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Researchers receive £230,000 to develop world's first smart vaccine device

Researchers at Swansea University have received £230,000 to develop the world's first smart vaccine device that will both deliver the COVID-19 vaccine and measure its efficacy through monitoring the body's associated response.

6 Jan 2021

Study reveals top reasons for COVID-19 vaccine refusal

A survey of approximately 5,000 Americans suggests that 31.1 percent of the U.S. public does not intend to get the COVID-19 vaccine once it becomes available to them - and the likelihood of vaccine refusal is highest among Black Americans, women and conservatives.

6 Jan 2021

Smokers at increased risk of developing symptomatic COVID-19

Smoking is associated with an increased risk of COVID-19 symptoms and smokers are more likely to attend hospital than non-smokers, a study has found.

6 Jan 2021

NIAID set to conduct large monoclonal SARS-CoV-2 antibody clinical trial

A large clinical trial, known as the Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV-2), is set to take place, which aims to test monoclonal antibody efficacy and safety in people who have mild or moderate COVID-19.

6 Jan 2021

Vitamin D supplementation found to reduce COVID-19-related mortality, says study

Researchers have shown that prescribing vitamin D supplementation to COVID-19 patients seems to decrease the mortality rate, the severity of the disease, and serum levels of inflammatory markers.

6 Jan 2021

Evidence review: COVID-19 infections are generally 'mild' in children under five years

Babies and asymptomatic cases account for up to half of COVID-19 infections in the under-five age group, which has implications for vaccination programs, a new UNSW study has found.

6 Jan 2021

Disulfide-reducing agents demonstrate potential antiviral activity against SARS-CoV-2

Researchers recently demonstrated that chemical agents capable of reducing disulfide (S-S) bonds can be potentially used as antiviral drugs against SARS-CoV-2, the causative pathogen of COVID-19.

6 Jan 2021

Modified Vaccinia Ankara model vaccine prevents COVID-19 in transgenic mice study

A new study shows the effectiveness of a novel recombinant vaccinia virus that expresses modified SARS-CoV-2 spike antigen, in preventing the replication of the virus in the respiratory tract of transgenic mice, and to prevent lethal disease.

6 Jan 2021

Are SARS-CoV-2 antibodies associated with disease enhancement?

As SARS-CoV-2 continues to wreak its havoc, antibodies that neutralize the virus and protect against infection have become an important focus of research. However, there is a concern as to whether these antibodies can actually enhance the disease.

6 Jan 2021

Study examines prevalence and recovery in patients with varying degrees of COVID-19 severity

A reduced sense of smell, or olfactory dysfunction, is one of the most common symptoms of COVID-19. A recent study published the Journal of Internal Medicine has examined it prevalence and recovery in patients with varying degrees of severity of COVID-19.

6 Jan 2021

Researchers test the effects of growth molecules exuded by oral bacteria

The human body is filled with friendly bacteria. However, some of these microorganisms, such as Veillonella parvula, maybe too nice.

6 Jan 2021

Researchers claim SARS-CoV-2 B.1.1.7 variant likely to become globally dominant

The new variant of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) detected in England replicates more than two times faster than the earlier strains. This replication advantage promises to make it the dominant global variant very shortly. This finding comes from a startling preprint that appeared on the medRxiv* server in December 2020.

6 Jan 2021

New mathematical model proposes optimal treatment strategies for COVID-19

Getting control of COVID-19 will take more than widespread vaccination; it will also require a better understanding of why the disease causes no apparent symptoms in some people but leads to rapid multi-organ failure and death in others, as well as better insight into what treatments work best and for which patients.

5 Jan 2021

Glycyrrhizin in licorice root neutralizes SARS-CoV-2 in vitro by inhibiting the main protease Mpro

In a recent bioRxiv* preprint paper, researchers from Germany analyzed aqueous licorice root extract for its neutralizing activity against SARS-CoV-2 in vitro. They identified glycyrrhizin, the primary active ingredient in the root, and revealed the underlying mechanism of viral neutralization.

5 Jan 2021

One-third of COVID-19 survivors manifest neurological problems

In a longitudinal study recently published on the preprint server medRxiv*, Andrea Pilotto et al. find that one-third of COVID-19 infection survivors have long-term neurological manifestations after hospitalization.

5 Jan 2021

COVID-19 vaccine hesitancy in UK varies significantly between population subgroups

Researchers investigating attitudes towards vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among the UK population have found that, overall, most people were willing to accept a vaccine.

5 Jan 2021

UC-MSC infusions reduce risk of death, quicken recovery time in severe COVID-19 cases

Dr. Camilo Ricordi, director of the Diabetes Research Institute and Cell Transplant Center at the University of Miami Miller School of Medicine, and his team of international collaborators are reporting the results of a groundbreaking randomized controlled trial showing umbilical cord-derived mesenchymal stem cell (UC-MSC) infusions safely reduce risk of death and quicken time to recovery for the most severe COVID-19 patients.

5 Jan 2021

Disease/Infection News

Researchers receive £230,000 to develop world's first smart vaccine device

Study reveals top reasons for COVID-19 vaccine refusal

Smokers at increased risk of developing symptomatic COVID-19

NIAID set to conduct large monoclonal SARS-CoV-2 antibody clinical trial

Vitamin D supplementation found to reduce COVID-19-related mortality, says study

Evidence review: COVID-19 infections are generally 'mild' in children under five years

Disulfide-reducing agents demonstrate potential antiviral activity against SARS-CoV-2

Modified Vaccinia Ankara model vaccine prevents COVID-19 in transgenic mice study

Are SARS-CoV-2 antibodies associated with disease enhancement?

Study examines prevalence and recovery in patients with varying degrees of COVID-19 severity

Researchers test the effects of growth molecules exuded by oral bacteria

Researchers claim SARS-CoV-2 B.1.1.7 variant likely to become globally dominant

New mathematical model proposes optimal treatment strategies for COVID-19

Glycyrrhizin in licorice root neutralizes SARS-CoV-2 in vitro by inhibiting the main protease Mpro

One-third of COVID-19 survivors manifest neurological problems

COVID-19 vaccine hesitancy in UK varies significantly between population subgroups

UC-MSC infusions reduce risk of death, quicken recovery time in severe COVID-19 cases

Three teams at Binghamton University awarded grants to pursue COVID-19 research projects

COVID-19 vaccination in UK may not lead to relaxation of control measures

Cellid, IVI sign research service contract to evaluate immunogenicity of COVID-19 vaccine

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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