Disease/Infection News

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Equine antibody preparation shows greater capacity to neutralize SARS-CoV-2 isolate than human convalescent plasma

A recent Brazilian study demonstrates that hyperimmune globulin formulations generated against the recombinant spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) provide significantly high antibody titer with highly neutralizing capacity. The study is currently available on the bioRxiv preprint server.

23 Aug 2020

No evidence pregnancy increases the risk of COVID-19 morbidity or severity

Albeit pregnancy is generally considered a significant risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and more severe coronavirus disease (COVID-19) outcomes, a recent study by a multinational team of researchers shows that symptoms are generally comparable between pregnant and non-pregnant cohorts of women – with the exception of gastrointestinal symptoms. This paper is currently available on the medRxiv* preprint server.

23 Aug 2020

Pfizer/BioNTech COVID-19 vaccine candidate BNT162b2 profiled for large scale clinical trials

Although two RNA-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidates elicited similar, dose-dependent neutralizing antibody titers in both younger and older adults, a recent study by researchers from the U.S. and Germany has shown that BNT162b2 is associated with less systemic reactogenicity in elderly individuals – supporting its selection for further phase 2/3 clinical trials. The study is currently available on medRxiv* preprint server.

23 Aug 2020

Scientific review on on link between air pollution and COVID-19

Researchers at Harvard T. H. Chan School of Public Health, Harvard University, and the Dana-Farber Cancer Institute have conducted a “state-of-the-science” review of the evidence available on potential associations between exposure to air pollution and health outcomes in coronavirus disease 2019 (COVID-19).

23 Aug 2020

Raccoon dogs potential intermediate host for SARS-CoV-2

Researchers at the Friedrich Loeffler Institute in Germany have conducted a study demonstrating that raccoon dogs were a potential intermediate host in the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

23 Aug 2020

Self-collected saliva and deep nasal swabs are equally effective for detecting SARS-CoV-2

Self-collected saliva and deep nasal swabs collected by healthcare providers are equally effective for detecting SARS-CoV-2, the virus that causes COVID-19, according to a new study conducted by ARUP Laboratories and University of Utah Health.

21 Aug 2020

New COVID-19 pooling test detects asymptomatic carriers

A new peer-reviewed study published in Science Advances confirms the success of a new COVID-19 pooling test that identifies all positive subjects, including asymptomatic carriers, in a single round of testing.

21 Aug 2020

Nasal vaccine effective in preventing COVID-19 infection in mice

Scientists at Washington University School of Medicine in St. Louis have developed a vaccine that targets the SARS-CoV-2 virus, can be given in one dose via the nose and is effective in preventing infection in mice susceptible to the novel coronavirus.

21 Aug 2020

Study offers insights into immune reactions in severe COVID-19

Researchers may have come one step closer toward understanding how the immune system contributes to severe COVID-19.

21 Aug 2020

New injectable drug could offer long-lasting protection from HIV with fewer side effects

Scientists have developed an injectable drug that blocks HIV from entering cells. They say the new drug potentially offers long-lasting protection from the infection with fewer side effects.

21 Aug 2020

COVID-19 patients most likely readmitted to hospital for respiratory distress, study finds

This study describes characteristics of patients with COVID-19 who returned to the ER or required readmission to the hospital within 14 days of being discharged. Understanding what conditions impact these patient outcomes can help improve care during the hospital stay and after discharge.

21 Aug 2020

VUMC receives $34 million grant for nationwide convalescent plasma study

Vanderbilt University Medical Center has been awarded a one-year, $34-million grant by the National Center for Advancing Translational Sciences, part of the National Institutes of Health, to conduct a nationwide study of "convalescent plasma" as a treatment for COVID-19.

21 Aug 2020

Strong feelings of germ aversion and pathogen disgust associated with preventative behavior

Creeped out by cooties? Grossed out by germs? Squeamish about sickness? If so, then you might also find yourself engaging in more preventative health behaviors, like frequent handwashing and disinfecting your living environment, during the ongoing coronavirus pandemic.

21 Aug 2020

Public confidence in the Swedish media is decreasing but has strengthened for government officials

Swedes perceive the tone of reporting on the coronavirus in the media as less hyped/alarmist than they did prior to the summer. Public confidence in the media is decreasing but has strengthened for government officials.

21 Aug 2020

Study: Many COVID-19 patients suffer cardiovascular damage even after recovery

One of the most harrowing effects of COVID-19 is severe damage to the lungs, which makes breathing hard or impossible for those who're severely affected.

21 Aug 2020

California’s data failures stymie efforts to curb the virus

The failure of California's infectious disease monitoring system for a stretch of at least 20 days in July and August triggered potentially deadly fallout that continues to reverberate across the state.

21 Aug 2020

Swab, spit, stay home? College coronavirus testing plans are all over the map

Yousuf El-Jayyousi, a junior engineering student at the University of Missouri, wanted guidance and reassurance that it would be safe to go back to school for the fall semester. He tuned into a pair of online town halls organized by the university hoping to find that.

21 Aug 2020

Deadly mix: How bars are fueling COVID-19 outbreaks

From the early days of the U.S. coronavirus outbreak, states have wrestled with the best course of action for bars and nightclubs, which largely have their economic prospects tied to social gatherings in tight quarters. As the virus has pinched the industry’s lifeblood, bar owners in a handful of states are fighting in court against government orders that they stay closed.

21 Aug 2020

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

A recent study by researchers at the Sanford Burnham Prebys Medical Discovery Institute and the University of California San Francisco and published on the preprint server bioRxiv in August 2020 shows that a protein encoded by the subgenomic sequence ORF9c of SARS-CoV-2 is responsible for the low antiviral response in infected humans, enabling the successful replication of the virus in the host.

21 Aug 2020

NPL scientists design a simple, low-cost ventilator

Scientists and engineers from the National Physical Laboratory have created a low cost and easy-to-manufacture ventilator design, in response to the need for affordable ventilator technologies in emerging markets.

21 Aug 2020