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Early use of therapeutic anticoagulation does not improve survival of critically ill COVID-19 patients

Although abnormal blood clotting has been identified as one of the primary causes of death from COVID-19, early treatment in an intensive care unit (ICU) with therapeutic anticoagulation (anti-clotting) for adults who are critically ill with COVID-19 does not appear to improve chances of survival, and could do more harm than good by increasing the risk for major bleeding, a multicenter research group cautions.

3 Feb 2021

Phase 1 clinical trial of novel HIV vaccine approach shows promising results

A phase 1 clinical trial testing a novel vaccine approach to prevent HIV has produced promising results, IAVI and Scripps Research announced today.

3 Feb 2021

Latest clinical trial supports UK’s decision to delay second COVID vaccine dose

Researchers in the UK, South Africa and Brazil have reported the latest efficacy results from phase III trials of the Oxford–AstraZeneca vaccine currently being rolled out in the UK to protect against coronavirus disease 2019 (COVID-19).

3 Feb 2021

Viral load the main driver of SARS-CoV-2 transmission

A study conducted by researchers in the UK and Spain suggests that viral load is the main determinant of transmission risk in cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

3 Feb 2021

Experimental intranasal influenza vaccine produces durable immune response

An experimental single-dose, intranasal influenza vaccine was safe and produced a durable immune response when tested in a Phase 1 study published in the Journal of Clinical Investigation.

3 Feb 2021

Could rapid result low sensitivity SARS-CoV-2 tests improve pandemic quarantine strategies?

Researchers in the USA have re-examined current testing and quarantining regimens for SARS-CoV-2. They suggest that the RT-PCR method and 14-day isolation rule may not be the most effective approach in managing viral transmission.

3 Feb 2021

Researchers engineer "Nanotraps" that block SARS-CoV-2 infection

Researchers at Chicago University have developed an innovative new anti-SARS-CoV-2 therapy called “Nanotraps” – a family of nano-enabled virus-trapping particles – which have shown positive results in vitro, in vivo, and in human ex vivo trials.

3 Feb 2021

People with severe mental disorders have higher risk of death from COVID-19

People with severe mental disorders have a significantly increased risk of dying from COVID-19. This has been shown in a new study from Umeå University and Karolinska Institutet in Sweden.

3 Feb 2021

100 million covid shots in 100 days doesn’t get us back to normal

April 30 will mark the end of the first 100 days of President Joe Biden's tenure. That's a benchmark presidents often set for making good on high-priority campaign promises.

3 Feb 2021

Researchers survey repurposed drugs that inhibit SARS-CoV-2 replication in vitro

A new study by researchers at the University of Manchester, UK, reports on the compounds of interest that were identified as having potential for the treatment of COVID-19, from a library of almost 2,000 compounds from the APExBIO DiscoveryProbe library.

3 Feb 2021

Genomic study suggests SARS-CoV-2 clade 20C was imported into Japan from the US

A new study describes the outcome of such sequencing efforts in Japan as an important tool towards containing the spread of the infection.

3 Feb 2021

Long COVID-19 symptoms not associated with reduced cell-mediated immunity, finds study

A new preprint examines Long COVID-19, aiming to identify the underlying immunologic status in such patients.

3 Feb 2021

Oxysterol derivatives show powerful antiviral activity against SARS-CoV-2 in vitro

A new study describes the antiviral activity of oxysterols, or oxidized cholesterol derivatives, against SARS-CoV-2. These occur in nature, and are not only involved in lipid signaling pathways that modulate a host of processes within the body, including the immune response and lipid homeostasis.

3 Feb 2021

IONICON analyzers at the forefront of COVID-19 testing research

COVID-19 breath detection is studied around the globe using PTR-TOFMS.

From Ionicon Analytik Ges.m.b.H. 3 Feb 2021

Pregnant women had higher symptoms of depression, anxiety during COVID-19 pandemic

During the lockdown in the first wave of the COVID-19 pandemic in Spain, pregnant women had higher symptoms of depression and anxiety.

3 Feb 2021

Study finds higher pediatric SARS-CoV-2 burden than previously reported in the U.S.

In a new study, published on the pre-print server medRxiv*, researchers at Inova Children's Hospital and the George Mason University revealed that a much higher burden of SARS-CoV-2 infection was found in children than previously reported. This comes after the researchers assessed seropositivity among 1,038 children and adolescents.

3 Feb 2021

Researchers report trial results of rectal microbicides at HIV R4P Virtual Conference

Researchers seeking to develop on-demand and behaviorally congruent HIV prevention options for people who practice anal sex are reporting the results of three early phase clinical trials of rectal microbicides at this week's HIV Research for Prevention (HIV R4P) Virtual Conference.

3 Feb 2021

Disease/Infection News

Early use of therapeutic anticoagulation does not improve survival of critically ill COVID-19 patients

Phase 1 clinical trial of novel HIV vaccine approach shows promising results

Latest clinical trial supports UK’s decision to delay second COVID vaccine dose

Viral load the main driver of SARS-CoV-2 transmission

Experimental intranasal influenza vaccine produces durable immune response

Could rapid result low sensitivity SARS-CoV-2 tests improve pandemic quarantine strategies?

Researchers engineer "Nanotraps" that block SARS-CoV-2 infection

People with severe mental disorders have higher risk of death from COVID-19

100 million covid shots in 100 days doesn’t get us back to normal

Researchers survey repurposed drugs that inhibit SARS-CoV-2 replication in vitro

Genomic study suggests SARS-CoV-2 clade 20C was imported into Japan from the US

Long COVID-19 symptoms not associated with reduced cell-mediated immunity, finds study

Oxysterol derivatives show powerful antiviral activity against SARS-CoV-2 in vitro

IONICON analyzers at the forefront of COVID-19 testing research

Pregnant women had higher symptoms of depression, anxiety during COVID-19 pandemic

Study finds higher pediatric SARS-CoV-2 burden than previously reported in the U.S.

Researchers report trial results of rectal microbicides at HIV R4P Virtual Conference

Novel strategy redirects generic antibodies to SARS-CoV-2 spike proteins

New risk stratification models could assist COVID-19 management

Airborne Infection Rate index predicts timing of second wave of pandemic

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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