Disease/Infection News

RSS

Transgenic mouse model could recapitulate severe COVID-19 in humans

Researchers in the United States and Canada have described the potential for a transgenic mouse model to serve as an effective platform for the study of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and severe disease course in humans.

26 Nov 2020

COVID-19 may trigger recurrent Guillain–Barré Syndrome episodes, a case study shows

A team of researchers at the Robert Wood Johnson Medical School, Rutgers University, USA, have investigated a case wherein a man experienced recurrent episodes of Guillain–Barré Syndrome after being infected with SARS-CoV-2.

26 Nov 2020

SARS-CoV-2 immunity can sustain for at least eight months, study finds

A new study by researchers at Monash University, Australia, has revealed that people who have been infected with COVID-19 showed sustained protection against reinfection for at least eight months.

26 Nov 2020

Recurrent SARS-CoV-2 mutations do not significantly increase transmissibility, says study

A team of researchers at the Genetics Institute, University College London, tested whether any homoplasies observed in SARS-Cov-2 to date are significantly linked to increased viral transmission.

26 Nov 2020

Researchers discover blood gene signatures that can predict COVID-19 severity

A team of scientists from the University of Chicago, NCH Healthcare System and the University of South Florida has identified a specific set of genes associated with a poor prognosis of COVID-19.

26 Nov 2020

Researchers develop synthetic defective SARS-CoV-2 genome that inhibits viral replication

A shorter genome comprising only a part of the SARS-CoV-2's RNA genome competes with the normal virus for growth and can potentially prevent viral replication.

26 Nov 2020

Antihypertensive drugs may reduce COVID-19 mortality in at-risk patients

A new multicenter study that recently appeared on the medRxiv* preprint server in November 2020 has found a lower or equal risk of fatal COVID-19 in hypertensive patients, depending on the type of medication they are on.

26 Nov 2020

Phycobilins found to inhibit SARS-CoV-2 enzymes in vitro

Researchers have released an interesting new study that describes the broad-spectrum of antiviral activity that phycobilins can have. Phycobilins, which are bioactive plant compounds, were found to inhibit two coronavirus enzymes.

26 Nov 2020

Study shows lower light pollution during COVID-19 lockdown in Granada

A novel study reports a favorable change in light pollution during the lockdown in Granada, Spain, from March to May 2020, and has traced it back to several different causes related to COVID-19 lockdown measures.

26 Nov 2020

Early interferon therapy may mitigate COVID-19 severity

A recent review of COVID-19 therapies explores the utility of interferons in the battle against severe COVID-19, and concludes that they deserve further development.

26 Nov 2020

Early use of existing treatment helps save hospitalized COVID-19 patients

The lives of patients hospitalized with COVID-19 are being saved by doctors who are using an existing medical treatment at an earlier stage.

25 Nov 2020

Lungs of COVID-19 patients show good recovery in most cases

Lung tissue of patients who suffered severely from COVID-19 shows good recovery in most cases. This was revealed by a study carried out by the Radboud university medical center that has now been published in Clinical Infectious Diseases.

25 Nov 2020

Specific SARS-CoV-2 genomic variations are associated with higher COVID-19 deaths

A team of scientists from South Korea and the United States has conducted an interesting study to investigate whether mutations in the genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can affect the severity of coronavirus disease 2019 (COVID-19). The study findings reveal that mutations in the viral spike protein and RNA polymerase complex can increase the risk of COVID-19 mortality.

25 Nov 2020

COVID-19 vaccine candidate tested preclinically at UAB poised for Phase 1 clinical study

A COVID-19 vaccine candidate that underwent extensive preclinical testing at the University of Alabama at Birmingham this spring and summer is poised for clinical testing to begin in December.

25 Nov 2020

Half of the population is unaware of the relation between climate change and infectious diseases

Although it is a widely known scientific fact that infectious diseases emerge and re-emerge due to climate change, a study which included the involvement of the UAB published in PlosOne reveals that 48.9% of the population surveyed are not aware of this relation.

25 Nov 2020

Study sheds new light on genetic risk factors that make individuals susceptible to severe COVID-19

Even as tens of thousands of Americans test positive for COVID-19 each day, physicians still aren't sure why some people experience mild to no symptoms while others become critically ill.

25 Nov 2020

Inhibiting SARS-CoV-2 cell entry with monoclonal antibodies against staphylococcal enterotoxin B superantigen

In a recent cutting-edge study, US researchers unveiled an anti-staphylococcal enterotoxin B monoclonal antibody that can be repurposed to target the cleavage site of the SARS-CoV-2 spike glycoprotein and, in turn, inhibit viral infection. Their findings are currently available on bioRxiv preprint server.

25 Nov 2020

SARS-CoV-2 likely circulating in China as early as mid-October 2019

Researchers in the United States have conducted a modeling study suggesting that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – could have been circulating in the Chinese province of Hubei as early as mid-October 2019.

25 Nov 2020

Genomic analysis provides clues about SARS-CoV-2 ancestry and transmission

Researchers in the UK conducting a genomic analysis of severe acute respiratory virus syndrome coronavirus 2 (SARS-CoV-2) and SARS-like coronaviruses in the bat and pangolin have identified strong host-associated divergences that could provide clues about the ancestry and interspecies transmission of SARS-CoV-2.

25 Nov 2020

FDA issues guidance on use of dry heat to support reuse of certain respirators

Today, the U.S. Food and Drug Administration issued guidance on the use of dry heat to help support the single-user reuse of certain particulate filtering facepiece respirators (FFRs), such as N95 respirators, by health care personnel when there is a limited supply of respirators during the COVID-19 public health emergency.

25 Nov 2020

Disease/Infection News

Transgenic mouse model could recapitulate severe COVID-19 in humans

COVID-19 may trigger recurrent Guillain–Barré Syndrome episodes, a case study shows

SARS-CoV-2 immunity can sustain for at least eight months, study finds

Recurrent SARS-CoV-2 mutations do not significantly increase transmissibility, says study

Researchers discover blood gene signatures that can predict COVID-19 severity

Researchers develop synthetic defective SARS-CoV-2 genome that inhibits viral replication

Antihypertensive drugs may reduce COVID-19 mortality in at-risk patients

Phycobilins found to inhibit SARS-CoV-2 enzymes in vitro

Study shows lower light pollution during COVID-19 lockdown in Granada

Early interferon therapy may mitigate COVID-19 severity

Early use of existing treatment helps save hospitalized COVID-19 patients

Lungs of COVID-19 patients show good recovery in most cases

Specific SARS-CoV-2 genomic variations are associated with higher COVID-19 deaths

COVID-19 vaccine candidate tested preclinically at UAB poised for Phase 1 clinical study

Half of the population is unaware of the relation between climate change and infectious diseases

Study sheds new light on genetic risk factors that make individuals susceptible to severe COVID-19

Inhibiting SARS-CoV-2 cell entry with monoclonal antibodies against staphylococcal enterotoxin B superantigen

SARS-CoV-2 likely circulating in China as early as mid-October 2019

Genomic analysis provides clues about SARS-CoV-2 ancestry and transmission

FDA issues guidance on use of dry heat to support reuse of certain respirators

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

Latest News