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Researchers receive $5.1 million to expand clinical trial of drug to prevent ARDS in COVID-19 patients

Researchers evaluating whether an investigational oral drug, vadadustat, can help prevent acute respiratory distress s to expand the Phase II clinical trial at The University of Texas Health Science Center at HoustonQ.

13 Jan 2021

Drug found to be safe and effective for treating patients with obesity and type 2 diabetes

A new study confirms that treatment with Bimagrumab, an antibody that blocks activin type II receptors and stimulates skeletal muscle growth, is safe and effective for treating excess adiposity and metabolic disturbances of adult patients with obesity and type 2 diabetes.

13 Jan 2021

Study shows how cardiosphere-derived cells replenish damaged tissues in dilated cardiomyopathy

Dilated cardiomyopathy (DCM) is a condition caused by the weakening of the heart muscle, affecting the ventricles (chambers in the heart that push blood around the body as it contracts).

13 Jan 2021

Lactating women should discuss risks and benefits of COVID-19 vaccination, says ABM

The Academy of Breastfeeding Medicine (ABM) does not recommend cessation of breastfeeding for individuals who are vaccinated against COVID-19.

13 Jan 2021

Study shows COVID-19 pneumonia is different from typical pneumonia

Bacteria or viruses like influenza that cause pneumonia can spread across large regions of the lung over the course of hours. In the modern intensive care unit, these bacteria or viruses are usually controlled either by antibiotics or by the body's immune system within the first few days of the illness.

12 Jan 2021

C-Path PRO Consortium measure now included in FDA-approved label claim

Critical Path Institute's (C-Path) Patient-Reported Outcome (PRO) Consortium announces that clinical study results using the Consortium's Diary for Irritable Bowel Syndrome Symptoms-Constipation (DIBSS-C) were recently included in the expanded label for the drug LINZESS® (linaclotide).

7 Jan 2021

Study: Antibiotics are not necessary after most endoscopic sinus surgeries

Antibiotics are not necessary for patients after most routine endoscopic sinus surgeries despite the common practice to prescribe them, according to a team led by researchers at Massachusetts Eye and Ear.

6 Jan 2021

UC-MSC infusions reduce risk of death, quicken recovery time in severe COVID-19 cases

Dr. Camilo Ricordi, director of the Diabetes Research Institute and Cell Transplant Center at the University of Miami Miller School of Medicine, and his team of international collaborators are reporting the results of a groundbreaking randomized controlled trial showing umbilical cord-derived mesenchymal stem cell (UC-MSC) infusions safely reduce risk of death and quicken time to recovery for the most severe COVID-19 patients.

5 Jan 2021

P2 COVID-19 study shows no material safety differences between opaganib and control arms

Preliminary data from the non-powered U.S. Phase 2 study of 40 hospitalized patients shows that orally-administered opaganib was safe, with no material safety differences between opaganib and control arms.

4 Jan 2021

Study shows mRNA-1273 vaccine can prevent symptomatic COVID-19 infection

A peer-reviewed paper published in The New England Journal of Medicine provides data from the much-anticipated COVE study, which evaluated mRNA-1273, a vaccine candidate against COVID-19 manufactured by Moderna, Inc.

3 Jan 2021

Phase 3 results show investigational vaccine is effective in preventing severe COVID-19

The investigational vaccine known as mRNA-1273 was 94.1% efficacious in preventing symptomatic coronavirus disease 2019 (COVID-19), according to preliminary results from a Phase 3 clinical trial reported in the New England Journal of Medicine.

3 Jan 2021

Phase 3 trial of Novavax COVID-19 vaccine candidate begins enrolling volunteers

The Phase 3 trial of another investigational coronavirus disease 2019 (COVID-19) vaccine has begun enrolling adult volunteers.

28 Dec 2020

Researchers test effects of full doses of anticoagulants in COVID-19 patients

Three clinical trial platforms working together to test the effects of full doses of anticoagulants (blood thinners) in COVID-19 patients have paused enrollment for one group of patients.

23 Dec 2020

Phase 2/3 COVID-19 study evaluates safety, potential identification of preliminary efficacy signals

Top-line data from the 270-patient global Phase 2/3 COVID-19 study expected Q1/2021. Top-line data from the 40-patient U.S. Phase 2 study of opaganib in severe COVID-19 expected in the coming days; this non-powered study was designed to evaluate safety and potential identification of preliminary efficacy signals in support of the global Phase 2/3 study of opaganib.

23 Dec 2020

Early clinical data demonstrates the efficacy of existing drug in treating COVID-19

In what has the potential to significantly change how Corona patients are being treated and the severity of the disease, research spearheaded at Jerusalem's Hebrew University gathered early clinical evidence demonstrating the efficacy of an existing drug in treating COVID-19.

22 Dec 2020

First patient enrolled in Phase II clinical trial of stem cell therapy for traumatic injuries

The first patient has enrolled in a Phase II clinical trial evaluating a stem cell therapy for the potential early treatment of traumatic injuries and their subsequent complications at The University of Texas Health Science Center at Houston.

21 Dec 2020

Novel SARS-CoV-2 neutralizing antibody enters Phase 1/2a clinical study

Cologne University Hospital (UKK), University of Marburg (UMR), the German Center for Infection Research (DZIF) and Boehringer Ingelheim today announced the initiation of Phase 1/2a clinical investigation of BI 767551, a new SARS-CoV-2 neutralizing antibody.

18 Dec 2020

Study recommends blinded crossover and continued follow-ups to evaluate SARS-CoV-2 vaccine durability

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Drug Trial News

Researchers receive $5.1 million to expand clinical trial of drug to prevent ARDS in COVID-19 patients

Drug found to be safe and effective for treating patients with obesity and type 2 diabetes

Study shows how cardiosphere-derived cells replenish damaged tissues in dilated cardiomyopathy

Lactating women should discuss risks and benefits of COVID-19 vaccination, says ABM

Study shows COVID-19 pneumonia is different from typical pneumonia

C-Path PRO Consortium measure now included in FDA-approved label claim

Study: Antibiotics are not necessary after most endoscopic sinus surgeries

UC-MSC infusions reduce risk of death, quicken recovery time in severe COVID-19 cases

P2 COVID-19 study shows no material safety differences between opaganib and control arms

Study shows mRNA-1273 vaccine can prevent symptomatic COVID-19 infection

Phase 3 results show investigational vaccine is effective in preventing severe COVID-19

Phase 3 trial of Novavax COVID-19 vaccine candidate begins enrolling volunteers

Researchers test effects of full doses of anticoagulants in COVID-19 patients

Phase 2/3 COVID-19 study evaluates safety, potential identification of preliminary efficacy signals

Early clinical data demonstrates the efficacy of existing drug in treating COVID-19

First patient enrolled in Phase II clinical trial of stem cell therapy for traumatic injuries

Novel SARS-CoV-2 neutralizing antibody enters Phase 1/2a clinical study

Study recommends blinded crossover and continued follow-ups to evaluate SARS-CoV-2 vaccine durability

FDA approves pembrolizumab as first-line treatment for colorectal cancer

Vi-DT typhoid conjugate vaccine met primary endpoints in phase III study

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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