Biochemistry

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Combing Raman spectroscopy and chemometrics for estimating post-mortem interval in human remains

In the field of forensic analysis there is a significant demand for objectively determining the post-mortem interval (PMI) when human skeletal remains are discovered.

29 Jan 2022

Study provides atomistic level insight into target residence time of small molecule kinase inhibitors

When a drug molecule binds to its target protein, it stays bound for some time before eventually unbinding the target. The actual time how long a drug molecule resides bound to its target varies among compounds.

29 Jan 2022

Origins of West African dishes with leafy vegetables date back to 3,500 years

Over 450 prehistoric pots were examined, 66 of them contained traces of lipids, that is, substances insoluble in water.

28 Jan 2022

Hyaluronic acid acts as food to pancreatic cancer cells, study shows

Hyaluronic acid, or HA, is a known presence in pancreatic tumors, but a new study from researchers at the University of Michigan Health Rogel Cancer Center shows that hyaluronic acid also acts as food to the cancer cells.

28 Jan 2022

Nutritional components hold promise for improving the health and well-being of adults

Emerging research indicates that nutritional components that target specific mechanisms associated with age-associated cellular decline (AACD) hold promise for improving the health and well-being of adults.

25 Jan 2022

Peptide-enhanced antibody therapy may help treat breast cancer metastasis to bone

A moderate amount of a peptide-enhanced, biological cancer drug goes a long way in treating breast cancers that metastasize to the bone.

24 Jan 2022

Novel compound found in mussels helps increase the durability of dental fillings

Leading researchers from the Faculty of Dentistry, the University of Hong Kong, Wuhan University, and the Peking University Shenzhen Hospital have found that a compound found in mussels helps increase the durability of a dental filling.

22 Jan 2022

Nano-bubbles containing ACE2 protein can block infection from broad strains of SARS-CoV-2

Scientists at Northwestern Medicine and The University of Texas MD Anderson Cancer Center have identified natural nano-bubbles containing the ACE2 protein (evACE2) in the blood of COVID-19 patients and discovered these nano-sized particles can block infection from broad strains of SARS-CoV-2 virus in preclinical studies.

21 Jan 2022

Natural extracellular vesicles containing ACE2 protein could fight new SARS-CoV-2 variants

Scientists at The University of Texas MD Anderson Cancer Center and Northwestern Medicine have identified natural extracellular vesicles containing the ACE2 protein (evACE2) in the blood of COVID-19 patients that can block infection from broad strains of SARS-CoV-2 virus in preclinical studies. The study was published today in Nature Communications.

20 Jan 2022

Investigational cancer drug mimics the metabolic and therapeutic effects of fasting, mice study shows

An investigational cancer drug that starves tumors of their energy supply also shows evidence of improving whole body metabolism, according to a new study in mice from Washington University School of Medicine in St. Louis.

19 Jan 2022

‘Decoy’ protein mitigates lung damage, death induced by aggressive SARS-CoV-2 variants

A drug treatment that acts as a decoy against SARS-CoV-2 was highly effective at preventing death and lung damage in humanized animal models of severe COVID-19 disease, according to a Nature Chemical Biology study from researchers at the University of Illinois Chicago.

19 Jan 2022

Scientific review highlights the impact of coffee on digestive organs

A new scientific review, published in Nutrients, highlights coffee's effects on digestion and the gut, and its impact on organs involved in digestion.

19 Jan 2022

Evaporators assist academic drug discovery

BioChromato Inc reports how the renowned Chemistry Research Laboratories (CRL) at Oxford University (UK) are using several Smart Evaporator C1 units to support their drug discovery activities in therapeutic areas including oncology and regenerative medicine.

From BioChromato Inc. 19 Jan 2022

Blocking an enzyme activity inside fat cells can reduce obesity in mice

Blocking the activity of an enzyme inside fat cells can decrease obesity and related health disorders in mice, according to new research led by the University of Michigan Life Sciences Institute.

17 Jan 2022

Researchers engineer enucleated cells to deliver therapeutics precisely to diseased tissues

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health report successfully removing the nucleus out of a type of ubiquitous cell, known as enucleation, then using the genetically engineered cell as a unique cargo-carrier to deliver therapeutics precisely to diseased tissues.

17 Jan 2022

UMass Amherst professor receives $2 million NIH MIRA grant for trailblazing research

Jianhan Chen, a University of Massachusetts Amherst chemistry and biochemistry and molecular biology professor, has received a five-year, $2 million National Institutes of Health (NIH) grant to support research in his computational biophysics lab aimed at better understanding the role of intrinsically disordered proteins (IDPs) in biology and human disease.

16 Jan 2022

Biochemistry

Combing Raman spectroscopy and chemometrics for estimating post-mortem interval in human remains

Study provides atomistic level insight into target residence time of small molecule kinase inhibitors

Origins of West African dishes with leafy vegetables date back to 3,500 years

Hyaluronic acid acts as food to pancreatic cancer cells, study shows

Nutritional components hold promise for improving the health and well-being of adults

Peptide-enhanced antibody therapy may help treat breast cancer metastasis to bone

Novel compound found in mussels helps increase the durability of dental fillings

Nano-bubbles containing ACE2 protein can block infection from broad strains of SARS-CoV-2

Natural extracellular vesicles containing ACE2 protein could fight new SARS-CoV-2 variants

Investigational cancer drug mimics the metabolic and therapeutic effects of fasting, mice study shows

‘Decoy’ protein mitigates lung damage, death induced by aggressive SARS-CoV-2 variants

Scientific review highlights the impact of coffee on digestive organs

Evaporators assist academic drug discovery

Blocking an enzyme activity inside fat cells can reduce obesity in mice

Researchers engineer enucleated cells to deliver therapeutics precisely to diseased tissues

UMass Amherst professor receives $2 million NIH MIRA grant for trailblazing research

Faster and more affordable method for detecting adulteration of meat products

Novel insights about dopamine can help find better drugs for Parkinson's patients

Food science experts characterize the properties of protein in several insect powders

AI-driven solution predicts RNA and DNA binding sites to accelerate rational drug discovery

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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