clutter your home and discard things that are no longer needed. In the body, a cellular process called autophagy occurs regularly to "de-clutter" our cells.

15 Mar 2022

Modifying red blood cells to create a promising new vehicle for vaccine delivery

Physicists, chemists and immunologists at McMaster University have teamed up to modify red blood cells to transport viral agents which can safely trigger the immune system to protect the body against SARS-CoV-2, creating a promising new vehicle for vaccine delivery.

11 Mar 2022

New analysis method to identify interacting proteins in a protein degrader-dependent manner

Protein degraders, which induce the protein degradation of target proteins, are expected to be the "next-generation drugs" because they can remove disease-related proteins from cells.

8 Mar 2022

UH researchers receive grant for developing new imaging technique to peer into ribosomes

Two University of Houston researchers are developing a type of spectroscopy to help understand how ribosomes make proteins deep within cells, the discovery of which could potentially guide drug design to treat cancers and viral infections.

8 Mar 2022

A promising approach for COVID-19 prophylaxis

SARS-CoV-2 viruses can hide from recognition by the immune system. However, the antiviral immune receptor RIG-I can be stimulated, which improves protection against lethal SARS-CoV-2 infections.

8 Mar 2022

GlyNAC supplementation can increase lifespan and improve multiple age-associated defects

Many people aspire to live longer, healthier lives. A researcher at Baylor College of Medicine, Dr. Rajagopal Sekhar, associate professor of medicine in the section of endocrinology, diabetes and metabolism, has been studying aging for the past 20 years to better understand its biological underpinnings and develop nutritional strategies to promote healthy aging.

7 Mar 2022

Manipulating carotenoids can improve plant growth, stress tolerance and increase yield

Manipulating the content of carotenoids, such as ß-carotene, has been found to improve plant growth and increase yield and tolerance to abiotic stresses such as drought and salinity.

7 Mar 2022

CABI scientists reveal the safety of a classical biological control agent against Drosophila suzukii

CABI scientists have led new research which highlights the safety of a classical biological control agent against the devastating invasive fruit fly Drosophila suzukii which attacks over 150 wild and cultivated fruits, including cherries, blueberries and strawberries, as well as the fruits of ornamental plants.

7 Mar 2022

Study may pave the way for better multiple sclerosis drugs

Investigators from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have discovered how a drug for multiple sclerosis interacts with its targets, a finding that may pave the way for better treatments.

4 Mar 2022

Biochemistry

Study reveals new opportunities for using small molecule drugs to target KRAS mutants

Groundbreaking chemical technique could reveal new treatments for cancer and other diseases

New approach could lead to quicker generation of effective, personalized cancer vaccines

Fermented soybean waste could help mitigate effects of diet-induced obesity

Researchers identify a protein that protects against breast cancer growth

Research reveals enzyme-driven process that activates anti-cancer molecule

Waste coffee grounds may help detect minute levels of neurotransmitters

Higher doses of antibiotics are needed to eliminate infection in a polymicrobial environment

Inhalable ‘aerogel’ induces immune response against COVID-19 in the lungs of mice

Sneaking large drug-carrying biological molecules into cells using a novel drug delivery system

Previously unknown bacterial enzyme makes new type of polysaccharide

Researchers illuminate the link between autophagy and the body's metabolic response to fasting

Modifying red blood cells to create a promising new vehicle for vaccine delivery

New analysis method to identify interacting proteins in a protein degrader-dependent manner

UH researchers receive grant for developing new imaging technique to peer into ribosomes

A promising approach for COVID-19 prophylaxis

GlyNAC supplementation can increase lifespan and improve multiple age-associated defects

Manipulating carotenoids can improve plant growth, stress tolerance and increase yield

CABI scientists reveal the safety of a classical biological control agent against Drosophila suzukii

Study may pave the way for better multiple sclerosis drugs

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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