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Potential remaining COVID-19 burden in European countries

The researchers suggest governments should implement public health policies and non-pharmaceutical efforts to encourage vaccine-induced immunity.

12 Nov 2021

SARS-CoV-2 self-amplifying mRNA vaccine demonstrates cellular and humoral immune responses

Researchers from the US recently reported the preclinical development of a self-amplifying mRNA (SAM) vaccine that encodes a prefusion-stabilized SARS-CoV-2 spike glycoprotein.

12 Nov 2021

Xanthohumol as a potent pan-inhibitor for various coronaviruses

Researchers from China reported the results of their study aimed at finding an effective Mpro inhibitor since Mpro is the best drug target to fight SARS-CoV-2 infection.

12 Nov 2021

Immune responses with and without previous SARS-CoV-2 infection following single BNT162b2 vaccine dose

The Protective Immunity from T-cells to COVID-19 in Healthcare workers (PITCH) is a prospective, cohort, multi-center study enclosed within the SIREN study designed to assess the effectiveness of the BNT162b2 vaccine in healthcare workers.

12 Nov 2021

Impact of mutations on binding affinity of SARS-CoV-2 variants with ACE2 and existing antibodies

Researchers explained their analysis of the mechanisms that trigger the docking of SARS-CoV-2 variants to ACE2 and the antibodies, referred to as protein-protein docking.

12 Nov 2021

How safe is it to travel on public transport amid COVID-19?

The authors extended this research by proposing a time-varying weighted Public Transportation Encounter Network that modeled the COVID-19 infectious process observed on public transport.

12 Nov 2021

Rare disease diagnosis by 100,000 genomes pilot

A team of researchers conducted a pilot study that enrolled families and undertook detailed clinical phenotyping of the proband to evaluate the effect of the whole genome sequencing approach on a genetic diagnosis of rare conditions by the NHS in the UK.

12 Nov 2021

INTEGRA’s VOYAGER helps HIV researchers get more results in significantly less time

INTEGRA’s VOYAGER adjustable tip spacing pipette is supporting crucial experimental work in longitudinal HIV studies.

From INTEGRA Biosciences 12 Nov 2021

Study investigates the degree of Covid-19 vaccination protection in dialysis patients

Researchers led by the Marien Hospital Herne, a Ruhr-Universität Bochum clinic, have investigated the extent to which mRNA vaccines protect dialysis patients from infection with variants of concerns of Sars-Cov-2.

12 Nov 2021

Study may pave the way for a more personalized approach to COVID-19 diagnosis and treatment

Using some of the most advanced molecular sequencing tools available to evaluate COVID-19 rapid autopsy tissues, researchers have identified four major regulatory pathways, specific molecular effectors behind COVID-19 symptoms, and differences that drive diverging clinical courses among individual patients.

11 Nov 2021

Research finds greater mortality risk among rural COVID patients in ICUs than urban counterparts

The earliest wave of COVID-19 spared much of rural America, striking people who live in urban areas with far more frequency. The latest surge was different, however. Nonmetropolitan COVID cases outpaced metropolitan ones. So did overall COVID mortality rates.

11 Nov 2021

Analysis of immunodeficient patients granted REGEN-COV under compassionate use COVID-19 program

A team of scientists describe the safety and response to REGEN-COV® for COVID-19 patients with immunodeficiency-associated antibody disorders.

11 Nov 2021

Vaccinated patients hospitalized with COVID-19 in Norway spend fewer days in the hospital

A recent study looks at how mRNA vaccination affects hospitalization and ICU admission in COVID-19 breakthrough infections.

11 Nov 2021

Study shows 90.7% efficacy for the BNT162b2 COVID vaccine in 5-11 year-olds

A new study evaluates the safety, immunogenicity, and efficacy of the BNT162b2 in children who were 5 to 11 years of age.

11 Nov 2021

RT-LAMP coupled solid-state nanopores for SARS-CoV-2 detection

Researchers discuss a highly sensitive, specific, and rapid SARS-CoV-2 detection platform by coupling the RT-LAMP with glass nanopore sensors.

11 Nov 2021

Long-term effectiveness of Pfizer/BioNTech two-dose regimen mRNA vaccine

A group of scientists from Israel sought to evaluate the long-term effectiveness of the BioNTech/Pfizer mRNA BNT162b2 vaccine.

11 Nov 2021

Flu season emerging against the backdrop of COVID-19 pandemic

For the second straight year, flu season is emerging against the backdrop of the COVID-19 pandemic. While the number of flu cases was relatively low last year, experts at Johns Hopkins Medicine say that this year, it could be much higher.

11 Nov 2021

University of Oxford begins Phase I trial to test Ebola vaccine

The University of Oxford have begun recruiting for a Phase I trial to test an Ebola vaccine in human volunteers - with the first vaccinations taking place today (Thursday, 11 November).

11 Nov 2021

Long-lasting anti-spike and anti-membrane antibodies can differentiate between COVID-19 infection and vaccination

Researchers have been investigating which other proteins remain prevalent long enough for tests against them to be worthwhile.

11 Nov 2021

New Delta sublineage shows no additional resistance to neutralization

Researchers are attempting to determine the ability of this new sublineage to avoid neutralization by antibodies elicited from vaccination.

11 Nov 2021

Disease/Infection News

Potential remaining COVID-19 burden in European countries

SARS-CoV-2 self-amplifying mRNA vaccine demonstrates cellular and humoral immune responses

Xanthohumol as a potent pan-inhibitor for various coronaviruses

Immune responses with and without previous SARS-CoV-2 infection following single BNT162b2 vaccine dose

Impact of mutations on binding affinity of SARS-CoV-2 variants with ACE2 and existing antibodies

How safe is it to travel on public transport amid COVID-19?

Rare disease diagnosis by 100,000 genomes pilot

INTEGRA’s VOYAGER helps HIV researchers get more results in significantly less time

Study investigates the degree of Covid-19 vaccination protection in dialysis patients

Study may pave the way for a more personalized approach to COVID-19 diagnosis and treatment

Research finds greater mortality risk among rural COVID patients in ICUs than urban counterparts

Analysis of immunodeficient patients granted REGEN-COV under compassionate use COVID-19 program

Vaccinated patients hospitalized with COVID-19 in Norway spend fewer days in the hospital

Study shows 90.7% efficacy for the BNT162b2 COVID vaccine in 5-11 year-olds

RT-LAMP coupled solid-state nanopores for SARS-CoV-2 detection

Long-term effectiveness of Pfizer/BioNTech two-dose regimen mRNA vaccine

Flu season emerging against the backdrop of COVID-19 pandemic

University of Oxford begins Phase I trial to test Ebola vaccine

Long-lasting anti-spike and anti-membrane antibodies can differentiate between COVID-19 infection and vaccination

New Delta sublineage shows no additional resistance to neutralization

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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