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Alzheimer's study shows tau protein changes according to dementia stage

Research into Alzheimer's disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients' brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain.

19 Nov 2020

UIC conducts three clinical trials to study blood clot prevention in COVID-19 patients

The University of Illinois Chicago will conduct three clinical trials for studying blood clot prevention in patients with COVID-19.

18 Nov 2020

COVID-19 during pregnancy can cause placental inflammation and impaired immunity

A new study conducted by a team of researchers at Johns Hopkins University, USA, has observed how pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) show stunted antiviral immune responses.

18 Nov 2020

Investigational drug helped improve heart health in patients with chronic conditions

The investigational medication finerenone reduced the risk of heart attack, stroke, heart failure and other negative cardiovascular events in patients with chronic kidney disease and Type 2 diabetes, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

17 Nov 2020

Combination of ticagrelor and aspirin reduces subsequent stroke risk in patients with heart plaque

Patients with plaque build-up in their arteries, who suffered a transient ischemic attack (TIA) or a minor ischemic stroke, also called a warning stroke, and were treated with the newer blood thinner ticagrelor plus aspirin were 27% less likely to have another stroke within 30 days, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

17 Nov 2020

Novel drug reduces the risk of cardiovascular events for patients with Type 2 diabetes, kidney disease

A novel diabetes medication significantly reduces the risk of hospitalization for heart failure, heart attack and stroke, in patients with Type 2 diabetes and chronic kidney disease, according to late breaking research presented today at the American Heart Association's Scientific Sessions 2020.

17 Nov 2020

Study shows favorable impact of medication on cardiac structure and function

For the first time, medication has impacted heart muscle thickness and function for patients with the most common inherited heart condition, rather than simply addressing their symptoms.

17 Nov 2020

Clinical trials show SGLT2 inhibitor may benefit patients with type 2 diabetes

Less than a decade ago, the Food and Drug Administration approved drugs for treating type 2 diabetes in an entirely new way.

16 Nov 2020

First-ever phase 3 advanced anal cancer trial opens for patient enrollment

The first randomized phase 3 clinical trial ever to be conducted in patients with advanced cancer of the anal canal is now open and enrolling patients.

16 Nov 2020

Antifungal agent Itraconazole inhibits SARS CoV-2 in vitro

Itraconazole is a broad-spectrum antifungal agent that has been shown to have some in vitro activity against SARS-CoV-2 by a team of Belgian and German researchers.

16 Nov 2020

Potent antiplatelet drug not superior to standard of care in reducing heart attack risk during angioplasty

The use of the more potent antiplatelet medication ticagrelor was not superior to clopidogrel in the reduction of the rate of heart attack or severe complications among people undergoing an elective procedure to open a blocked artery, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

16 Nov 2020

Moderna's COVID-19 vaccine nearly 95% effective

US company Moderna have just released their early phase 3 clinical trial results for their COVID-19 vaccine which is nearly 95% effective.

16 Nov 2020

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

A team of researchers from the Northern Arizona University evaluated a new PARP inhibitor, stenoparib, which has recently advanced to Stage II of clinical trials to treat ovarian cancer. Their study, an initial report on in vitro stenoparib activity against human coronaviruses such as SARS-CoV-2, has been published on the preprint server bioRxiv*.

15 Nov 2020

Diabetes drug can ameliorate lives of chronic heart failure patients

Empagliflozin, a recently developed diabetes drug, can effectively treat and reverse heart failure in both diabetic and non-diabetic patients, according to researchers at the Icahn School of Medicine at Mount Sinai.

15 Nov 2020

Immunotherapy combination shrinks rare angiosarcoma tumors in 25% of patients

Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute's Division of Cancer Diagnosis and Treatment, part of the National Institutes of Health, have shown that the immunotherapy combination of ipilimumab and nivolumab shrinks rare angiosarcoma tumors in 25 percent of all patients, with some having an even stronger response to the drug combination.

15 Nov 2020

Arthritis drug may improve COVID-19 survival among elderly patients

A type of arthritis drug may reduce the risk of dying for elderly patients with COVID-19.

15 Nov 2020

Polypill plus aspirin and polypill alone reduced cardiovascular disease risk

A single, daily pill combining blood pressure and cholesterol medications, along with the addition of a daily dose of aspirin, reduced cardiovascular disease events in people at risk for heart disease, according to late-breaking research presented today in a late-breaking clinical trial presentation at the American Heart Association's Scientific Sessions 2020.

15 Nov 2020

New medication may reduce risk for heart failure-related events in people with chronic heart failure

Omecamtiv mecarbil, a new, investigational heart medication, reduced the risk of heart failure-related events in patients with heart failure with reduced ejection fraction, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

15 Nov 2020

Antidepressant may prevent worsening of COVID-19 infection, study suggests

The antidepressant fluvoxamine appears to prevent COVID-19 infections from worsening and may help keep patients out of the hospital, a trial based on research from the University of Virginia School of Medicine suggests.

15 Nov 2020

Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

Now, a team of researchers at the Synairgen Research, Southampton General Hospital, Southampton, United Kingdom, has found that inhaled nebulized interferon beta-1a (SNG001), a drug used for multiple sclerosis, helped COVID-19 patients have greater odds of improvement and recovery from SARS-CoV-2 infection.

15 Nov 2020

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Drug Trial News

Alzheimer's study shows tau protein changes according to dementia stage

UIC conducts three clinical trials to study blood clot prevention in COVID-19 patients

COVID-19 during pregnancy can cause placental inflammation and impaired immunity

Investigational drug helped improve heart health in patients with chronic conditions

Combination of ticagrelor and aspirin reduces subsequent stroke risk in patients with heart plaque

Novel drug reduces the risk of cardiovascular events for patients with Type 2 diabetes, kidney disease

Study shows favorable impact of medication on cardiac structure and function

Clinical trials show SGLT2 inhibitor may benefit patients with type 2 diabetes

First-ever phase 3 advanced anal cancer trial opens for patient enrollment

Antifungal agent Itraconazole inhibits SARS CoV-2 in vitro

Potent antiplatelet drug not superior to standard of care in reducing heart attack risk during angioplasty

Moderna's COVID-19 vaccine nearly 95% effective

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

Diabetes drug can ameliorate lives of chronic heart failure patients

Immunotherapy combination shrinks rare angiosarcoma tumors in 25% of patients

Arthritis drug may improve COVID-19 survival among elderly patients

Polypill plus aspirin and polypill alone reduced cardiovascular disease risk

New medication may reduce risk for heart failure-related events in people with chronic heart failure

Antidepressant may prevent worsening of COVID-19 infection, study suggests

Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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