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Antenatal steroids improve preterm newborn survival in low-resource settings, finds study

The results of a new clinical trial, published today in the New England Journal of Medicine, show that dexamethasone- a glucocorticoid used to treat many conditions, including rheumatic problems and severe COVID-19- can boost survival of premature babies when given to pregnant women at risk of preterm birth in low-resource settings.

23 Oct 2020

Clinical trial launched to test existing drugs for treatment of a rare blood cancer

A clinical trial designed to test existing drugs in the treatment of a rare blood cancer has been launched at the Universities of Birmingham and Warwick.

23 Oct 2020

Age can affect response to adjuvant treatment among patients with resected melanoma

Younger patients with resected melanoma had some benefit from adjuvant treatment with the anti-VEGF therapeutic bevacizumab (Avastin) while older patients with resected melanoma did not

23 Oct 2020

High-impact clinical trial results could improve kidney-related medical care

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25.

23 Oct 2020

Investigational drug offers benefits for patients with chronic kidney disease and type 2 diabetes

The findings, simultaneously published in the New England Journal of Medicine and presented at the American Society of Nephrology's Kidney Week 2020 conference, show the investigational drug finerenone had tangible renal and cardiovascular benefits for patients with chronic kidney disease and type 2 diabetes.

23 Oct 2020

Bedfont virtually opens first overseas office in Austria

On 3rd September, Bedfont hosted a virtual launch party to open their first overseas office, Bedfont GmbH, based in Salzburg, Austria. Earlier this year Bedfont announced the acquisition of its former distributor, Dr Lahner Medizintechnik, which now serves as the new GmbH headquarters.

From Bedfont® Scientific Ltd 23 Oct 2020

DNA vaccine-induced antibodies neutralize SARS-CoV-2

The coronavirus disease (COVID-19) is far from over as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to ravage across the globe. With the vast spread of the virus, many countries who reported flattening the curve over the past months have reported clusters of new cases and second waves of the outbreak.

22 Oct 2020

Hydroxychloroquine does not prevent COVID-19 in health care workers, trial shows

University of Minnesota Medical School physician researchers studied hydroxychloroquine as a treatment to prevent COVID-19 for those with high-risk for exposure to the virus - health care workers.

21 Oct 2020

First COPD patient treated with RejuvenAir System in a multicenter clinical trial

Temple University Hospital has treated the first patient in a multicenter international clinical trial utilizing the RejuvenAir System for the treatment of patients suffering from moderate to severe chronic obstructive pulmonary disease with chronic bronchitis.

21 Oct 2020

Promising interim results for Sinopharm's inactivated whole-virion SARS-CoV-2 vaccine

The COVID-19 pandemic has led to intensive scientific efforts to bring about an effective vaccine for global distribution. Many different vaccine design approaches are underway. A recent study published in the journal The Lancet Infectious Diseases in October 2020 reports a potentially successful inactivated virus vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

19 Oct 2020

Sinopharm's candidate SARS-CoV-2 vaccine BBIBP-CorV shows promise in clinical trials

Researchers in China have conducted a phase 1/2 trial demonstrating the safety, tolerability, and immunogenicity of a candidate vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

18 Oct 2020

WHO study finds Remdesivir and other repurposed drugs ineffective in COVID-19

A large-scale randomized trial has recently been conducted by the World Health Organization (WHO) to evaluate the efficacy of four repurposed antiviral medicines, including Remdesivir, Hydroxychloroquine, Lopinavir, and Interferon, currently used to treat hospitalized coronavirus disease 2019 (COVID-19) patients.

18 Oct 2020

Experimental ALS drug shows potential to prolong patient survival

An experimental medication that was recently shown to slow the progression of the neurodegenerative disease amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, has now demonstrated the potential to also prolong patient survival.

16 Oct 2020

NIH launches adaptive Phase 3 clinical trial to test immune modulator drugs in COVID-19 patients

The National Institutes of Health has launched an adaptive Phase 3 clinical trial to evaluate the safety and efficacy of three immune modulator drugs in hospitalized adults with COVID-19.

16 Oct 2020

Control trial proves effectiveness of repurposed drugs for COVID-19 treatment

In just six months, the world's largest randomized control trial on COVID-19 therapeutics has generated conclusive evidence on the effectiveness of repurposed drugs for the treatment of COVID-19.

16 Oct 2020

MITHRAS trial investigates superiority of TMVR-induced iASD over medical therapy

The MITHRAS randomized clinical trial found that interventional closure of an iatrogenic atrial septal defect (iASD) driven by transcatheter mitral valve repair (TMVR) was not superior to conservative medical treatment with regard to the primary endpoint of change in six-minute walking distance.

16 Oct 2020

Sanofi Translate Bio MRT5500 COVID-19 vaccine shows promise in preclinical trials

The COVID-19 pandemic is threatening to come back in greater intensity during the winter and fall. Faced with this threat, vaccine development efforts are entering a phase of renewed focus, attempting to identify antigens capable of eliciting protective levels of neutralizing antibodies. A new study published on the preprint server bioRxiv* in October 2020 reports on a novel mRNA vaccine candidate's performance in two animal models.

16 Oct 2020

The COVID-19 vaccine pipeline

Researchers from Mayo Clinic, United States of America, have reviewed the immunity developed against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19 disease.

14 Oct 2020

New clinical trial to test safety and efficacy of antibody cocktail against COVID-19

In a new clinical trial, UC Davis Health will test the effectiveness and safety of REGN-COV2, the monoclonal antibody cocktail, in preventing COVID-19 in adults living with infected patients.

14 Oct 2020

Genoscience Pharma's GNS561 shows potential against SARS-CoV-2 in vitro

A new study published on the preprint server bioRxiv in October 2020 shows that a combination of a new compound GNS561 and remdesivir act synergistically against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This suggests that autophagy inhibitors could be an alternative strategy for SARS-CoV-2 infection.

12 Oct 2020

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Drug Trial News

Antenatal steroids improve preterm newborn survival in low-resource settings, finds study

Clinical trial launched to test existing drugs for treatment of a rare blood cancer

Age can affect response to adjuvant treatment among patients with resected melanoma

High-impact clinical trial results could improve kidney-related medical care

Investigational drug offers benefits for patients with chronic kidney disease and type 2 diabetes

Bedfont virtually opens first overseas office in Austria

DNA vaccine-induced antibodies neutralize SARS-CoV-2

Hydroxychloroquine does not prevent COVID-19 in health care workers, trial shows

First COPD patient treated with RejuvenAir System in a multicenter clinical trial

Promising interim results for Sinopharm's inactivated whole-virion SARS-CoV-2 vaccine

Sinopharm's candidate SARS-CoV-2 vaccine BBIBP-CorV shows promise in clinical trials

WHO study finds Remdesivir and other repurposed drugs ineffective in COVID-19

Experimental ALS drug shows potential to prolong patient survival

NIH launches adaptive Phase 3 clinical trial to test immune modulator drugs in COVID-19 patients

Control trial proves effectiveness of repurposed drugs for COVID-19 treatment

MITHRAS trial investigates superiority of TMVR-induced iASD over medical therapy

Sanofi Translate Bio MRT5500 COVID-19 vaccine shows promise in preclinical trials

The COVID-19 vaccine pipeline

New clinical trial to test safety and efficacy of antibody cocktail against COVID-19

Genoscience Pharma's GNS561 shows potential against SARS-CoV-2 in vitro

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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